公开(公告)号：US08485025B2

公开(公告)日：2013-07-16

申请号：US12851220

申请日：2010-08-05

申请人： Shane Woody ,  Jennifer Weller

发明人： Shane Woody ,  Jennifer Weller

IPC分类号： G01B5/28 ,  G01N29/02

CPC分类号： G01N29/022 ,  G01N29/036 ,  G01N2291/02466 ,  G01N2291/0427

摘要： The present invention provides a standing wave fiber assembly for the collection and detection of a biological target in a complex biological fluid, including: an oscillator; and an elongated fiber coupled to the oscillator, wherein the elongated fiber is selectively exposed to a fluid potentially containing the biological target, and wherein the resonated elongated fiber attracts the biological target, and wherein a change in a response of the resonated elongated fiber indicates the presence of the biological target. The assembly also includes a top cover plate including one or more electrical connections and a port through which the fluid is introduced. The assembly further includes a bottom cover plate including a well in which the fluid is contained. Optionally, the elongated fiber includes one or more probes homogenously functionalized along its length that bind targeted biological materials.

摘要翻译： 本发明提供了一种用于收集和检测复杂生物流体中的生物靶的驻波纤维组件，包括：振荡器; 以及耦合到所述振荡器的细长纤维，其中所述细长纤维选择性地暴露于潜在地包含所述生物靶的流体，并且其中所述共振细长纤维吸引所述生物靶，并且其中所述共振细长纤维的响应变化指示 存在生物目标。 组件还包括顶盖板，其包括一个或多个电连接件和流体被引入的端口。 组件还包括底盖板，其包括容纳流体的井。 任选地，细长纤维包括沿其长度均匀地官能化结合目标生物材料的一个或多个探针。

公开(公告)号：US20100297746A1

公开(公告)日：2010-11-25

申请号：US12851220

申请日：2010-08-05

申请人： Shane WOODY ,  Jennifer Weller

发明人： Shane WOODY ,  Jennifer Weller

IPC分类号： C12M1/34

CPC分类号： G01N29/022 ,  G01N29/036 ,  G01N2291/02466 ,  G01N2291/0427

摘要： The present invention provides a standing wave fiber assembly for the collection and detection of a biological target in a complex biological fluid, including: an oscillator; and an elongated fiber coupled to the oscillator, wherein the elongated fiber is selectively exposed to a fluid potentially containing the biological target, and wherein the resonated elongated fiber attracts the biological target, and wherein a change in a response of the resonated elongated fiber indicates the presence of the biological target. The assembly also includes a top cover plate including one or more electrical connections and a port through which the fluid is introduced. The assembly further includes a bottom cover plate including a well in which the fluid is contained. Optionally, the elongated fiber includes one or more probes homogenously functionalized along its length that bind targeted biological materials.

摘要翻译： 本发明提供了一种用于收集和检测复杂生物流体中的生物靶的驻波纤维组件，包括：振荡器; 以及耦合到所述振荡器的细长纤维，其中所述细长纤维选择性地暴露于潜在地包含所述生物靶的流体，并且其中所述共振细长纤维吸引所述生物靶，并且其中所述共振细长纤维的响应变化指示 存在生物目标。 组件还包括顶盖板，其包括一个或多个电连接件和流体被引入的端口。 组件还包括底盖板，其包括容纳流体的井。 任选地，细长纤维包括沿其长度均匀地官能化结合目标生物材料的一个或多个探针。

公开(公告)号：US20070240516A1

公开(公告)日：2007-10-18

申请号：US11818669

申请日：2007-06-15

申请人： Marcin Bauza ,  Shane Woody ,  Stuart Smith

发明人： Marcin Bauza ,  Shane Woody ,  Stuart Smith

IPC分类号： G12B21/20

CPC分类号： B25J7/00 ,  B25J15/022 ,  B25J15/10 ,  G01Q80/00 ,  Y10S977/849 ,  Y10S977/85 ,  Y10S977/851 ,  Y10S977/86 ,  Y10S977/863 ,  Y10S977/872 ,  Y10S977/873 ,  Y10S977/876 ,  Y10S977/88

摘要： The present invention provides a self-sensing tweezer device for micro and nano-scale manipulation, assembly, and surface modification, including: one or more elongated beams disposed in a first configuration; one or more oscillators coupled to the one or more elongated beams, wherein the one or more oscillators are operable for selectively oscillating the one or more elongated beams to form one or more “virtual” probe tips; and an actuator coupled to the one or more elongated beams, wherein the actuator is operable for selectively actuating the one or more elongated beams from the first configuration to a second configuration.

摘要翻译： 本发明提供一种用于微尺度和纳米尺度操纵，组装和表面改性的自感镊子装置，包括：一个或多个沿第一构型设置的细长梁; 耦合到所述一个或多个细长波束的一个或多个振荡器，其中所述一个或多个振荡器可操作用于选择性地振荡所述一个或多个细长波束以形成一个或多个“虚拟”探针尖端; 以及联接到所述一个或多个细长梁的致动器，其中所述致动器可操作以选择性地将所述一个或多个细长梁从所述第一构型激活到第二构型。

公开(公告)号：US20050242258A1

公开(公告)日：2005-11-03

申请号：US11106400

申请日：2005-04-14

申请人： Marcin Bauza ,  Stuart Smith ,  Shane Woody

发明人： Marcin Bauza ,  Stuart Smith ,  Shane Woody

IPC分类号： F16C17/10 ,  F16C25/02 ,  G11B5/54

CPC分类号： F16C17/10 ,  F16C23/043 ,  F16C25/02

摘要： A symmetric ultra-precision spindle design in which all forces of constraint are, within the tolerances of manufacturing and assembly processes, symmetrically arranged about its axis. Additionally this design may require little or no external power other than the forces to rotate the spindle.

摘要翻译： 对称的超精密主轴设计，其中所有约束力都在制造和组装过程的公差内，围绕其轴线对称排列。 另外，除了旋转主轴的力之外，该设计可能需要很少的或没有外部的力量。