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公开(公告)号：US12096986B2
公开(公告)日：2024-09-24
申请号：US17314338
申请日：2021-05-07
Inventor： Ioannis S. Chatzizisis
CPC classification number: A61B34/10 , A61B90/37 , G06T17/20 , A61B2034/102 , A61B2034/105 , A61B2090/3762 , A61B2090/378 , G06T2210/41
Abstract: In accordance with embodiments of this disclosure, a computational simulation platform comprises a computer-implemented method that includes: generating a mesh or meshless three-dimensional (3D) reconstruction of a vessel lumen and a surface of the vessel lumen based on invasive or non-invasive imaging; assigning material properties to the 3D reconstructed surface of the vessel lumen based on the invasive or non-invasive imaging; performing balloon pre-dilation, stenting and balloon post-dilation computational simulations with the 3D reconstructed vessel lumen and surface of the vessel lumen; and assessing stent and vessel morphometric and biomechanical measures based on the computational simulations.
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公开(公告)号：US11419317B2
公开(公告)日：2022-08-23
申请号：US16615578
申请日：2019-03-18
Applicant: Central Institute for Experimental Animals , the Board of Regents of the University of Nebraska
Inventor： Larisa Poluektova , Santhi Gorantla , Mamoru Ito , Ikumi Katano
IPC: A01K67/027 , C12N5/079
Abstract: The present invention provides a non-human animal having human interleukin-34 (IL-34) in the body thereof; a method for producing a non-human animal having human microglia, which includes transplanting human CD34-positive hematopoietic stem cells into the non-human animal having human IL-34 in the body; and a method for producing human microglia, which includes obtaining human microglia from the non-human animal having human microglia.
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公开(公告)号：US20210130206A1
公开(公告)日：2021-05-06
申请号：US17089472
申请日：2020-11-04
Inventor： Paul N. Black , James W. Allen , Timothy J. Nicodemus
IPC: C02F3/32
Abstract: A method and system for reducing the concentration of nitrogen-bound nitrate from at least one of groundwater, surface water, or waste water is disclosed. The system includes an algal photobioreactor system. The photobioreactor includes a transparent tubular structure, a medium disposed inside the transparent tubular structure, and alga configured to adhere to the medium. The photobioreactor further includes a pump, and a light source. The method includes providing contaminant-containing water, adding the water to the algal photobioreactor system, adjusting at least one of temperature, ion concentration, CO2 concentration, pH, light wavelength, ion concentration or light intensity in the algal photobioreactor system to enhance growth of algae, removing water from the algal photobioreactor system, and harvesting the algal biomass. A system and method are also disclosed for reducing the concentration of organophosphates from water via an organophosphate-removing alga.
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公开(公告)号：US20180305713A1
公开(公告)日：2018-10-25
申请号：US16027066
申请日：2018-07-03
Inventor： Blair D. Siegfried , Kenneth E. Narva , Kanika Arora , Sarah E. Worden , Chitvan Khajuria , Elane Fishilevich , Nicholas P. Storer , Meghan Frey , Ronda L. Hamm , Ana Velez
IPC: C12N15/82 , A01N57/16 , A01N63/02 , C12N15/113
CPC classification number: C12N15/8286 , A01N57/16 , A01N63/02 , C07K2319/21 , C12N15/113 , C12N15/8218 , C12N2310/14 , Y02A40/162
Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of hemipteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in hemipteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of hemipteran pests, and the plant cells and plants obtained thereby.
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公开(公告)号：US20180305694A1
公开(公告)日：2018-10-25
申请号：US16027106
申请日：2018-07-03
Inventor： Blair D. Siegfried , Kenneth E. Narva , Kanika Arora , Sarah E. Worden , Chitvan Khajuria , Elane Fishilevich , Nicholas P. Storer , Meghan Frey , Ronda L. Hamm , Ana Velez
IPC: C12N15/113 , C12N15/82 , A01N37/46 , A01N57/16
CPC classification number: C12N15/113 , A01N37/46 , A01N57/16 , C12N15/8218 , C12N15/8286 , C12N2310/14 , Y02A40/162
Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of hemipteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in hemipteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of hemipteran pests, and the plant cells and plants obtained thereby.
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Patent Agency Ranking
公开(公告)号：US10047374B2
公开(公告)日：2018-08-14
申请号：US14971550
申请日：2015-12-16
Inventor： Blair D. Siegfried , Kenneth E. Narva , Kanika Arora , Sarah E. Worden , Chitvan Khajuria , Elane Fishilevich , Nicholas P. Storer , Meghan Frey , Ronda L. Hamm , Ana Velez
IPC: C12N15/82 , C12N15/113 , A01N57/16
Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of hemipteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in hemipteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of hemipteran pests, and the plant cells and plants obtained thereby.
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公开(公告)号：US20170304308A1
公开(公告)日：2017-10-26
申请号：US15517581
申请日：2015-10-09
Inventor： Howard E. Gendelman , Xin-Ming Liu , Benson Edagwa
CPC classification number: A61K31/52 , A61K9/0019 , A61K9/5146 , A61K31/513 , A61K47/542 , A61K47/551 , A61K47/64 , A61K47/6901 , A61K47/6907 , A61K47/6921 , A61K47/6929 , C07D411/04 , C07D473/16
Abstract: The present invention provides compositions and methods for the delivery of antivirals to a cell or subject.
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公开(公告)号：US20170296703A1
公开(公告)日：2017-10-19
申请号：US15510338
申请日：2015-09-29
Inventor： Jingwei Xie , Jiang Jiang
CPC classification number: A61L27/56 , A61K9/0092 , A61K9/70 , A61L27/18 , A61L27/38 , A61L2400/12 , D01D5/003 , D01D10/00 , D10B2331/041 , D10B2401/10
Abstract: Three dimensional nanofiber structures are provided and methods of production thereof.
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公开(公告)号：US20170218463A1
公开(公告)日：2017-08-03
申请号：US15422409
申请日：2017-02-01
Inventor： Sally A. Mackenzie , Robersy Sanchez
CPC classification number: C12Q1/6895 , C12Q2600/13 , C12Q2600/154 , G16B20/00 , G16B20/20 , G16B30/00 , G16B40/00 , G16H50/20 , Y02A90/26
Abstract: A computer-implemented method of preparing a set of differentially informative methylated positions (DIMPs) or differentially informative methylated regions (DIMRs) from a sample methylome of an animal or plant having a phenotypic characteristic different from a wild-type of the same species of animal or plant, and the characteristic is associate with differences in methylation of the genome, comprises: providing a computer with the sample methylome, and a reference methylome of the wild-type of the same species of animal or plant; calculating with the computer a divergence between a plurality of cytosine positions of the sample methylome and the reference methylome; and selecting with the computer a set of DIMPs or DIMRs. Each DIMP or DIMR is selected based on an approximation of the energy required to produce the divergence between methylation levels of the plurality of cytosine positions of the sample methylome as compared to the wild-type methylome.
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10.发明授权Methods of estimating a position of a rotor in a motor under transient and systems thereof 有权在瞬态及其系统下估计电机中转子的位置的方法公开(公告)号：US09577555B2
公开(公告)日：2017-02-21
申请号：US14243252
申请日：2014-04-02
CPC classification number: H02P6/183 , H02P6/18 , H02P21/0007 , H02P21/18 , H02P23/12
Abstract: At least one example embodiment discloses a method of estimating a position of a rotor in a motor. The method includes obtaining a current regulation quality index based on a current command and a measured current, determining an estimated position of the rotor based on the current regulation quality index and position estimation data and controlling the motor based on the estimated position of the rotor.
Abstract translation: 至少一个示例性实施例公开了一种估计电动机中的转子的位置的方法。 该方法包括基于电流指令和测量电流获得电流调节质量指标，基于当前调节质量指标和位置估计数据确定转子的估计位置，并基于转子的估计位置来控制电动机。
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