公开(公告)号：US09808585B2

公开(公告)日：2017-11-07

申请号：US14002177

申请日：2012-03-15

申请人： Stefan Wendland ,  Steffen Raab ,  Peggy Rabe

发明人： Stefan Wendland ,  Steffen Raab ,  Peggy Rabe

IPC分类号： A61M5/50 ,  A61M5/24

CPC分类号： A61M5/5086 ,  A61M5/24 ,  A61M5/50

摘要： A drug delivery device for administering a dose of a medicament by way of injection is disclosed, the device including a housing to receive a cartridge at least partially filled with a medicament and being sealed with a piston slidably disposed therein, a drive mechanism having a piston rod to be displaced in a distal direction to operably engage with the piston of the cartridge, a dose button operably engaged with the drive mechanism for at least one of preparing or initiating a dose dispensing action of the drive mechanism, and a protective member adapted to impede actuation of the dose button, wherein the protective member is releasably connected to the housing via a breakable seal.

公开(公告)号：US09802004B2

公开(公告)日：2017-10-31

申请号：US13393331

申请日：2010-09-03

申请人： Steffen Raab ,  Sandra Arnhold

发明人： Steffen Raab ,  Sandra Arnhold

IPC分类号： A61M5/315 ,  A61M5/24

CPC分类号： A61M5/31593 ,  A61M5/24 ,  A61M5/31551 ,  A61M5/31583 ,  A61M5/31585

摘要： A piston rod is arranged in a body and provided with a helical element and an axial element. A guide element, which is arranged in the body and fixed relatively to the body, is coupled to the helical element to guide a helical movement of the piston rod and coupled to the axial element to guide an axial movement of the piston rod. The axial movement allows a priming of the device preceding the helical movement of the piston rod.

公开(公告)号：US09737666B2

公开(公告)日：2017-08-22

申请号：US13504296

申请日：2010-11-01

申请人： Philippe Nzike ,  Steffen Raab ,  Uwe Dasbach ,  Uwe Boeser ,  Ulrich Bruggemann ,  Brice Ulrich Tchouadje ,  Kevin Igor Youmbi Ngatchou

发明人： Philippe Nzike ,  Steffen Raab ,  Uwe Dasbach ,  Uwe Boeser ,  Ulrich Bruggemann

IPC分类号： A61M5/315 ,  A61M5/24

CPC分类号： A61M5/31535 ,  A61M5/24 ,  A61M5/31555 ,  A61M5/31556 ,  A61M5/31585 ,  A61M2005/2407 ,  A61M2205/581 ,  A61M2205/582

摘要： An assembly for a drug delivery device is disclosed. An example assembly includes a housing, a rotation member, a drive member, and at least one correction member. The rotation member is adapted to be rotated with respect to the housing in a first rotational direction for delivering a dose of a drug. The drive member is coupleable to the rotation member for delivering the dose. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in the first rotational direction due to mechanical interaction of the rotation member and the drive member. In a correction mode, the rotation member and the drive member are decoupled such that the rotation member is rotatable in the first rotational direction with respect to the drive member.

公开(公告)号：US09623185B2

公开(公告)日：2017-04-18

申请号：US13701969

申请日：2011-06-09

申请人： Steffen Raab ,  Mark Philip Horlock ,  Stephen David Butler

发明人： Steffen Raab ,  Mark Philip Horlock ,  Stephen David Butler

IPC分类号： A61M5/315 ,  A61M5/24

CPC分类号： A61M5/31511 ,  A61M5/24 ,  A61M5/31543 ,  A61M5/3155 ,  A61M5/31551 ,  A61M5/31553 ,  A61M5/31555 ,  A61M5/3158 ,  A61M5/31583 ,  A61M5/31585

摘要： An assembly for a drug delivery device is provided, comprising a housing, a rotation member adapted and arranged to be rotated in a first and in a second rotational direction with respect to the housing in an operational mode of the assembly, a drive member which is configured to mechanically cooperate with the rotation member such that the drive member follows rotation of the rotation member when the rotation member is rotated in the second rotational direction and such that the rotation member rotates with respect to the drive member when the rotation member is rotated in the first rotational direction, and a piston rod. The assembly further comprises at least one biasing member which is adapted and arranged to provide a force tending to bring the rotation member and the drive member out of mechanical cooperation in the operational mode. The assembly is switchable from the operational mode into a reset mode. For switching from the operational mode into the reset mode, the biasing member is configured to drive a relative axial movement between the drive member and the rotation member such that the rotation member and the drive member are brought out of mechanical cooperation. Furthermore, a drug delivery device is provided.

公开(公告)号：US09381305B2

公开(公告)日：2016-07-05

申请号：US13258162

申请日：2010-03-31

申请人： Michael Harms ,  Steffen Raab ,  Udo Stauder

发明人： Michael Harms ,  Steffen Raab ,  Udo Stauder

IPC分类号： A61M5/315 ,  A61M5/31

CPC分类号： A61M5/31525 ,  A61M5/315 ,  A61M5/31543 ,  A61M2005/3115

摘要： The medical device comprises a wave spring or wave washer in a mechanism to engage or disengage a first element and a second element. The invention also discloses the use of a multiple wave spring or wave washer comprising at least two waved spring layers in a medical device.

摘要翻译： 该医疗装置包括波形弹簧或波形垫圈，其在与第一元件和第二元件接合或分离的机构中。 本发明还公开了在医疗装置中使用包括至少两个波形弹簧层的多波形弹簧或波形垫圈。

公开(公告)号：US09078973B2

公开(公告)日：2015-07-14

申请号：US13258151

申请日：2010-03-31

申请人： Michael Harms ,  Steffen Raab ,  Uwe Dasbach ,  Udo Stauder

发明人： Michael Harms ,  Steffen Raab ,  Uwe Dasbach ,  Udo Stauder

IPC分类号： A61M5/31 ,  A61M5/32

CPC分类号： A61M5/3129 ,  A61M5/3135 ,  A61M5/321 ,  A61M2005/3139

摘要： A drug delivery device comprises an outer housing rollable around a rotation axis and at least one stop member. The stop member protrudes radially from the outer housing of the drug delivery device and is configured to prevent rolling movement of the drug delivery device along a predetermined surface. The outer housing comprises a main housing and a dose member. The dose member is movable with respect to the main housing when setting and/or delivering a dose of a drug. The stop member comprises a first part and a second part, wherein the first part is arranged on the main housing and the second part is arranged on the dose member.

摘要翻译： 药物输送装置包括围绕旋转轴线可滚动的外壳体和至少一个止动件。 止动构件从药物输送装置的外壳径向地突出并且构造成防止药物输送装置沿着预定表面的滚动运动。 外壳包括主壳体和剂量构件。 当设置和/或递送药物的剂量时，剂量构件可相对于主壳体移动。 止挡构件包括第一部分和第二部分，其中第一部分布置在主壳体上，并且第二部分布置在剂量构件上。

公开(公告)号：US09022992B2

公开(公告)日：2015-05-05

申请号：US13512180

申请日：2010-12-02

申请人： Michael Helmer ,  Steffen Raab

发明人： Michael Helmer ,  Steffen Raab

IPC分类号： A61M5/00 ,  A61M5/315 ,  A61M5/31 ,  A61M5/24

CPC分类号： A61M5/31555 ,  A61M5/24 ,  A61M5/3146 ,  A61M5/3156 ,  A61M5/3158 ,  A61M5/31593 ,  A61M2005/31506

摘要： A drug delivery device comprises a housing and a piston rod arranged in the housing. The piston rod is adapted to be moved along an axial direction to dispense a fluid. A drive member arranged in the housing is operatively coupled to the piston rod and adapted to set up a dose of fluid for dispense in response to a first movement. The drive member is also adapted to move the piston rod to dispense the dose in response to a second movement. The drug delivery device also comprises a pre-dispensing drive member operatively coupled to the drive member and the housing and adapted to move at least the drive member by a pre-dispensing distance between its first and second movement.

摘要翻译： 药物输送装置包括设置在壳体中的壳体和活塞杆。 活塞杆适于沿轴向移动以分配流体。 布置在壳体中的驱动构件可操作地联接到活塞杆并且适于设置响应于第一运动而分配的剂量的流体。 驱动构件还适于移动活塞杆以响应于第二运动而分配剂量。 药物递送装置还包括预分配驱动构件，其可操作地联接到驱动构件和壳体并且适于在其第一和第二运动之间通过预分配距离至少移动驱动构件。

公开(公告)号：US20130338600A1

公开(公告)日：2013-12-19

申请号：US14002179

申请日：2012-03-16

申请人： Michael Helmer ,  Claudia Matthias ,  Lutz Mueller ,  Steffen Raab ,  Peter Nober ,  Reza Shahbazfar ,  Benjamin Schäfer ,  Leo Zeimetz

发明人： Michael Helmer ,  Claudia Matthias ,  Lutz Mueller ,  Steffen Raab ,  Peter Nober ,  Reza Shahbazfar ,  Benjamin Schäfer ,  Leo Zeimetz

IPC分类号： A61M5/31

CPC分类号： A61M5/31 ,  A61M5/24 ,  Y10T29/49826

摘要： A drug delivery device for dispensing of a dose of a medicinal product is presented comprising a first housing component having a receptacle being oval- or elliptically shaped in radial cross section and being adapted to at least partially receive an insert portion of a second housing component being at least partially insertable into said first housing component along an axial direction, wherein the insert portion is oval- or elliptically shaped in radial cross section. The outside dimension or an at least one outside diameter of the insert portion is at least in sections larger than a corresponding inner dimension or an at least one inner diameter of the receptacle and wherein the insert portion and the receptacle are adapted to generate a radially acting mutual clamping of first and second housing components in a pre-fixing assembly configuration.

摘要翻译： 提供了一种用于分配药物产品剂量的药物递送装置，其包括第一壳体部件，所述第一壳体部件具有椭圆形或椭圆形的径向横截面并且适于至少部分地容纳第二壳体部件的插入部分， 至少部分地沿着轴向方向插入所述第一壳体部件中，其中所述插入部分在径向横截面上呈椭圆形或椭圆形。 插入部分的外部尺寸或至少一个外径至少部分地大于插座的对应内部尺寸或至少一个内径，并且其中插入部分和插座适于产生径向作用 将第一和第二壳体部件相互夹紧在预定义组件构造中。

公开(公告)号：US20130110054A1

公开(公告)日：2013-05-02

申请号：US13509601

申请日：2010-12-06

申请人： Steffen Raab ,  Uwe Dasbach

发明人： Steffen Raab ,  Uwe Dasbach

IPC分类号： A61M5/315

CPC分类号： A61M5/31586 ,  A61M5/3146 ,  A61M5/31501 ,  A61M5/31541 ,  A61M5/31555 ,  A61M5/31556 ,  A61M5/3156 ,  A61M5/31573 ,  A61M5/31575 ,  A61M5/31585 ,  A61M5/31593

摘要： A drive assembly for a drug delivery device, comprising a housing with a proximal end and a distal end, and a longitudinal axis (A) extending between the proximal end and the distal end, a rotation sleeve being rotatable relative to the housing, and a piston rod being axially moveable relative to the housing. The piston rod is in mechanical cooperation with the rotation sleeve to be rotatable and moveable in the distal direction relative to the housing when the rotation sleeve rotates in a first direction (D1) and to be stationary in axial direction relative to the housing when the rotation sleeve rotates in a second direction (D2) opposite to the first direction (D1).

摘要翻译： 一种用于药物输送装置的驱动组件，包括具有近端和远端的壳体，以及在近端和远端之间延伸的纵向轴线（A），旋转套筒可相对于壳体旋转，并且 活塞杆相对于壳体可轴向移动。 当旋转套筒沿第一方向（D1）旋转时，活塞杆与旋转套筒机械协作以相对于壳体在远端方向上可旋转并且可移动，并且当旋转轴线相对于壳体在轴向方向上静止时 套筒沿与第一方向（D1）相反的第二方向（D2）旋转。

公开(公告)号：US08366680B2

公开(公告)日：2013-02-05

申请号：US12333462

申请日：2008-12-12

申请人： Steffen Raab

发明人： Steffen Raab

IPC分类号： A61M5/00

CPC分类号： A61M5/31501 ,  A61M5/24 ,  A61M5/3148 ,  A61M5/31511 ,  A61M5/31515 ,  A61M5/31535 ,  A61M5/31536 ,  A61M5/31541 ,  A61M5/31543 ,  A61M5/31551 ,  A61M5/31555 ,  A61M5/31556 ,  A61M5/31558 ,  A61M5/3156 ,  A61M5/31561 ,  A61M5/3157 ,  A61M5/31575 ,  A61M5/3158 ,  A61M5/31581 ,  A61M5/31585 ,  A61M5/31593 ,  A61M2005/2407 ,  A61M2005/3125 ,  A61M2005/3126 ,  A61M2005/3152 ,  A61M2205/581 ,  A61M2205/582 ,  F16H25/12 ,  Y10T74/18568 ,  Y10T74/18696

摘要： A resettable drive mechanism comprising a housing, a drive member rotatable in a second direction for delivering a dose of a medication, a piston rod driven by the drive member when it rotates in the second direction. A stop member prevents rotation of the drive member in a first direction opposite to the second direction, when the stop member engages the drive member. A clutch member is movable between a delivery position and a reset position. When the clutch member is in the delivery position, the stop member and the drive member are engaged and the drive member is prevented from rotating in the first direction, and when the clutch member is in the reset position, the drive member and the stop member are disengaged, the drive member is rotatable in the first direction and the piston rod is movable in the proximal direction.

摘要翻译： 一种可复位的驱动机构，包括壳体，可沿第二方向转动的用于输送剂量的药物的驱动构件;当驱动构件在第二方向旋转时由该驱动构件驱动的活塞杆。 当止动构件接合驱动构件时，止动构件防止驱动构件沿与第二方向相反的第一方向旋转。 离合器构件可在输送位置和复位位置之间移动。 当离合器构件处于输送位置时，停止构件和驱动构件接合，并且防止驱动构件沿第一方向旋转，并且当离合器构件处于复位位置时，驱动构件和止动构件 所述驱动构件能够沿着所述第一方向旋转，并且所述活塞杆能够在近端方向上移动。