-
公开(公告)号：US20120143286A1
公开(公告)日：2012-06-07
申请号：US13306745
申请日：2011-11-29
IPC分类号： A61N1/372
CPC分类号： A61N1/37282 , A61N1/0556 , A61N1/36132 , A61N1/3615 , A61N1/36178 , A61N1/36185 , A61N1/37252
摘要： According to an embodiment of a method performed by an implantable medical device to deliver a neural stimulation therapy to a patient, a lower dose of the neural stimulation therapy is delivered to the patient. The dose of the neural stimulation therapy is automatically increased from the lower dose to a higher dose, and the higher dose of the neural stimulation therapy is delivered to the patient. A trigger that is controlled by the patient is detected, and the dose of the neural stimulation therapy is automatically returned from the higher dose back to the lower dose in response to detecting the trigger.
摘要翻译： 根据由可植入医疗装置执行以向患者递送神经刺激疗法的方法的实施例，将较低剂量的神经刺激疗法递送给患者。 神经刺激治疗的剂量自动从较低剂量增加到较高剂量，而较高剂量的神经刺激疗法则传递给患者。 检测由患者控制的触发器，并且响应于检测到触发，神经刺激治疗的剂量自动从较高剂量返回到较低剂量。
-
2.发明授权
公开(公告)号：US5468254A
公开(公告)日：1995-11-21
申请号：US97463
申请日：1993-07-26
申请人： Stephen J. Hahn , David K. Swanson
发明人： Stephen J. Hahn , David K. Swanson
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/3906
摘要： A method and apparatus for converting an arrhythmia of a heart using a biphasic truncated exponential waveform wherein the first phase is of shorter duration than the second phase.
摘要翻译： 一种使用双相截短指数波形转换心脏心律失常的方法和装置，其中第一阶段的持续时间比第二阶段短。
-
公开(公告)号：US5230337A
公开(公告)日：1993-07-27
申请号：US912950
申请日：1992-07-14
IPC分类号： A61N1/05
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
摘要翻译： 用于除颤的可植入电极由多个电极段形成。 每个段都相对长而窄。 电极段可以彼此平行和间隔至少十倍于标称宽度的距离，每个段的一端安装到将电极耦合到除颤脉冲发生器的导电引线的横向远端部分。 或者，片段可以从公共接头向外分支或辐射。 在另一种布置中，电极段是在来自脉冲发生器的引线的远端处的单个导电路径的部分，其布置成螺旋构造或蛇形结构，其可以并排并排隔离电极段。 电极段可以由具有溅射的铂外层或不锈钢管中的银芯的钛带或电线形式的复合导体形成，铂层形成在管上。 电极是高度依从性的，但可以为除颤提供大的有效区域，使得能够在心脏外侧皮下植入心脏两侧的两个电极的经胸部脉冲排列。
-
4.发明授权Method and apparatus for adaptive control of neurostimulation using cardiac restitution 有权使用心脏恢复法进行神经刺激的自适应控制的方法和装置公开(公告)号：US09126045B2
公开(公告)日：2015-09-08
申请号：US13586503
申请日：2012-08-15
CPC分类号： A61N1/36114 , A61N1/36139
摘要： A neurostimulation system measures a cardiac parameter at various cardiac intervals and analyzes its restitution, including computing a restitution slope being a rate of change of the restitution parameter with respect to change in the cardiac interval. In various embodiments, the system uses the restitution slope to provide for adaptive control of neurostimulation. In various embodiments, one or more cardiac parameters such as action potential duration (APD), conduction velocity (CV), QT interval (QT), and/or T-wave morphology (TM) parameter are measured and analyzed for restitution of each parameter, which is then used to control the delivery of the neurostimulation.
摘要翻译： 神经刺激系统以各种心脏间隔测量心脏参数并分析其恢复，包括计算相对于心脏间隔变化的恢复参数的变化率的恢复斜率。 在各种实施例中，系统使用恢复斜率来提供神经刺激的自适应控制。 在各种实施例中，测量并分析一个或多个心脏参数，例如动作电位持续时间（APD），传导速度（CV），QT间期（QT）和/或T波形态（TM）参数，以分析每个参数的恢复 ，然后用于控制神经刺激的递送。
-
公开(公告)号：US20130158621A1
公开(公告)日：2013-06-20
申请号：US13716810
申请日：2012-12-17
申请人： Jiang Ding , Allan C. Shuros , Dan Li , Yinghong Yu , Stephen J. Hahn
发明人： Jiang Ding , Allan C. Shuros , Dan Li , Yinghong Yu , Stephen J. Hahn
IPC分类号： A61N1/365
CPC分类号： A61N1/36592 , A61B5/02152 , A61B5/0464 , A61B5/0468 , A61N1/365 , A61N1/37 , A61N1/371
摘要： Ectopic cardiac activity can be detected, such as in the absence of a diagnosed tachyarrhythmia episode. In response to the detected ectopic activity, electrostimulation can be provided to a para-Hisian region, such as to activate natural cardiac contraction mechanisms or to interrupt re-entrant cardiac activity. Subsequent ectopic cardiac activity can be detected, and subsequent electrostimulation can be provided to the para-Hisian region, such as according to one or more adjustable electrostimulation parameters.
摘要翻译： 可以检测异位心脏活动，例如在没有诊断的快速性心律失常发作时。 响应于检测到的异位活动，可以向对等神经区域提供电刺激，例如激活自然心脏收缩机制或中断再入心脏活动。 可以检测随后的异位心脏活动，并且可以根据一个或多个可调节的电刺激参数来向对 - Hisian区域提供随后的电刺激。
-
公开(公告)号：US06275730B1
公开(公告)日：2001-08-14
申请号：US09390442
申请日：1999-09-07
IPC分类号： A61N139
CPC分类号： A61N1/3937 , A61N1/3918 , A61N1/3943
摘要： An implantable system for the cardioversion of the heart of a patient in need of such treatment comprises a plurality of primary electrodes, a power supply, and a control circuit. Preferably, at least one auxiliary electrode is also included. The plurality of primary electrodes are configured for delivering a cardiversion pulse along a predetermined current pathway in a first portion of the heart, the current pathway defining a weak field area in a second portion of the heart.
摘要翻译： 用于需要这种治疗的患者的心脏的心脏复律的可植入系统包括多个初级电极，电源和控制电路。 优选地，还包括至少一个辅助电极。 多个主电极被配置用于沿着心脏的第一部分中的预定电流通路输送引导脉冲，该电流通路在心脏的第二部分中限定弱磁场区域。
-
7.发明授权
公开(公告)号：US5978705A
公开(公告)日：1999-11-02
申请号：US39143
申请日：1998-03-13
CPC分类号： A61N1/3937 , A61N1/3918 , A61N1/3943
摘要： An implantable system for the defibrillation or cardioversion of the heart of a patient in need of such treatment comprises a plurality of primary electrodes, a power supply, and a control circuit. Preferably, at least one auxiliary electrode is also included. The plurality of primary electrodes are configured for delivering a defibrillation pulse along a predetermined current pathway in a first portion of the heart, the current pathway defining a weak field area in a second portion of the heart. The at least one auxiliary electrode is configured for delivering an auxiliary pulse to the a portion of the heart where the primary shock field intensity is at or near a minimum. The control circuit is operatively associated with the primary electrodes, the auxiliary electrode, and the power supply, with the control circuit configured for delivering a cardioversion sequence comprising an auxiliary pulse sufficient to induce a cessation of propagation in the weak field area through the auxiliary electrode, followed by a defibrillation pulse through the primary electrodes delivered during the cessation of propagation in the weak field area.
摘要翻译： 用于需要这种治疗的患者的心脏的除颤或心脏复律的可植入系统包括多个初级电极，电源和控制电路。 优选地，还包括至少一个辅助电极。 多个主电极被配置用于沿心脏的第一部分中的预定电流通路输送除颤脉冲，该电流通路在心脏的第二部分中限定弱磁场区域。 所述至少一个辅助电极被配置为将辅助脉冲传送到心脏的一部分，其中主要的冲击电场强度处于或接近最小值。 所述控制电路与所述主电极，所述辅助电极和所述电源可操作地相关联，所述控制电路被配置用于传送包括辅助脉冲的复律序列，所述辅助脉冲足以引起通过所述辅助电极在所述弱磁场区域中的传播停止 ，然后通过在弱磁场区域中传播停止期间传递的主电极的除颤脉冲。
-
公开(公告)号：US5342407A
公开(公告)日：1994-08-30
申请号：US912924
申请日：1992-07-13
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
摘要翻译： 用于除颤的可植入电极由多个电极段形成。 每个段都相对长而窄。 电极段可以彼此平行和间隔至少十倍于标称宽度的距离，每个段的一端安装到将电极耦合到除颤脉冲发生器的导电引线的横向远端部分。 或者，片段可以从公共接头向外分支或辐射。 在另一种布置中，电极段是在来自脉冲发生器的引线的远端处的单个导电路径的部分，其布置成螺旋构造或蛇形结构，其可以并排并排隔离电极段。 电极段可以由具有溅射的铂外层或不锈钢管中的银芯的钛带或电线形式的复合导体形成，铂层形成在管上。 电极是高度依从性的，但可以为除颤提供大的有效区域，使得能够在心脏外侧皮下植入心脏两侧的两个电极的经胸部脉冲排列。
-
公开(公告)号：US5203348A
公开(公告)日：1993-04-20
申请号：US533886
申请日：1990-06-06
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
-
公开(公告)号：US09937353B2
公开(公告)日：2018-04-10
申请号：US13306745
申请日：2011-11-29
CPC分类号： A61N1/37282 , A61N1/0556 , A61N1/36132 , A61N1/3615 , A61N1/36178 , A61N1/36185 , A61N1/37252
摘要： According to an embodiment of a method performed by an implantable medical device to deliver a neural stimulation therapy to a patient, a lower dose of the neural stimulation therapy is delivered to the patient. The dose of the neural stimulation therapy is automatically increased from the lower dose to a higher dose, and the higher dose of the neural stimulation therapy is delivered to the patient. A trigger that is controlled by the patient is detected, and the dose of the neural stimulation therapy is automatically returned from the higher dose back to the lower dose in response to detecting the trigger.
-
-
-
-
-
-
-
-
-
搜索结果
26 条记录 (耗时 0.041 秒)