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公开(公告)号:US08318484B2
公开(公告)日:2012-11-27
申请号:US12617721
申请日:2009-11-12
申请人: Sharon C. Presnell , Andrew Bruce , Shay M. Wallace , Sumana Choudhury , Russell W. Kelley , Manuel J. Jayo , Jessica J. Reinsch , Patricia D. Tatsumi , Timothy A. Bertram , Eric S. Werdin , Oluwatoyin A. Knight , H. Scott Rapoport , Roger M. Ilagan
发明人: Sharon C. Presnell , Andrew Bruce , Shay M. Wallace , Sumana Choudhury , Russell W. Kelley , Manuel J. Jayo , Jessica J. Reinsch , Patricia D. Tatsumi , Timothy A. Bertram , Eric S. Werdin , Oluwatoyin A. Knight , H. Scott Rapoport , Roger M. Ilagan
IPC分类号: C12N5/00
CPC分类号: A61K35/22 , A61K35/12 , C12N5/0686 , C12N2500/02
摘要: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
摘要翻译: 本发明涉及分离的肾细胞,包括产生肾细胞群的管状和促红细胞生成素(EPO),以及分离和培养肾细胞群的方法,以及用细胞群治疗需要的受试者的方法。
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公开(公告)号:US10077442B2
公开(公告)日:2018-09-18
申请号:US13697206
申请日:2011-05-12
申请人: Timothy A. Bertram , Roger M. Ilagan , Russell W. Kelley , Sharon C. Presnell , Sumana Choudhury , Andrew T. Bruce , Christopher W. Genheimer , Bryan R. Cox , Kelly I. Guthrie , Joydeep Basu , Shay M. Wallace , Eric Werdin , Oluwatoyin A. Knight , Namrata D. Sangha , John W. Ludlow , Craig R. Halberstadt , Richard Payne , Neil F. Robins , Darell McCoy , Deepak Jain , Manuel J. Jayo , Elias A. Rivera , Thomas Spencer , Benjamin Watts
发明人: Timothy A. Bertram , Roger M. Ilagan , Russell W. Kelley , Sharon C. Presnell , Sumana Choudhury , Andrew T. Bruce , Christopher W. Genheimer , Bryan R. Cox , Kelly I. Guthrie , Joydeep Basu , Shay M. Wallace , Eric Werdin , Oluwatoyin A. Knight , Namrata D. Sangha , John W. Ludlow , Craig R. Halberstadt , Richard Payne , Neil F. Robins , Darell McCoy , Deepak Jain , Manuel J. Jayo , Elias A. Rivera , Thomas Spencer , Benjamin Watts
IPC分类号: C07H21/02 , C07H21/04 , A61K48/00 , C12N15/113 , C12N5/071 , C12Q1/6883
CPC分类号: C12N15/113 , C12N5/0686 , C12N2310/141 , C12N2320/30 , C12N2320/32 , C12Q1/6883 , C12Q2600/106 , C12Q2600/178
摘要: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
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公开(公告)号:US20110117162A1
公开(公告)日:2011-05-19
申请号:US12617721
申请日:2009-11-12
申请人: Sharon C. Presnell , Andrew Bruce , Shay M. Wallace , Sumana Choudhury , Russell W. Kelley , Manuel J. Jayo , Jessica J. Reinsch , Patricia D. Tatsumi , Timothy A. Bertram , Eric S. Werdin , Oluwatoyin A. Knight , H. Scott Rapoport , Roger M. Ilagan
发明人: Sharon C. Presnell , Andrew Bruce , Shay M. Wallace , Sumana Choudhury , Russell W. Kelley , Manuel J. Jayo , Jessica J. Reinsch , Patricia D. Tatsumi , Timothy A. Bertram , Eric S. Werdin , Oluwatoyin A. Knight , H. Scott Rapoport , Roger M. Ilagan
CPC分类号: A61K35/22 , A61K35/12 , C12N5/0686 , C12N2500/02
摘要: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
摘要翻译: 本发明涉及分离的肾细胞,包括产生肾细胞群的管状和促红细胞生成素(EPO),以及分离和培养肾细胞群的方法,以及用细胞群治疗需要的受试者的方法。
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公开(公告)号:US10030242B2
公开(公告)日:2018-07-24
申请号:US13697206
申请日:2011-05-12
申请人: Timothy A. Bertram , Roger M. Ilagan , Russell W. Kelley , Sharon C. Presnell , Sumana Choudhury , Andrew T. Bruce , Christopher W. Genheimer , Bryan R. Cox , Kelly I. Guthrie , Joydeep Basu , Shay M. Wallace , Eric Werdin , Oluwatoyin A. Knight , Namrata D. Sangha , John W. Ludlow , Craig R. Halberstadt , Richard Payne , Neil F. Robins , Darell McCoy , Deepak Jain , Manuel J. Jayo , Elias A. Rivera , Thomas Spencer , Benjamin Watts
发明人: Timothy A. Bertram , Roger M. Ilagan , Russell W. Kelley , Sharon C. Presnell , Sumana Choudhury , Andrew T. Bruce , Christopher W. Genheimer , Bryan R. Cox , Kelly I. Guthrie , Joydeep Basu , Shay M. Wallace , Eric Werdin , Oluwatoyin A. Knight , Namrata D. Sangha , John W. Ludlow , Craig R. Halberstadt , Richard Payne , Neil F. Robins , Darell McCoy , Deepak Jain , Manuel J. Jayo , Elias A. Rivera , Thomas Spencer , Benjamin Watts
IPC分类号: C12N15/113 , C12N5/071 , C12Q1/6883
摘要: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
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