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1.发明申请MONOCLONAL AND OLIGOCLONAL ANTI-EGFR ANTIBODIES FOR USE IN THE TREATMENT OF TUMORS EXPRESSING PREDOMINANTLY HIGH AFFINITY EGFR LIGANDS OR TUMORS EXPRESSING PREDOMINANTLY LOW AFFINITY EGFR LIGANDS 有权用于治疗肿瘤的单克隆抗体和寡核苷酸抗EGFR抗体，其表达预期的高亲和力EGFR配体或肿瘤，表达预期的低亲和力EGFR配体公开(公告)号：US20120308576A1
公开(公告)日：2012-12-06
申请号：US13488270
申请日：2012-06-04
IPC分类号： C07K16/28 , A61P35/00 , A61K39/395 , C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , A61K9/0019 , A61K39/3955 , A61K39/39558 , A61K2039/505 , A61K2039/507 , C07K14/71 , C07K16/2863 , C07K16/30 , C07K16/32 , C07K2317/21 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12Q1/686 , C12Q2600/106 , G01N33/57484 , G01N33/57496 , G01N33/74 , G01N2333/485 , G01N2333/495 , G01N2800/52
摘要： Disclosed are pharmaceutical preparations for, and methods for determining, appropriate and effective treatment with therapeutic agents comprising a single species of anti-EGFR monoclonal antibody or therapeutic agents comprising a plurality of species of such antibodies, as well as kits useful for making such determinations.
摘要翻译： 公开了用于治疗药物的药物制剂和用于确定适当和有效治疗的药物制剂，所述治疗药物包含单种抗EGFR单克隆抗体或包含多种此类抗体的治疗剂，以及用于进行此类测定的试剂盒。
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2.发明授权Methods of treatment of tumors expressing predominantly high affinity EGFR ligands or tumors expressing predominantly low affinity EGFR ligands with monoclonal and oligoclonal anti-EGFR antibodies 有权主要表达高亲和力EGFR配体或主要表达低亲和力EGFR配体的肿瘤的单克隆抗体和寡克隆抗EGFR抗体的治疗方法公开(公告)号：US08691231B2
公开(公告)日：2014-04-08
申请号：US13488270
申请日：2012-06-04
IPC分类号： A61K39/395 , G01N33/567 , A61K38/18 , A61P35/00
CPC分类号： C12Q1/6886 , A61K9/0019 , A61K39/3955 , A61K39/39558 , A61K2039/505 , A61K2039/507 , C07K14/71 , C07K16/2863 , C07K16/30 , C07K16/32 , C07K2317/21 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12Q1/686 , C12Q2600/106 , G01N33/57484 , G01N33/57496 , G01N33/74 , G01N2333/485 , G01N2333/495 , G01N2800/52
摘要： Disclosed are pharmaceutical preparations for, and methods for determining, appropriate and effective treatment with therapeutic agents comprising a single species of anti-EGFR monoclonal antibody or therapeutic agents comprising a plurality of species of such antibodies, as well as kits useful for making such determinations.
摘要翻译： 公开了用于治疗药物的药物制剂和用于确定适当和有效治疗的药物制剂，所述治疗药物包含单种抗EGFR单克隆抗体或包含多种此类抗体的治疗剂，以及用于进行此类测定的试剂盒。
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