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公开(公告)号:US20140235469A1
公开(公告)日:2014-08-21
申请号:US14064709
申请日:2013-10-28
申请人: Jeffrey SHELTON , Kevin KELNAR , Stephanie VOLZ , Alex ADAI , David BROWN
发明人: Jeffrey SHELTON , Kevin KELNAR , Stephanie VOLZ , Alex ADAI , David BROWN
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , C12Q2600/112 , C12Q2600/16 , C12Q2600/178
摘要: This application describes miRNAs that may be used as serum or plasma biomarkers for characterizing prostate disease in a patient. These miRNA biomarkers may be used alone or in combination with other markers for the diagnosis, prognosis, or monitoring of diseases such as prostate cancer.
摘要翻译: 该应用描述了可用作血清或血浆生物标志物的miRNA,用于表征患者中的前列腺疾病。 这些miRNA生物标志物可以单独使用或与其它标志物组合使用,用于诊断,预后或监测前列腺癌等疾病。
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公开(公告)号:US20110053158A1
公开(公告)日:2011-03-03
申请号:US12870245
申请日:2010-08-27
申请人: Elizabeth MAMBO , David Brown , Alex T. Adai , Tiffany Sanford , Stephanie Volz , Ashish Choudhary
发明人: Elizabeth MAMBO , David Brown , Alex T. Adai , Tiffany Sanford , Stephanie Volz , Ashish Choudhary
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6883 , C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178
摘要: This application describes miRNAs that may be used as serum or plasma biomarkers for characterizing lung disease in a patient. These miRNA biomarkers may be used alone or in combination with other markers for the diagnosis, prognosis, or monitoring of diseases such as lung cancer.
摘要翻译: 该应用描述了可用作血清或血浆生物标志物的miRNA,用于表征患者的肺部疾病。 这些miRNA生物标志物可以单独使用或与其他标志物组合使用,用于诊断,预后或监测诸如肺癌的疾病。
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公开(公告)号:US08597892B2
公开(公告)日:2013-12-03
申请号:US12785216
申请日:2010-05-21
申请人: Jeffrey Shelton , Kevin Kelnar , Stephanie Volz , Alex Adai , David Brown
发明人: Jeffrey Shelton , Kevin Kelnar , Stephanie Volz , Alex Adai , David Brown
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , C12Q2600/112 , C12Q2600/16 , C12Q2600/178
摘要: This application describes miRNAs that may be used as serum or plasma biomarkers for characterizing prostate disease in a patient. These miRNA biomarkers may be used alone or in combination with other markers for the diagnosis, prognosis, or monitoring of diseases such as prostate cancer.
摘要翻译: 该应用描述了可用作血清或血浆生物标志物的miRNA,用于表征患者中的前列腺疾病。 这些miRNA生物标志物可以单独使用或与其它标志物组合使用,用于诊断,预后或监测前列腺癌等疾病。
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公开(公告)号:US20100297652A1
公开(公告)日:2010-11-25
申请号:US12785216
申请日:2010-05-21
申请人: Jeffrey Shelton , Kevin Kelnar , Stephanie Volz , Alex Adai , David Brown
发明人: Jeffrey Shelton , Kevin Kelnar , Stephanie Volz , Alex Adai , David Brown
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , C12Q2600/112 , C12Q2600/16 , C12Q2600/178
摘要: This application describes miRNAs that may be used as serum or plasma biomarkers for characterizing prostate disease in a patient. These miRNA biomarkers may be used alone or in combination with other markers for the diagnosis, prognosis, or monitoring of diseases such as prostate cancer.
摘要翻译: 该应用描述了可用作血清或血浆生物标志物的miRNA,用于表征患者中的前列腺疾病。 这些miRNA生物标志物可以单独使用或与其它标志物组合使用,用于诊断,预后或监测前列腺癌等疾病。
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公开(公告)号:US08735074B2
公开(公告)日:2014-05-27
申请号:US12870245
申请日:2010-08-27
申请人: Elizabeth Mambo , David Brown , Alex T. Adai , Tiffany Sanford , Stephanie Volz , Ashish Choudhary
发明人: Elizabeth Mambo , David Brown , Alex T. Adai , Tiffany Sanford , Stephanie Volz , Ashish Choudhary
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6883 , C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178
摘要: This application describes miRNAs that may be used as serum or plasma biomarkers for characterizing lung disease in a patient. These miRNA biomarkers may be used alone or in combination with other markers for the diagnosis, prognosis, or monitoring of diseases such as lung cancer.
摘要翻译: 该应用描述了可用作血清或血浆生物标志物的miRNA,用于表征患者的肺部疾病。 这些miRNA生物标志物可以单独使用或与其他标志物组合使用,用于诊断,预后或监测诸如肺癌的疾病。
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公开(公告)号:US20100179213A1
公开(公告)日:2010-07-15
申请号:US12616616
申请日:2009-11-11
申请人: Lubna Patrawala , Dean G. Tang , Kevin Kelnar , Jason Wiggins , Stephanie Volz , Jeffrey Shelton , Can Liu , Andreas G. Bader , David Brown
发明人: Lubna Patrawala , Dean G. Tang , Kevin Kelnar , Jason Wiggins , Stephanie Volz , Jeffrey Shelton , Can Liu , Andreas G. Bader , David Brown
IPC分类号: A61K31/7088 , A61P35/04 , C12Q1/68
CPC分类号: C12N15/113 , C12N15/1131 , C12N2310/14 , C12N2310/141
摘要: The present invention concerns methods and compositions for treating a patient having, suspected of having, or at risk of developing cancer by targeting cancer stem cells.
摘要翻译: 本发明涉及通过靶向癌症干细胞来治疗患有怀疑具有或具有发展癌症风险的患者的方法和组合物。
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