公开(公告)号：US20170296673A1

公开(公告)日：2017-10-19

申请号：US15516687

申请日：2015-10-06

申请人： Andreas VOIGT ,  Sonja LEHMANN ,  Anja VOIGT ,  Therakine BioDelivery GmbH

发明人： Andreas VOIGT ,  Sonja LEHMANN ,  Anja VOIGT

IPC分类号： A61K47/44 ,  A61K47/22 ,  A61K47/12 ,  A61K47/42 ,  A61K36/064

CPC分类号： A61K47/44 ,  A61K36/064 ,  A61K47/12 ,  A61K47/22 ,  A61K47/42

摘要： The present invention discloses a drug delivery system comprising at least one hydrophobic matrix and at least one pharmaceutically active compound. The hydrophobic matrix comprises at least one hydrophobic solid component and at least one hydrophobic liquid component. The pharmaceutically active compound may comprise a biological cell or a biopolymer. The hydrophobic matrix conserves the activity of and protects the functionality of the biological cell or biopolymer in hostile environment, at elevated temperature, cold temperatures or a combination thereof. The present invention also discloses the use of the drug delivery system in a kit for diagnostic or analytical purposes. Additionally, the present invention discloses the use of the drug delivery system to deliver the pharmaceutically active compound to a subject who has or is suspected of having a pathophysiological condition.

公开(公告)号：US20160250146A1

公开(公告)日：2016-09-01

申请号：US15083879

申请日：2016-03-29

申请人： Andreas Voigt ,  Scott Hampton ,  Andreas Reiff ,  Sonja Lehmann ,  Joerg Kriwanek

发明人： Andreas Voigt ,  Scott Hampton ,  Andreas Reiff ,  Sonja Lehmann ,  Joerg Kriwanek

IPC分类号： A61K9/06 ,  A61K47/10 ,  C07K16/00 ,  A61K47/12 ,  A61K47/14 ,  A61K39/395 ,  A61K47/44

CPC分类号： A61K9/06 ,  A61K9/14 ,  A61K39/00 ,  A61K39/395 ,  A61K47/02 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/22 ,  A61K47/44 ,  A61K47/46 ,  A61K2039/505 ,  C07K16/00

摘要： A method for manufacturing a drug-delivery composition includes providing at least a pharmaceutically active composition, providing a hydrophobic matrix; and mixing the hydrophobic matrix and the pharmaceutically active composition to form a paste-like or semi-solid drug-delivery composition.

摘要翻译： 制备药物递送组合物的方法包括提供至少一种药物活性组合物，提供疏水基质; 并混合疏水基质和药物活性组合物以形成糊状或半固体药物递送组合物。

公开(公告)号：US20170252301A1

公开(公告)日：2017-09-07

申请号：US15517973

申请日：2015-10-08

申请人： Andreas VOIGT ,  Sonja LEHMANN ,  Annette BA-ZANDT ,  Therakine BioDelivery GmbH

发明人： Andreas Voigt ,  Sonja Lehmann ,  Annette Assogba-Zandt

IPC分类号： A61K9/14 ,  C07K16/00

CPC分类号： A61K9/145 ,  A61K9/1682 ,  A61K9/5094 ,  A61K9/5123 ,  A61K9/5192 ,  A61K39/39591 ,  C07K16/00 ,  C07K2317/94

摘要： Disclosed are biocompatible composite nanoparticles and methods of preparing biocompatible composite nanoparticles. Also disclosed ate composite nanoparticles which are biocompatible, biodegradable and have numerous other advantages, and also examples of preparation of the nanoparticles and applications for intracellular delivery.