摘要:
Methods for enhancing the suppressive function of myeloid derived suppressor cells (MDSCs) for the treatment of autoimmune diseases using small compounds are disclosed. In certain aspects, the small compounds are glatiramer acetate and mitogen activated protein (MAP) kinase inhibitors. In other aspects, these methods include the administration of exogenous MDSCs or the use of endogenous MDSCs mobilized using stem cell mobilizers. In yet other aspects, compositions containing MDSCs and small compounds of the invention are provided.
摘要:
This invention discloses an optical system design, which is used in a liquid crystal display apparatus. The optical system design at least comprises a light generation module, a circular polarization module and a liquid crystal light valve, wherein the light generation module is used to generate a light, the circular polarization module is used to modulate the polarization state of the light to a circular polarization state, and the liquid crystal light valve is used to modulate the polarization state of the light, so as to modulate the intensity of the light to show the image. The optical system design is able to solve the problem of fringing-field effects.
摘要:
A device for enhancing the linear polarization intensity of light which passes through a polarizer is provided, which comprises: a prepolarizer receiving incident natural light and splitting the natural light into a plurality of polarized light beams with different polarization directions, changing the polarization direction of the light beams, thereby enhancing the light intensity of a particular polarization direction; and a polarizer having polarization direction the same as that of the prepolarizer, receiving the light emitted from the prepolarizer, and then converting the light into a linearly polarized light.
摘要:
An apparatus for selecting waveguide modes in optical fibers is disclosed, which comprises an optical fiber having of a core and a cladding sheathing the core. The optical fiber has a selected portion of the cladding removed and forms a recessed space in the cladding while preserving a predetermined thickness of the cladding remaining covering the core. The optical fiber is selected for allowing the transmission of light having multiple waveguide modes with radial and azimuthal electric field components. The apparatus further comprises a birefringent material filled in the recessed space. The birefringent material has the first and second refractive indices and the first refractive index is larger than the core index of the optical fiber, while the second refractive index is smaller than the cladding index of the optical fiber. The first and second refractive indices of the birefringent material are arranged in the radial and azimuthal directions of the optical fiber respectively, so that the transmitted light of the waveguide mode with the radial electric field component is coupled out from the core of the optical fiber to the selective portion of the cladding, and the transmitted light of the waveguide mode with only the azimuthal electric field component remains transmitted through the optical fiber.
摘要:
A bistable chiral tilted-homeotropic nematic liquid crystal (BCTHN) display can be switched between the tilted-homeotropic state (TH state) and the twisted state (T state) by using dual frequency liquid crystal material. These two states can be maintained without the application of any electric field. The bistable liquid crystal display does not need high voltage to induce the flow of liquid crystal or break the anchoring energy.
摘要:
The present invention relates to novel myeloid suppressor cells (MSCs) and to methods of isolating these MSCs are also included. The MSCs of the present invention can be used to treat or prevent autoimmune diseases or alloimmune responses. The MSCs of the present invention may also be used to reduce a T cell response, induce T regulatory cells, and produce T cell tolerance.
摘要:
Compositions and methods for diagnosing and treating tumors using myeloid derived suppressor cells (MDSCs) are provided. More particularly, the compositions contain labeled MDSCs or MDSCs in combination with oncolytic viruses, nano-particles or other anti-tumor agents.
摘要:
Methods for enhancing the suppressive function of myeloid derived suppressor cells (MDSCs) for the treatment of autoimmune diseases using small compounds are disclosed. In certain aspects, the small compounds are glatiramer acetate and mitogen activated protein (MAP) kinase inhibitors. In other aspects, these methods include the administration of exogenous MD-SCs or the use of endogenous MDSCs mobilized using stem cell mobilizers. In yet other aspects, compositions containing MDSCs and small compounds of the invention are provided.
摘要:
The invention relates to methods of isolating, culturing, and differentiating myeloid derived suppressor cells (MD-SCs) from embryonic stem (ES) cells and hematopoietic stem cells (HSCs). In certain embodiments, the invention relates to methods and compositions for producing MDSCs from ES cells and HSCs using a combination of factors including macrophage colony-stimulating factor (M-CSF).
摘要:
A fiber-optic interferometer is provided. The interferometer includes a first dual-mode optical fiber for receiving a light input and exciting a first and a second spatial, modes, a first modal processor connected to the first dual-mode optical fiber for selecting the first and the second spatial modes, a second dual-mode optical fiber connected to the first modal processor for propagating the first and the second spatial modes and producing a phase shift (Δφ) between the first and the second spatial modes in response to an external perturbation effect, a second modal processor connected to the second dual-mode optical fiber for re-selecting the first and the second spatial modes and producing a first light output interference pattern, and an analyzer connected to the second modal filter for adjusting the first light output interference pattern to produce a second light output interference pattern.