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公开(公告)号：US20130084220A1
公开(公告)日：2013-04-04
申请号：US13252195
申请日：2011-10-03
申请人： MING-HSIN LI , JIN-JENN LIN , THER-JEN TING , I-LEA DAI
发明人： MING-HSIN LI , JIN-JENN LIN , THER-JEN TING , I-LEA DAI
IPC分类号： B01J19/00
CPC分类号： G21G4/08 , A61K51/02 , G21G1/0005 , G21G2001/0021 , Y10S422/903
摘要： The invention is related a novel structure for Ga-68 radionuclide generator. It allows two washing solutions to pass through two Ge-68 absorbents to wash out different chemical forms of Ga-68 nuclide. The invention comprises the first method that will withdraw hydrochloric acid solution from the washing bottle and pass it through inorganic resin absorbing column to produce the radioisotope solution of Ga-68 gallium chloride, and the second method that will allow the radioisotope solution of Ga-68 gallium citrate to pass the organic resin absorbing column and then the silica-gel cartridge, and be washed by the hydrochloric acid solution to obtain the radioisotope solution of Ga-68 gallium chloride.
摘要翻译： 本发明涉及Ga-68放射性核素发生器的新型结构。 它允许两种洗涤溶液通过两种Ge-68吸收剂以洗出不同化学形式的Ga-68核素。 本发明包括第一种从洗瓶中取出盐酸溶液并将其通过无机树脂吸收塔以产生Ga-68氯化镓的放射性同位素溶液的方法，第二种方法将允许Ga-68的放射性同位素溶液 柠檬酸镓通过有机树脂吸收柱，然后通过硅胶柱，用盐酸溶液洗涤，得到Ga-68氯化镓的放射性同位素溶液。
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公开(公告)号：US08802014B2
公开(公告)日：2014-08-12
申请号：US13252195
申请日：2011-10-03
申请人： Ming-Hsin Li , Jin-Jenn Lin , Ther-Jen Ting , I-Lea Dai
发明人： Ming-Hsin Li , Jin-Jenn Lin , Ther-Jen Ting , I-Lea Dai
CPC分类号： G21G4/08 , A61K51/02 , G21G1/0005 , G21G2001/0021 , Y10S422/903
摘要： The invention is related a novel structure for Ga-68 radionuclide generator. It allows two washing solutions to pass through two Ge-68 absorbents to wash out different chemical forms of Ga-68 nuclide. The invention comprises the first method that will withdraw hydrochloric acid solution from the washing bottle and pass it through inorganic resin absorbing column to produce the radioisotope solution of Ga-68 gallium chloride, and the second method that will allow the radioisotope solution of Ga-68 gallium citrate to pass the organic resin absorbing column and then the silica-gel cartridge, and be washed by the hydrochloric acid solution to obtain the radioisotope solution of Ga-68 gallium chloride.
摘要翻译： 本发明涉及Ga-68放射性核素发生器的新型结构。 它允许两种洗涤溶液通过两种Ge-68吸收剂以洗出不同化学形式的Ga-68核素。 本发明包括第一种从洗瓶中取出盐酸溶液并将其通过无机树脂吸收塔以产生Ga-68氯化镓的放射性同位素溶液的方法，第二种方法将允许Ga-68的放射性同位素溶液 柠檬酸镓通过有机树脂吸收柱，然后通过硅胶柱，用盐酸溶液洗涤，得到Ga-68氯化镓的放射性同位素溶液。
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公开(公告)号：US08894860B2
公开(公告)日：2014-11-25
申请号：US12963263
申请日：2010-12-08
申请人： Ming-Hsin Li , Jin-Jenn Lin , Ther-Jen Ting , I-Lea Dai
发明人： Ming-Hsin Li , Jin-Jenn Lin , Ther-Jen Ting , I-Lea Dai
CPC分类号： B01D15/361 , G21G1/0005 , G21G2001/0021
摘要： A Gallium-68 (Ga-68) radioisotope generator includes a generating column and a citrate eluent. The generating column is at least partially filled with an ion-exchange resin with glucamine groups to absorb germanium-68 (Ge-68) and Ga-68 radioisotopes. The citrate eluent is added into the generating column to desorb the Ga-68 radioisotope and form an eluent containing the Ga-68 radioisotope in the form of Ga-68 citrate. A method for generating Ga-68 radioisotope is also disclosed.
摘要翻译： 镓68（Ga-68）放射性同位素发生器包括产生柱和柠檬酸盐洗脱液。 生成塔至少部分地填充有具有葡糖胺基团的离子交换树脂以吸收锗-68（Ge-68）和Ga-68放射性同位素。 将柠檬酸盐洗脱液加入产生塔中以解吸Ga-68放射性同位素，形成含有Ga-68柠檬酸盐形式的Ga-68放射性同位素的洗脱液。 还公开了一种生成Ga-68放射性同位素的方法。
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公开(公告)号：US20120011965A1
公开(公告)日：2012-01-19
申请号：US12963263
申请日：2010-12-08
申请人： Ming-Hsin LI , Jin-Jenn Lin , Ther-Jen Ting , I-Lea Dai
发明人： Ming-Hsin LI , Jin-Jenn Lin , Ther-Jen Ting , I-Lea Dai
CPC分类号： B01D15/361 , G21G1/0005 , G21G2001/0021
摘要： A Gallium-68 (Ga-68) radioisotope generator includes a generating column and a citrate eluent. The generating column is at least partially filled with an ion-exchange resin with glucamine groups to absorb germanium-68 (Ge-68) and Ga-68 radioisotopes. The citrate eluent is added into the generating column to desorb the Ga-68 radioisotope and form an eluent containing the Ga-68 radioisotope in the form of Ga-68 citrate. A method for generating Ga-68 radioisotope is also disclosed.
摘要翻译： 镓68（Ga-68）放射性同位素发生器包括产生柱和柠檬酸盐洗脱液。 生成塔至少部分地填充有具有葡糖胺基团的离子交换树脂以吸收锗-68（Ge-68）和Ga-68放射性同位素。 将柠檬酸盐洗脱液加入产生塔中以解吸Ga-68放射性同位素，形成含有Ga-68柠檬酸盐形式的Ga-68放射性同位素的洗脱液。 还公开了一种生成Ga-68放射性同位素的方法。
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