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    Apparatus and methods for analysis and sorting of particles such as polymer beads
    1.
    发明申请
    Apparatus and methods for analysis and sorting of particles such as polymer beads 有权
    用于分析和分选诸如聚合物珠粒子的装置和方法

    公开(公告)号：US20090025489A1

    公开(公告)日：2009-01-29

    申请号：US10583997

    申请日：2004-12-22

    申请人： Soeren Flygenring Christensen ,  Ib Johannsen

    发明人： Soeren Flygenring Christensen ,  Ib Johannsen

    IPC分类号： G01N1/00

    CPC分类号： G01N21/645 ,  B01J2219/00468 ,  B01J2219/005 ,  B01J2219/00551 ,  C40B70/00 ,  G01N2015/149 ,  G01N2021/6417 ,  G01N2035/00574

    摘要： The present invention relates to an apparatus for analysing beads and particles, such as polymer beads used e.g. for solid phase synthesis. The apparatus in one embodiment comprises a rotatable, circular disc comprising a plurality of through-going inlets, wherein an individual bead from a composition comprising different beads can be fixed to the disc at the end-position of a through-going inlet by applying a pressure drop over said disc comprising said through-going inlets. The pressure drop results in beads being sucked (i.e. detachably fixed) onto the disc on top of the through-going inlets. When the disc is rotated the beads are transferred from the position where they initially became attached to the disc to fixed positions wherein suitable devices for measuring and/or analysing and/or sorting the beads can be operated in order to e.g. measure and/or analyse and/or sort at least one bead of a plurality of beads. More specifically, the invention relates to an apparatus for measuring a plurality of optically detectable beads, such as polymer beads, said apparatus comprising a) a vacuum container comprising at least one planar capture body capable of rotating around a central axis, wherein said capture body comprises a plurality of through-going inlets, and wherein the diameter of each inlet is smaller than the average diameter of the beads to be measured and/or analysed and/or sorted, b) a pressure controlling device capable of controlling the pressure in the vacuum container, c) a device for rotating the vacuum container around the axis of the capture disc, and d) a device for measuring at least one property of at least one bead.

    摘要翻译： 本发明涉及一种用于分析珠粒和颗粒的装置，例如聚合物珠，例如聚合物珠。 用于固相合成。 在一个实施例中的装置包括可旋转的圆盘，其包括多个贯穿入口，其中来自包含不同珠粒的组合物的单个珠粒可以在通入入口的终端位置处固定到盘上， 所述盘上的压降包括所述贯穿入口。 压力下降导致珠被吸入（即可拆卸地固定）到贯穿入口的顶部上的盘上。 当盘旋转时，珠粒从它们最初附着到盘的位置转移到固定位置，其中用于测量和/或分析和/或分选珠粒的合适的装置可以操作以便例如 测量和/或分析和/或排列多个珠粒的至少一个珠粒。 更具体地，本发明涉及一种用于测量多个可光学检测的珠粒（例如聚合物珠粒）的装置，所述装置包括：a）真空容器，其包括能够围绕中心轴线旋转的至少一个平面捕获体，其中所述捕获体 包括多个贯通入口，并且其中每个入口的直径小于待测量和/或分析和/或分选的珠粒的平均直径; b）压力控制装置，其能够控制在 真空容器，c）用于围绕捕获盘的轴线旋转真空容器的装置，以及d）用于测量至少一个珠粒的至少一个性质的装置。

    Apparatus and methods for analysis and sorting of particles such as polymer beads
    2.
    发明授权
    Apparatus and methods for analysis and sorting of particles such as polymer beads 有权
    用于分析和分选诸如聚合物珠粒子的装置和方法

    公开(公告)号：US07869011B2

    公开(公告)日：2011-01-11

    申请号：US10583997

    申请日：2004-12-22

    申请人： Soeren Flygenring Christensen ,  Ib Johannsen

    发明人： Soeren Flygenring Christensen ,  Ib Johannsen

    IPC分类号： G01J3/44

    CPC分类号： G01N21/645 ,  B01J2219/00468 ,  B01J2219/005 ,  B01J2219/00551 ,  C40B70/00 ,  G01N2015/149 ,  G01N2021/6417 ,  G01N2035/00574

    摘要： The present invention relates to an apparatus for analysing beads and particles, such as polymer beads used e.g. for solid phase synthesis. The apparatus comprises a) a vacuum container comprising at least one planar capture body capable of rotating around a central axis, wherein said capture body comprises a plurality of through-going inlets, and wherein the diameter of each inlet is smaller than the average diameter of the beads to be measured and/or analysed and/or sorted, b) a pressure controlling device capable of controlling the pressure in the vacuum container, c) a device for rotating the vacuum container around the axis of the capture body, and d) a device for measuring at least one property of at least one bead, the apparatus further comprising a capture body support, supporting the capture body, and a vacuum container housing.

    摘要翻译： 本发明涉及一种用于分析珠粒和颗粒的装置，例如聚合物珠，例如聚合物珠。 用于固相合成。 该设备包括：a）真空容器，其包括能够围绕中心轴线旋转的至少一个平面捕获体，其中所述捕获体包括多个通入入口，并且其中每个入口的直径小于 要测量和/或分析和/或分类的珠粒，b）能够控制真空容器中的压力的​​压力控制装置，c）围绕捕获体的轴线旋转真空容器的装置，以及d） 用于测量至少一个珠粒的至少一个性质的装置，所述装置还包括捕获体支撑件，支撑捕获体和真空容器壳体。