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公开(公告)号：US20170296673A1
公开(公告)日：2017-10-19
申请号：US15516687
申请日：2015-10-06
发明人： Andreas VOIGT , Sonja LEHMANN , Anja VOIGT
IPC分类号： A61K47/44 , A61K47/22 , A61K47/12 , A61K47/42 , A61K36/064
CPC分类号： A61K47/44 , A61K36/064 , A61K47/12 , A61K47/22 , A61K47/42
摘要： The present invention discloses a drug delivery system comprising at least one hydrophobic matrix and at least one pharmaceutically active compound. The hydrophobic matrix comprises at least one hydrophobic solid component and at least one hydrophobic liquid component. The pharmaceutically active compound may comprise a biological cell or a biopolymer. The hydrophobic matrix conserves the activity of and protects the functionality of the biological cell or biopolymer in hostile environment, at elevated temperature, cold temperatures or a combination thereof. The present invention also discloses the use of the drug delivery system in a kit for diagnostic or analytical purposes. Additionally, the present invention discloses the use of the drug delivery system to deliver the pharmaceutically active compound to a subject who has or is suspected of having a pathophysiological condition.
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公开(公告)号：US20180265652A1
公开(公告)日：2018-09-20
申请号：US15517974
申请日：2015-10-07
发明人： Andreas VOIGT , Sonja LEHMANN , Mariana DOBRANIS
CPC分类号： C08J3/24 , A61K8/65 , A61K8/735 , A61K2800/91 , A61L27/20 , A61L27/52 , A61L2400/06 , A61L2430/34 , A61Q19/08 , C08J2305/08
摘要： Disclosed are macroscopic systems of highly concentrated, cross-linked biopolymers. The macroscopic system is created by combining a biopolymer with a cross-linking agent, submerging the resulting product in an aqueous solution which contains additional cross-linking agents, to allow the biopolymer to undergo a second cross-linking process. The resulting macroscopic biopolymer has an increased biopolymer concentration and increased longevity within the body.
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