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公开(公告)号：US5603732A
公开(公告)日：1997-02-18
申请号：US554577
申请日：1995-11-06
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
摘要翻译： 用于除颤的可植入电极由多个电极段形成。 每个段都相对长而窄。 电极段可以彼此平行和间隔至少十倍于标称宽度的距离，每个段的一端安装到将电极耦合到除颤脉冲发生器的导电引线的横向远端部分。 或者，片段可以从公共接头向外分支或辐射。 在另一种布置中，电极段是在来自脉冲发生器的引线的远端处的单个导电路径的部分，其布置成螺旋构造或蛇形结构，其可以并排并排隔离电极段。 电极段可以由具有溅射的铂外层或不锈钢管中的银芯的钛带或电线形式的复合导体形成，铂层形成在管上。 电极是高度依从性的，但可以为除颤提供大的有效区域，使得能够在心脏的相对侧上的两个电极的经胸部脉冲排列皮下植入胸部区域。
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公开(公告)号：US5545202A
公开(公告)日：1996-08-13
申请号：US285802
申请日：1994-08-04
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
摘要翻译： 用于除颤的可植入电极由多个电极段形成。 每个段都相对长而窄。 电极段可以彼此平行和间隔至少十倍于标称宽度的距离，每个段的一端安装到将电极耦合到除颤脉冲发生器的导电引线的横向远端部分。 或者，片段可以从公共接头向外分支或辐射。 在另一种布置中，电极段是在来自脉冲发生器的引线的远端处的单个导电路径的部分，其布置成螺旋构造或蛇形结构，其可以并排并排隔离电极段。 电极段可以由具有溅射的铂外层或不锈钢管中的银芯的钛带或电线形式的复合导体形成，铂层形成在管上。 电极是高度依从性的，但可以为除颤提供大的有效区域，使得能够在心脏外侧皮下植入心脏两侧的两个电极的经胸部脉冲排列。
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公开(公告)号：US5230337A
公开(公告)日：1993-07-27
申请号：US912950
申请日：1992-07-14
IPC分类号： A61N1/05
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
摘要翻译： 用于除颤的可植入电极由多个电极段形成。 每个段都相对长而窄。 电极段可以彼此平行和间隔至少十倍于标称宽度的距离，每个段的一端安装到将电极耦合到除颤脉冲发生器的导电引线的横向远端部分。 或者，片段可以从公共接头向外分支或辐射。 在另一种布置中，电极段是在来自脉冲发生器的引线的远端处的单个导电路径的部分，其布置成螺旋构造或蛇形结构，其可以并排并排隔离电极段。 电极段可以由具有溅射的铂外层或不锈钢管中的银芯的钛带或电线形式的复合导体形成，铂层形成在管上。 电极是高度依从性的，但可以为除颤提供大的有效区域，使得能够在心脏外侧皮下植入心脏两侧的两个电极的经胸部脉冲排列。
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公开(公告)号：US5360442A
公开(公告)日：1994-11-01
申请号：US967361
申请日：1993-01-04
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
摘要翻译： 用于除颤的可植入电极由多个电极段形成。 每个段都相对长而窄。 电极段可以彼此平行和间隔至少十倍于标称宽度的距离，每个段的一端安装到将电极耦合到除颤脉冲发生器的导电引线的横向远端部分。 或者，片段可以从公共接头向外分支或辐射。 在另一种布置中，电极段是在来自脉冲发生器的引线的远端处的单个导电路径的部分，其布置成螺旋构造或蛇形结构，其可以并排并排隔离电极段。 电极段可以由具有溅射的铂外层或不锈钢管中的银芯的钛带或电线形式的复合导体形成，铂层形成在管上。 电极是高度依从性的，但可以为除颤提供大的有效区域，使得能够在心脏的相对侧上的两个电极的经胸部脉冲排列皮下植入胸部区域。
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公开(公告)号：US5342407A
公开(公告)日：1994-08-30
申请号：US912924
申请日：1992-07-13
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
摘要翻译： 用于除颤的可植入电极由多个电极段形成。 每个段都相对长而窄。 电极段可以彼此平行和间隔至少十倍于标称宽度的距离，每个段的一端安装到将电极耦合到除颤脉冲发生器的导电引线的横向远端部分。 或者，片段可以从公共接头向外分支或辐射。 在另一种布置中，电极段是在来自脉冲发生器的引线的远端处的单个导电路径的部分，其布置成螺旋构造或蛇形结构，其可以并排并排隔离电极段。 电极段可以由具有溅射的铂外层或不锈钢管中的银芯的钛带或电线形式的复合导体形成，铂层形成在管上。 电极是高度依从性的，但可以为除颤提供大的有效区域，使得能够在心脏外侧皮下植入心脏两侧的两个电极的经胸部脉冲排列。
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公开(公告)号：US5203348A
公开(公告)日：1993-04-20
申请号：US533886
申请日：1990-06-06
CPC分类号： A61N1/05
摘要： Implantable electrodes for defibrillation are formed of pluralities of electrode segments. Each of the segments is relatively long and narrow. The electrode segments can be parallel and spaced apart from one another a distance at least ten times the nominal width, with one end of each segment mounted to a transverse distal portion of an electrically conductive lead coupling the electrode to a defibrillation pulse generator. Alternatively, segments can branch or radiate outwardly from a common junction. In yet another arrangement, electrode segments are portions of a single conductive path at the distal end of a lead from a pulse generator, arranged in either a spiral configuration or a serpentine configuration which can align electrode segments side by side, parallel and spaced apart. The electrode segments can be formed of composite conductors in the form of titanium ribbons or wires with a sputtered outer layer of platinum, or a silver core in a stainless steel tube, with a platinum layer formed onto the tube. The electrodes are highly compliant yet can provide large effective areas for defibrillation, enabling a transthoracic pulsing arrangement of two electrodes on opposite sides of the heart, implanted subcutaneously outside of the thoracic region.
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公开(公告)号：US5090422A
公开(公告)日：1992-02-25
申请号：US511068
申请日：1990-04-19
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0587
摘要： A novel method and apparatus for isolating and anchoring an implantable electrically stimulating probe such as a defibrillator patch electrode for use with an automatic cardioverter/defibrillator is disclosed in which a porous bio-compatible coating or enclosure covers and isolates the electrode in a way which allows electrical conductivity via bodily fluid which passes through but separates the electrode from the adjacent tissue in the manner of dissection plane which substantially prevents tissue ingrowth. The coating or enclosure controls the minimum separation distance from the closest tissue and which reduces the local current density applied to adjacent tissue when the electrode is pulsed. The system includes a provision for attaching the enclosure means to internal bodily tissue.
摘要翻译： 公开了用于分离和锚定可植入电刺激探针（例如用于自动心律转复除颤器的除颤器贴片电极）的新颖方法和装置，其中多孔生物相容性涂层或外壳以允许的方式覆盖并隔离电极 穿过体液的导电性通过基本上防止组织向内生长的解剖平面的方式将电极与相邻组织隔开。 涂层或外壳控制距离最近的组织的最小间隔距离，并且当电极被脉冲时减小施加到相邻组织的局部电流密度。 该系统包括用于将外壳装置附接到内部身体组织的装置。
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公开(公告)号：US06212434B1
公开(公告)日：2001-04-03
申请号：US09120824
申请日：1998-07-22
申请人： Avram Scheiner , William Hsu , David M. Flynn , Qingsheng Zhu , John E. Heil , Ronald W. Heil, Jr. , Curtis C. Lindstrom , Robert S. Booker, III , Yayun Lin , Peter T. Kelley , Jay A. Warren , Gerrard M. Carlson , Carol Werlein , Aaron W. Janke , Mary Lee Cole , Jeffrey T. Bartig , Gary W. Goebel , Douglas A. Heitkamp , Randall M. Peterfeso
发明人： Avram Scheiner , William Hsu , David M. Flynn , Qingsheng Zhu , John E. Heil , Ronald W. Heil, Jr. , Curtis C. Lindstrom , Robert S. Booker, III , Yayun Lin , Peter T. Kelley , Jay A. Warren , Gerrard M. Carlson , Carol Werlein , Aaron W. Janke , Mary Lee Cole , Jeffrey T. Bartig , Gary W. Goebel , Douglas A. Heitkamp , Randall M. Peterfeso
IPC分类号： A61N105
CPC分类号： A61N1/0573 , A61N1/0563
摘要： A single-pass endocardial lead electrode adapted for implantation in, on or about the heart and for connection to a system for monitoring or stimulating cardiac activity includes a lead body which is adapted for implantation within a single chamber of the heart, or multiple chambers of the heart. The lead includes a first distal end electrode which has a first electrical conducting surface. The lead body also has a second electrode which has a second electrical conducting surface. The first and second electrodes are either passively or actively attached to the wall of the heart. The lead body also includes a curved portion which facilitates the positioning of the second electrode. The main lead body alternatively includes a recess into which an atrial lead body and an active fixation element attached to one end can travel from a recessed position to a position for fixation to the wall of the heart. The active fixation element can also be moved by turning the terminal pin. The lead body can also include multiple legs, each leg carrying an electrode. The lead is attached to a pulse generator for producing pulses to the multiple sites within the heart. A movement assembly for advancing a helix is also included within the legs and comprises an externally threaded collar which engages with an internally threaded housing or housing insert. The lead further includes a helical tip which has high impedance. The electrode has at least one features of the group: the helix having a coating of an insulating material on its surface, the helix having its surface beyond the distal end of the electrode and the distal end of the electrode having a porous conductive surface at a base of the helix, a porous conductive element at a base of the helix, and a porous conductive element at the end of the electrode having an insulating coating cover from 5-95% of the surface of the porous conductive element. The porous element may further provide a guiding mechanism for the helix as it travels out of the electrode for securing the electrode to the heart.
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公开(公告)号：US06584363B2
公开(公告)日：2003-06-24
申请号：US09906571
申请日：2001-07-16
IPC分类号： A61N105
CPC分类号： A61N1/0568 , A61N1/056
摘要： A cardiac rhythm management system provides an endocardial cardiac rhythm management lead with an at least partially dissolvable coating at least partially on insulating portions of the lead body at or near its distal end. Upon dissolution, the coating promotes tissue ingrowth to secure the lead in place within fragile vascular structures or elsewhere. Dissolution of one such coating releases a therapeutic agent, such as a steroid that modifies the fibrotic scar tissue content of tissue ingrowth, such that the resulting bond between the tissue and the lead is weak, so that the lead can be easily extracted if desired. One such lead includes an insulating elongate body carrying at least. The lead also includes an at least partially dissolvable coating on an insulating portion of the peripheral distal lead surface. The coating provides one or more of a rough surface, a porous surface, or a swollen surface after being exposed to an aqueous substance.
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公开(公告)号：US06408213B1
公开(公告)日：2002-06-18
申请号：US09407364
申请日：1999-09-29
IPC分类号： A61N100
CPC分类号： A61N1/0563 , A61N2001/0585
摘要： A cardiac lead designed for implantation in the vasculature of the left side of the heart comprising a flexible lead body having a central lumen, a removable terminal pin, electrodes electrically coupled to the removable terminal pin, a mechanism for securing the electrodes in the proper position in the vasculature and a mechanism for sealing the central lumen after implantation to prevent body fluids from invading the lumen. The cardiac lead can be implanted or explanted using either a guidewire, a guide catheter or both.
摘要翻译： 设计用于植入在心脏左侧脉管系统中的心脏引线，包括具有中心腔的柔性引线体，可移除端子引脚，电耦合到可移除端子引脚的电极，用于将电极固定在适当位置的机构 在脉管系统中以及用于在植入后密封中央腔的机构，以防止体液侵入内腔。 可以使用导丝，引导导管或两者将植入或移植心脏引线。
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