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公开(公告)号：US20210196320A1
公开(公告)日：2021-07-01
申请号：US17192329
申请日：2021-03-04
申请人： James S. GAMMIE , Philip J. HAARSTAD , David BLAESER , Ryan BAUER , Stephen ROLLER , Rachael QUINN , Chetan PASRIJA , Edwin HLAVKA
发明人： James S. GAMMIE , Philip J. HAARSTAD , David BLAESER , Ryan BAUER , Stephen ROLLER , Rachael QUINN , Chetan PASRIJA , Edwin HLAVKA
IPC分类号： A61B17/34
摘要： In some embodiments, a method includes a shaft having a side catheter guide attached thereto via a guide coupler into an inferior vena cava and a superior vena cava such that the guide coupler is disposed in a right atrium, and applying a distal force to a proximal portion of the side catheter guide such that a distal end of the side catheter guide deflects laterally about the guide coupler towards a septum. The method further includes extending a side catheter that is disposed within the side catheter guide distally from the side catheter guide towards and into contact with the septum. The method further includes, with the side catheter in contact with the septum, extending a septum penetrator that is slidably disposed within the side catheter distally from the side catheter such that the septum penetrator pierces the septum.
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2.发明申请公开(公告)号：US20120193289A1
公开(公告)日：2012-08-02
申请号：US13015363
申请日：2011-01-27
申请人： Patrick Cloutier , Robert Olsen , Stephen Roller , Chris Plott , Al McLevish , Ming Li , Michael Laxen , John Knoll , Gregory Hake
发明人： Patrick Cloutier , Robert Olsen , Stephen Roller , Chris Plott , Al McLevish , Ming Li , Michael Laxen , John Knoll , Gregory Hake
CPC分类号： A61M1/1698 , A61M2206/16 , A61M2206/20
摘要： An apparatus for de-aering, oxygenating and controlling a temperature of blood in an extracorporeal blood circuit. The apparatus includes a housing, a manifold body, a heat exchanger, and an oxygenator. A blood inlet tangentially directs blood into a first chamber of the housing. The manifold body is disposed in a second chamber, and includes a core and a plurality of vanes that define channels. The heat exchanger is arranged around the manifold body, and the oxygenator around the heat exchanger. The channels are open to the heat exchanger. An established blood flow path includes rotational flow within the first chamber to separate air from the blood, generally longitudinal flow from the first chamber and along the channels, and generally radial flow through the heat exchanger and the oxygenator. With this construction, gross air removal occurs prior to the blood passing through the heat exchanger and oxygenator.
摘要翻译： 一种用于在体外血液回路中去血，氧合和控制血液温度的装置。 该装置包括壳体，歧管体，热交换器和氧合器。 血液入口切向地将血液引导到壳体的第一腔室中。 歧管主体设置在第二室中，并且包括限定通道的芯和多个叶片。 热交换器布置在歧管主体周围，并且热交换器周围设置有氧合器。 通道通向热交换器。 已建立的血流路径包括在第一室内的旋转流动，以从血液中分离空气，大体上来自第一腔室的纵向流动并且沿着通道，并且通常径向流过热交换器和氧合器。 利用这种结构，在血液通过热交换器和充氧器之前，总的空气除去发生。
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3.发明授权Dual outlet oxygenator for treating blood in an extracorporeal blood circuit 有权双出口氧合器，用于治疗体外血液回路中的血液公开(公告)号：US08795591B2
公开(公告)日：2014-08-05
申请号：US13397446
申请日：2012-02-15
CPC分类号： A61M1/1698 , A61M1/36 , A61M2209/082
摘要： An apparatus for oxygenating blood including a housing and an oxygenator bundle. The housing defines a primary chamber, a blood inlet port open to the primary chamber, and a blood outlet region. The outlet region includes a blood outlet port, an outlet chamber open to the outlet port, and a partition. The partition establishes spaced apart, first and second passageways from the primary chamber to the outlet chamber. The oxygenator bundle is disposed within the primary chamber. A blood flow path is formed from the blood inlet port, through the oxygenator bundle and to the blood outlet port, and includes first and second outlet flow paths within the outlet chamber via the first and second passageways, respectively. The first and second outlet blood flow paths merge at the blood outlet port. A dual port blood outlet is created, increasing mixing of blood immediately upstream of the outlet port.
摘要翻译： 一种用于使血液充氧的装置，包括壳体和充氧器束。 壳体限定主室，通向主腔室的血液入口和血液出口区域。 出口区域包括血液出口，通向出口的出口腔和分隔件。 分隔件形成从主室到出口室的间隔开的第一和第二通道。 充氧器束设置在主室内。 血液流路由血液入口通过充氧器束和血液出口形成，并且分别经由第一和第二通道包括出口室内的第一和第二出口流动路径。 第一和第二出血血流通道在血液出口处合并。 产生双口血液出口，增加了紧靠出口端上游的血液混合。
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4.发明申请公开(公告)号：US20140050617A9
公开(公告)日：2014-02-20
申请号：US13397446
申请日：2012-02-15
IPC分类号： A61M1/32
CPC分类号： A61M1/1698 , A61M1/36 , A61M2209/082
摘要： An apparatus for oxygenating blood including a housing and an oxygenator bundle. The housing defines a primary chamber, a blood inlet port open to the primary chamber, and a blood outlet region. The outlet region includes a blood outlet port, an outlet chamber open to the outlet port, and a partition. The partition establishes spaced apart, first and second passageways from the primary chamber to the outlet chamber. The oxygenator bundle is disposed within the primary chamber. A blood flow path is formed from the blood inlet port, through the oxygenator bundle and to the blood outlet port, and includes first and second outlet flow paths within the outlet chamber via the first and second passageways, respectively. The first and second outlet blood flow paths merge at the blood outlet port. A dual port blood outlet is created, increasing mixing of blood immediately upstream of the outlet port.
摘要翻译： 一种用于使血液充氧的装置，包括壳体和充氧器束。 壳体限定主室，通向主腔室的血液入口和血液出口区域。 出口区域包括血液出口，通向出口的出口腔和分隔件。 分隔件形成从主室到出口室的间隔开的第一和第二通道。 充氧器束设置在主室内。 血液流路由血液入口通过充氧器束和血液出口形成，并且分别经由第一和第二通道包括出口室内的第一和第二出口流动路径。 第一和第二出血血流通道在血液出口处合并。 产生双口血液出口，增加了紧靠出口端上游的血液混合。
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5.发明授权公开(公告)号：US08518259B2
公开(公告)日：2013-08-27
申请号：US13015363
申请日：2011-01-27
申请人： Patrick Cloutier , Robert Olsen , Stephen Roller , Chris Plott , Al McLevish , Ming Li , Michael Laxen , John Knoll , Gregory Hake
发明人： Patrick Cloutier , Robert Olsen , Stephen Roller , Chris Plott , Al McLevish , Ming Li , Michael Laxen , John Knoll , Gregory Hake
CPC分类号： A61M1/1698 , A61M2206/16 , A61M2206/20
摘要： An apparatus for de-aering, oxygenating and controlling a temperature of blood in an extracorporeal blood circuit. The apparatus includes a housing, a manifold body, a heat exchanger, and an oxygenator. A blood inlet tangentially directs blood into a first chamber of the housing. The manifold body is disposed in a second chamber, and includes a core and a plurality of vanes that define channels. The heat exchanger is arranged around the manifold body, and the oxygenator around the heat exchanger. The channels are open to the heat exchanger. An established blood flow path includes rotational flow within the first chamber to separate air from the blood, generally longitudinal flow from the first chamber and along the channels, and generally radial flow through the heat exchanger and the oxygenator. With this construction, gross air removal occurs prior to the blood passing through the heat exchanger and oxygenator.
摘要翻译： 一种用于在体外血液回路中去血，氧合和控制血液温度的装置。 该装置包括壳体，歧管体，热交换器和氧合器。 血液入口切向地将血液引导到壳体的第一腔室中。 歧管主体设置在第二室中，并且包括限定通道的芯和多个叶片。 热交换器布置在歧管主体周围，并且热交换器周围设置有氧合器。 通道通向热交换器。 已建立的血流路径包括在第一室内的旋转流动，以从血液中分离空气，大体上来自第一腔室的纵向流动并且沿着通道，并且通常径向流过热交换器和氧合器。 利用这种结构，在血液通过热交换器和充氧器之前，总的空气除去发生。
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公开(公告)号：US20120197363A1
公开(公告)日：2012-08-02
申请号：US13015398
申请日：2011-01-27
申请人： Patrick Cloutier , Robert Olsen , Stephen Roller , Chris Plott , Al McLevish , Ming Li , Michael Laxen , John Knoll , Gregory Hake
发明人： Patrick Cloutier , Robert Olsen , Stephen Roller , Chris Plott , Al McLevish , Ming Li , Michael Laxen , John Knoll , Gregory Hake
CPC分类号： F28D15/046 , A61M1/1698 , A61M1/367 , A61M1/369 , B01D63/025 , B01D2313/38 , B29C53/083 , B29L2031/18 , Y10T29/49353
摘要： A capillary tube bundle sub-assembly for use in an extracorporeal heat exchanger includes a continuous capillary tubing wound about a core to define a plurality of capillary layers each including a plurality of capillary segments. The capillary segments each define opposing terminal ends adjacent opposing ends of the core. The capillary segments of each layer are circumferentially aligned relative to an axis of the core, with each successive layer being radially outward of an immediately preceding layer. The capillary segments are non-parallel with the axis, spiraling partially about the axis in extension between the opposing terminal ends. Each capillary segment forms less than one complete revolution (i.e., winds less than 360°). The segments within each layer are substantially parallel with one another; however, an orientation of the segments differs from layer-to-layer such as by pitch or angle.
摘要翻译： 用于体外热交换器的毛细管束子组件包括围绕芯缠绕的连续毛细管，以限定多个毛细管层，每个毛细管层包括多个毛细管段。 毛细管段各自限定与芯的相对端相邻的相对的末端。 每个层的毛细管段相对于芯的轴线周向对准，每个连续层在紧邻的前一层的径向外侧。 毛细管段与轴不平行，部分地围绕相对端部之间延伸的轴线螺旋形。 每个毛细管段形成少于一个完整的旋转（即，风小于360°）。 每个层内的段基本上彼此平行; 然而，片段的取向不同于层间层，例如通过间距或角度。
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7.发明申请公开(公告)号：US20130209314A1
公开(公告)日：2013-08-15
申请号：US13397446
申请日：2012-02-15
IPC分类号： A61M1/32
CPC分类号： A61M1/1698 , A61M1/36 , A61M2209/082
摘要： An apparatus for oxygenating blood including a housing and an oxygenator bundle. The housing defines a primary chamber, a blood inlet port open to the primary chamber, and a blood outlet region. The outlet region includes a blood outlet port, an outlet chamber open to the outlet port, and a partition. The partition establishes spaced apart, first and second passageways from the primary chamber to the outlet chamber. The oxygenator bundle is disposed within the primary chamber. A blood flow path is formed from the blood inlet port, through the oxygenator bundle and to the blood outlet port, and includes first and second outlet flow paths within the outlet chamber via the first and second passageways, respectively. The first and second outlet blood flow paths merge at the blood outlet port. A dual port blood outlet is created, increasing mixing of blood immediately upstream of the outlet port.
摘要翻译： 一种用于使血液充氧的装置，包括壳体和充氧器束。 壳体限定主室，通向主腔室的血液入口和血液出口区域。 出口区域包括血液出口，通向出口的出口腔和分隔件。 分隔件形成从主室到出口室的间隔开的第一和第二通道。 充氧器束设置在主室内。 血液流路由血液入口通过充氧器束和血液出口形成，并且分别经由第一和第二通道包括出口室内的第一和第二出口流动路径。 第一和第二出血血流通道在血液出口处合并。 产生双口血液出口，增加了紧靠出口端上游的血液混合。
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公开(公告)号：US11172960B2
公开(公告)日：2021-11-16
申请号：US17192329
申请日：2021-03-04
申请人： James S. Gammie , Philip J. Haarstad , David Blaeser , Ryan Bauer , Stephen Roller , Rachael Quinn , Chetan Pasrija , Edwin Hlavka
发明人： James S. Gammie , Philip J. Haarstad , David Blaeser , Ryan Bauer , Stephen Roller , Rachael Quinn , Chetan Pasrija , Edwin Hlavka
摘要： In some embodiments, a method includes a shaft having a side catheter guide attached thereto via a guide coupler into an inferior vena cava and a superior vena cava such that the guide coupler is disposed in a right atrium, and applying a distal force to a proximal portion of the side catheter guide such that a distal end of the side catheter guide deflects laterally about the guide coupler towards a septum. The method further includes extending a side catheter that is disposed within the side catheter guide distally from the side catheter guide towards and into contact with the septum. The method further includes, with the side catheter in contact with the septum, extending a septum penetrator that is slidably disposed within the side catheter distally from the side catheter such that the septum penetrator pierces the septum.
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公开(公告)号：US08579845B2
公开(公告)日：2013-11-12
申请号：US13015398
申请日：2011-01-27
申请人： Patrick Cloutier , Robert Olsen , Stephen Roller , Chris Plott , Al McLevish , Ming Li , Michael Laxen , John Knoll , Gregory Hake
发明人： Patrick Cloutier , Robert Olsen , Stephen Roller , Chris Plott , Al McLevish , Ming Li , Michael Laxen , John Knoll , Gregory Hake
CPC分类号： F28D15/046 , A61M1/1698 , A61M1/367 , A61M1/369 , B01D63/025 , B01D2313/38 , B29C53/083 , B29L2031/18 , Y10T29/49353
摘要： A capillary tube bundle sub-assembly for use in an extracorporeal heat exchanger includes a continuous capillary tubing wound about a core to define a plurality of capillary layers each including a plurality of capillary segments. The capillary segments each define opposing terminal ends adjacent opposing ends of the core. The capillary segments of each layer are circumferentially aligned relative to an axis of the core, with each successive layer being radially outward of an immediately preceding layer. The capillary segments are non-parallel with the axis, spiraling partially about the axis in extension between the opposing terminal ends. Each capillary segment forms less than one complete revolution (i.e., winds less than 360°). The segments within each layer are substantially parallel with one another; however, an orientation of the segments differs from layer-to-layer such as by pitch or angle.
摘要翻译： 用于体外热交换器的毛细管束子组件包括围绕芯缠绕的连续毛细管，以限定多个毛细管层，每个毛细管层包括多个毛细管段。 毛细管段各自限定与芯的相对端相邻的相对的末端。 每个层的毛细管段相对于芯的轴线周向对准，每个连续层在紧邻的前一层的径向外侧。 毛细管段与轴不平行，部分地围绕相对端部之间延伸的轴线螺旋形。 每个毛细管段形成少于一个完整的旋转（即，风小于360°）。 每个层内的段基本上彼此平行; 然而，片段的取向不同于层间层，例如通过间距或角度。
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