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    DIAGNOSING AND PROTECTING HORSES AGAINST PAPILLOMAVIRUS
    2.
    发明申请
    DIAGNOSING AND PROTECTING HORSES AGAINST PAPILLOMAVIRUS 审中-公开
    诊断和保护马尾TING虫

    公开(公告)号：US20100317567A1

    公开(公告)日：2010-12-16

    申请号：US12861409

    申请日：2010-08-23

    Applicant: A. Bennett Jenson ,  Shin-je Ghim ,  Victoria B. Kyle ,  Joongho Joh

    Inventor： A. Bennett Jenson ,  Shin-je Ghim ,  Victoria B. Kyle ,  Joongho Joh

    IPC: A61K38/02 ,  C12Q1/70 ,  A61P31/20

    CPC classification number: C12Q1/708 ,  A61K38/162 ,  A61K39/12 ,  A61K2039/5258 ,  A61K2039/552 ,  C07K14/005 ,  C12N7/00 ,  C12N2710/20022 ,  C12N2710/20023 ,  C12N2710/20034 ,  G01N33/6854 ,  G01N2333/025

    Abstract: Compositions for conferring protection against Equus caballus papillomavirus (EcPV) and Bovine papillomavirus (BPV) infection in a subject are provided and include a virus-like particle assembled from an EcPV L1 protein and virus like particle assembled from a BPV L1 protein. Methods for protecting a subject against EcPV and BPV infection are further provided and include administering to the subject a composition comprised of a virus-like particle assembled from an EcPV L1 protein and virus like particle assembled from a BPV L1 protein. Methods of diagnosing EcPV and/or BPV infection in a subject are also provided and include providing a virus-like particle assembled from a papillomavirus L1 protein selected from an EcPV L1 protein and a BPV L1 protein; contacting the virus-like particle with serum from the subject; and identifying the subject as having an infection if an antibody capable of binding the virus-like particle is detected in the serum.

    Abstract translation: 提供了在受试者中赋予对马尾猴乳头瘤病毒（EcPV）和牛乳头瘤病毒（BPV）感染的保护作用的组合物，包括由EcPV L1蛋白组装的病毒样颗粒和由BPV L1蛋白组装的病毒样颗粒。 还提供了保护受试者免受EcPV和BPV感染的方法，包括向受试者施用由EcPV L1蛋白组装的病毒样颗粒和由BPV L1蛋白组装的病毒样颗粒组成的组合物。 还提供了诊断受试者中EcPV和/或BPV感染的方法，包括提供从选自EcPV L1蛋白和BPV L1蛋白的乳头瘤病毒L1蛋白组装的病毒样颗粒; 使病毒样颗粒与受试者的血清接触; 并且如果在血清中检测到能够结合病毒样颗粒的抗体，则将受试者识别为感染。

    DIAGNOSING AND PROTECTING HORSES AGAINST PAPILLOMAVIRUS
    7.
    发明申请
    DIAGNOSING AND PROTECTING HORSES AGAINST PAPILLOMAVIRUS 审中-公开
    诊断和保护马尾TING虫

    公开(公告)号：US20090011996A1

    公开(公告)日：2009-01-08

    申请号：US12167581

    申请日：2008-07-03

    Applicant: A. Bennett Jenson ,  Shin-je Ghim ,  Victoria B. Kyle ,  Joongho Joh

    Inventor： A. Bennett Jenson ,  Shin-je Ghim ,  Victoria B. Kyle ,  Joongho Joh

    IPC: A61K38/16 ,  C12Q1/70 ,  A61P31/12

    CPC classification number: C12Q1/708 ,  A61K38/162 ,  A61K39/12 ,  A61K2039/5258 ,  A61K2039/552 ,  C07K14/005 ,  C12N7/00 ,  C12N2710/20022 ,  C12N2710/20023 ,  C12N2710/20034 ,  G01N33/6854 ,  G01N2333/025

    Abstract: Compositions for conferring protection against Equus caballus papillomavirus (EcPV) and Bovine papillomavirus (BPV) infection in a subject are provided and include a virus-like particle assembled from an EcPV L1 protein and virus like particle assembled from a BPV L1 protein. Methods for protecting a subject against EcPV and BPV infection are further provided and include administering to the subject a composition comprised of a virus-like particle assembled from an EcPV L1 protein and virus like particle assembled from a BPV L1 protein. Methods of diagnosing EcPV and/or BPV infection in a subject are also provided and include providing a virus-like particle assembled from a papillomavirus L1 protein selected from an EcPV L1 protein and a BPV L1 protein; contacting the virus-like particle with serum from the subject; and identifying the subject as having an infection if an antibody capable of binding the virus-like particle is detected in the serum.

    Abstract translation: 提供了在受试者中赋予对马尾猴乳头瘤病毒（EcPV）和牛乳头瘤病毒（BPV）感染的保护作用的组合物，包括由EcPV L1蛋白组装的病毒样颗粒和由BPV L1蛋白组装的病毒样颗粒。 还提供了保护受试者免受EcPV和BPV感染的方法，包括向受试者施用由EcPV L1蛋白组装的病毒样颗粒和由BPV L1蛋白组装的病毒样颗粒组成的组合物。 还提供了诊断受试者中EcPV和/或BPV感染的方法，包括提供从选自EcPV L1蛋白和BPV L1蛋白的乳头瘤病毒L1蛋白组装的病毒样颗粒; 使病毒样颗粒与受试者的血清接触; 并且如果在血清中检测到能够结合病毒样颗粒的抗体，则将受试者识别为感染。

    Diagnosing and protecting against tursiops truncatus papillomavirus
    8.
    发明授权
    Diagnosing and protecting against tursiops truncatus papillomavirus 失效
    诊断和防止蠕形切除乳头瘤病毒

    公开(公告)号：US07445786B1

    公开(公告)日：2008-11-04

    申请号：US11733557

    申请日：2007-04-10

    Applicant: Manuela Rehtanz ,  A. Bennett Jenson ,  Shin-je Ghim ,  Gregory D. Bossart

    Inventor： Manuela Rehtanz ,  A. Bennett Jenson ,  Shin-je Ghim ,  Gregory D. Bossart

    IPC: A61K39/12

    CPC classification number: C12N7/00 ,  A61K39/12 ,  A61K2039/5258 ,  C12N2710/20023 ,  C12N2710/20034

    Abstract: Composition for conferring protection against Tursiops truncatus papillomavirus (TtPV) infection in a subject includes a virus-like particle assembled from at least one type of TtPV L1 protein. Methods for protecting a subject against TtPV infection include administering to the subject an immunogenic composition including a virus-like particle assembled from at least one type of TtPV L1 protein. Methods for diagnosing TtPV infection in a subject include providing a virus-like particle assembled from at least one TtPV L1 protein; contacting the virus-like particle with serum obtained from the subject; and identifying the subject as having TtPV infection if a TtPV antibody capable of binding the virus-like particle is detected in the serum.

    Abstract translation: 用于赋予受试者针对Tursiops truncatus papillomavirus（TtPV）感染的组合物包括由至少一种类型的TtPV L1蛋白组装的病毒样颗粒。 用于保护受试者免受TtPV感染的方法包括向受试者施用包含由至少一种类型的TtPV L1蛋白组装的病毒样颗粒的免疫原性组合物。 在受试者中诊断TtPV感染的方法包括提供由至少一种TtPV L1蛋白组装的病毒样颗粒; 使病毒样颗粒与从受试者获得的血清接触; 并且如果在血清中检测到能够结合病毒样颗粒的TtPV抗体，则鉴定受试者具有TtPV感染。

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