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12 条记录 (耗时 0.038 秒)

    Lighting and/or indicating device equipped with a device for regulating the luminous flux for a halogen bulb
    1.
    发明授权
    Lighting and/or indicating device equipped with a device for regulating the luminous flux for a halogen bulb 失效
    配备有用于调节卤素灯泡的光通量的装置的照明和/或指示装置

    公开(公告)号：US08760070B2

    公开(公告)日：2014-06-24

    申请号：US11048537

    申请日：2005-02-01

    申请人： Loic Flandre ,  Stephane Richard

    发明人： Loic Flandre ,  Stephane Richard

    IPC分类号： H05B41/16

    CPC分类号： H05B39/047 ,  B60Q1/0094 ,  B60Q1/143 ,  F21S41/17 ,  Y02B20/144

    摘要： The present invention relates to a lighting and/or indicating device, such as a vehicle headlamp, equipped with at least one halogen bulb, wherein it comprises a switch-mode power supply device for supplying power to the halogen bulb, said switch-mode power supply device comprising means for regulating the luminous flux provided by the halogen bulb and being installed close to the halogen bulb so as to minimize electromagnetic interference and dispersion of the supply voltage at the terminals of the halogen bulb.

    摘要翻译： 本发明涉及一种配备有至少一个卤素灯泡的照明和/或指示装置，例如车辆前照灯，其中包括用于向卤素灯泡供电的开关模式电源装置，所述开关模式电源 供给装置包括用于调节由卤素灯泡提供的光通量并且安装在卤素灯泡附近的装置，以便使卤素灯泡的端子处的电磁干扰和电源电压的分散最小化。

    Lighting and/or indicating device equipped with a device for regulating the luminous flux for a halogen bulb
    2.
    发明申请
    Lighting and/or indicating device equipped with a device for regulating the luminous flux for a halogen bulb 失效
    配备有用于调节卤素灯泡的光通量的装置的照明和/或指示装置

    公开(公告)号：US20050169005A1

    公开(公告)日：2005-08-04

    申请号：US11048537

    申请日：2005-02-01

    申请人： Loic Flandre ,  Stephane Richard

    发明人： Loic Flandre ,  Stephane Richard

    IPC分类号： H05B39/04 ,  F21V7/00 ,  F21V7/04

    CPC分类号： H05B39/047 ,  B60Q1/0094 ,  B60Q1/143 ,  F21S41/17 ,  Y02B20/144

    摘要： The present invention relates to a lighting and/or indicating device, such as a vehicle headlamp, equipped with at least one halogen bulb, wherein it comprises a switch-mode power supply device for supplying power to the halogen bulb, said switch-mode power supply device comprising means for regulating the luminous flux provided by the halogen bulb and being installed close to the halogen bulb so as to minimize electromagnetic interference and dispersion of the supply voltage at the terminals of the halogen bulb.

    摘要翻译： 本发明涉及一种配备有至少一个卤素灯泡的照明和/或指示装置，例如车辆前照灯，其中包括用于向卤素灯泡供电的开关模式电源装置，所述开关模式电源 供给装置包括用于调节由卤素灯泡提供的光通量并且安装在卤素灯泡附近的装置，以便使卤素灯泡的端子处的电磁干扰和电源电压的分散最小化。

    LED control device for a vehicle light
    3.
    发明授权
    LED control device for a vehicle light 失效
    车载灯用LED控制装置

    公开(公告)号：US08419243B2

    公开(公告)日：2013-04-16

    申请号：US13007427

    申请日：2011-01-14

    申请人： Loic Flandre ,  Stephane Richard ,  Benjamin Touzet

    发明人： Loic Flandre ,  Stephane Richard ,  Benjamin Touzet

    IPC分类号： B60Q1/00

    CPC分类号： H05B33/0848

    摘要： The invention relates to a device for controlling diode lamps comprising a lighting module having at least one diode lamp, the diode lamp pertaining to a predefined range, at least one device for transmitting a unique signature representing the range, and an associated control module comprising reception means (for receiving a unique signature transmitted by the lighting module, and current adjustment means for adjusting and supplying, as a function of the transmitted signature, a current to said lighting module to cause the diode lamp to operate.

    摘要翻译： 本发明涉及一种用于控制二极管灯的装置，其包括具有至少一个二极管灯的照明模块，属于预定范围的二极管灯，用于发送表示该范围的唯一签名的至少一个装置，以及包括接收的相关控制模块 用于接收由照明模块发送的唯一签名的装置，以及用于根据发送的签名调整和供应到所述照明模块以使二极管灯工作的电流的电流调节装置。

    Illumination device for vanity mirrors of motor vehicles sun visors
    6.
    发明申请
    Illumination device for vanity mirrors of motor vehicles sun visors 有权
    汽车遮阳板的化妆镜的照明装置

    公开(公告)号：US20070258256A1

    公开(公告)日：2007-11-08

    申请号：US11353333

    申请日：2006-02-14

    申请人： Stephane Richard ,  Vincent Bernard

    发明人： Stephane Richard ,  Vincent Bernard

    IPC分类号： B60Q1/00

    CPC分类号： B60J3/0282

    摘要： The present invention relates to an illumination device for vanity mirrors of motor vehicle sun visors. The illumination device does not use cables as conducting elements nor external mechanical elements such as switches, simplifying the assembly operations. A conducting laminar element performs all of these functions: in addition to being the conducting means it acts as a switch for the device. This device is actuated by a cover that covers the mirror and is operated at the user's will. The device is characterised in that it is only illuminated in one position, in which the cover is not covering the mirror and the visor is in a shading position.

    摘要翻译： 本发明涉及一种汽车遮阳板的梳妆镜的照明装置。 照明装置不使用电缆作为导电元件，也不使用诸如开关的外部机械元件，从而简化组装操作。 导电层状元件执行所有这些功能：除了作为导电装置之外，它还用作器件的开关。 该装置由覆盖镜子的盖子驱动，并以用户的意愿操作。 该装置的特征在于它仅在一个位置被照亮，其中盖不覆盖反射镜并且遮阳板处于遮蔽位置。

    Method of screening inhibitors of mevalonate-independent isoprenoid biosynthetic pathway
    9.
    发明授权
    Method of screening inhibitors of mevalonate-independent isoprenoid biosynthetic pathway 有权
    筛选甲羟戊酸依赖型异戊二烯生物合成途径抑制剂的方法

    公开(公告)号：US07286973B1

    公开(公告)日：2007-10-23

    申请号：US10240636

    申请日：2001-05-03

    申请人： Joseph P. Noel ,  Marianne E. Bowman ,  Stephane Richard

    发明人： Joseph P. Noel ,  Marianne E. Bowman ,  Stephane Richard

    IPC分类号： G06G7/58 ,  C12N9/00

    CPC分类号： C12N9/1205 ,  C40B30/02 ,  G06F19/16 ,  G06F19/706 ,  Y02A90/26

    摘要： The present invention provides the structure of the enzyme 4-diphosphocytidyl-2-C-methylerythritol (CDP-ME) synthase, a member of the cytidyltransferase family of enzymes from Escherichia coli. CDP-ME is a critical intermediate in the mevalonate-independent pathway for isoprenoid biosynthesis in a number of prokaryotic organisms, in algae, in the plastids of plants, and in the malaria parasite. Since vertebrates synthesize isoprenoid precursors using a mevalonate pathway, CDP-ME synthase and other enzymes of the mevalonate-independent pathway for isoprenoid production represent attractive targets for the structure-based design of selective antibacterial, herbicidal, and antimalarial drugs. Accordingly, the present invention provides methods for screening for compounds that inhibit enzymes of the mevalonate-independent pathway and pharmaceutical compositions and antibacterial formulations thereof. Further provided are methods of inhibiting the enzymes of the pathway and bacterial terpenoid synthesis and methods for treating a subject suffering from a bacterial infection.

    摘要翻译： 本发明提供了来自大肠杆菌的酶的β-二磷酸胞苷基-2-C-甲基赤藓糖醇（CDP-ME）合酶的细胞质转移酶家族的成员的结构。 CDP-ME是许多原核生物，藻类，植物质体和疟疾寄生虫中异戊二烯生物合成中甲羟甲酸非依赖途径的关键中间体。 由于脊椎动物使用甲羟戊酸途径合成类异戊二烯前体，所以CDP-ME合酶和甲醛酸非依赖性途径用于类异戊二烯生产的其它酶代表了选择性抗菌，除草和抗疟药物基于结构的设计的有吸引力的目标。 因此，本发明提供了筛选抑制甲羟戊酸依赖性途径的酶的化合物的方法及其药物组合物及其抗菌制剂。 还提供了抑制途径的酶和细菌萜类化合物合成的方法以及治疗患有细菌感染的受试者的方法。

    Novel aromatic prenyltransferases, nucleic acids encoding same and uses therefor
    10.
    发明申请
    Novel aromatic prenyltransferases, nucleic acids encoding same and uses therefor 有权
    新型芳香族异戊烯基转移酶，编码相同的核酸，用于此

    公开(公告)号：US20060183211A1

    公开(公告)日：2006-08-17

    申请号：US11342328

    申请日：2006-01-27

    申请人： Tomohisa Kuzuyama ,  Joseph Noel ,  Stephane Richard

    发明人： Tomohisa Kuzuyama ,  Joseph Noel ,  Stephane Richard

    IPC分类号： C07H21/04

    CPC分类号： C12N9/1085

    摘要： In accordance with the present invention, a novel aromatic prenyltransferase, Orf2 from Streptomyces sp. strain CL190, involved in naphterpin biosynthesis has been identified and the structure thereof elucidated. This prenyltransferase catalyzes the formation of a C—C bond between a prenyl group and a compound containing an aromatic nucleus, and also displays C—O bond formation activity. Numerous crystallographic structures of the prenyltransferase have been solved and refined, e.g., (1) prenyltransferase complexed with a buffer molecule (TAPS), (2) prenyltransferase as a binary complex with geranyl diphosphate (GPP) and Mg2+, and prenyltransferase as ternary complexes with a non-hydrolyzable substrate analogue, geranyl S-thiolodiphosphate (GSPP) and either (3) 1,6-dihydroxynaphthalene (1,6-DHN), or (4) flaviolin (i.e., 2,5,7-trihydroxy-1,4-naphthoquinone, which is the oxidized product of 1,3,6,8-tetrahydroxynaphthalene (THN)). These structures have been solved and refined to 1.5 Å, 2.25 Å, 1.95 Å and 2.02 Å, respectively. This first structure of an aromatic prenyltransferase displays an unexpected and non-canonical (β/α)-barrel architecture. The complexes with both aromatic substrates and prenyl containing substrates and analogs delineate the active site and are consistent with a proposed electrophilic mechanism of prenyl group transfer. These structures also provide a mechanistic basis for understanding prenyl chain length determination and aromatic co-substrate recognition in this structurally unique family of aromatic prenyltransferases. This structural information is useful for predicting the aromatic prenyltransferase activity of proteins.

    摘要翻译： 根据本发明，一种新型芳族异戊烯基转移酶，来自链霉菌属的Orf2。 已经鉴定了参与萘普生生物合成的菌株CL190，其结构被阐明。 该异戊烯基转移酶催化异戊烯基和含有芳香核的化合物之间的C-C键的形成，并且还显示C-O键的形成活性。 已经解决和改进了异戊烯基转移酶的许多晶体结构，例如（1）与缓冲分子（TAPS）复合的异戊烯基转移酶，（2）作为二进位配合物的异戊烯基转移酶与香叶基二磷酸酯（GPP）和Mg 2+ （3）1,6-二羟基萘（1,6-DHN）或（4）黄堇素（即2号）的三钠配合物， ，5,7-三羟基-1,4-萘醌，其为1,3,6,8-四羟基萘（THN）的氧化产物）。 这些结构分别被解析和精炼成1.5A，2.25，1.95和2.02。 芳族异戊烯基转移酶的这种第一结构显示出意想不到的和非规范（β/α） - 杆状结构。 具有芳香底物和含异戊烯基的底物和类似物的络合物描绘了活性位点，并与提出的异戊烯基转移的亲电子机制一致。 这些结构还提供了在这个结构独特的芳族异戊烯基转移酶家族中了解异戊烯基链长度测定和芳香族共底物识别的机理基础。 该结构信息对于预测蛋白质的芳族异戊烯基转移酶活性是有用的。