公开(公告)号：US20120186160A1

公开(公告)日：2012-07-26

申请号：US13389792

申请日：2010-08-10

申请人： Yoshiaki Morisada ,  Toru Nagaoka ,  Masao Fukusumi ,  Tadashi Mizuno ,  Genryu Abe ,  Hidetoshi Fujii

发明人： Yoshiaki Morisada ,  Toru Nagaoka ,  Masao Fukusumi ,  Tadashi Mizuno ,  Genryu Abe ,  Hidetoshi Fujii

IPC分类号： C09K3/14 ,  B24B1/00

CPC分类号： C23C4/18 ,  C23C4/06 ,  C23C26/00

摘要： Provided are a method of modifying a cemented carbide and a cemented carbide modified by the method. Particularly provided is an advantageous method of modifying a cemented carbide layer formed by a thermal spraying method on a surface of a metal substrate. The method of modifying a cemented carbide includes applying a friction stir process to a cemented carbide, thereby allowing crystal grains in a binder phase included in the cemented carbide to become finer. It is possible to achieve modification effectively by applying the friction stir process particularly to a cemented carbide layer formed on a surface of a metal substrate by using the thermal spraying method.

摘要翻译： 提供了通过该方法改性的硬质合金和硬质合金的改性方法。 特别提出的是在金属基板的表面上改变通过热喷涂法形成的硬质合金层的有利方法。 改性硬质合金的方法包括对硬质合金施加摩擦搅拌工艺，从而使包含在硬质合金中的粘结相中的晶粒变得更细。 通过使用热喷涂法将摩擦搅拌工艺特别地施加到形成在金属基材的表面上的硬质合金层可以有效地实现改性。

公开(公告)号：US07459573B2

公开(公告)日：2008-12-02

申请号：US11889524

申请日：2007-08-14

申请人： Tadashi Mizuno ,  Nobuhiro Arai ,  Erina Honda ,  Hideo Muraoka

发明人： Tadashi Mizuno ,  Nobuhiro Arai ,  Erina Honda ,  Hideo Muraoka

IPC分类号： C07D301/32

CPC分类号： C07D301/32 ,  C07D303/08

摘要： An epoxy compound of the formula (1): wherein, R represents a hydrogen atom or an alkyl group having 1 to 12 carbon atoms, and Ar represents an optionally substituted aromatic group, can be purified by dissolving a crude product containing the epoxy compound (1), an aprotic polar solvent and an alkali metal salt in a two-phase solvent composed of water and an organic solvent, which is capable of phase-separating from water, obtaining the organic layer by phase separation, washing with water and then subjecting to isolation of the epoxy compound (1) without decomposition.

公开(公告)号：US5498721A

公开(公告)日：1996-03-12

申请号：US271657

申请日：1994-07-07

申请人： Masahiko Mizuno ,  Isao Kurimoto ,  Norihiko Hirata ,  Toshiya Takahashi ,  Masayoshi Minai ,  Takahiro Yamamoto ,  Tadashi Mizuno ,  Yasunobu Miyamoto

发明人： Masahiko Mizuno ,  Isao Kurimoto ,  Norihiko Hirata ,  Toshiya Takahashi ,  Masayoshi Minai ,  Takahiro Yamamoto ,  Tadashi Mizuno ,  Yasunobu Miyamoto

IPC分类号： C07D495/04

CPC分类号： C07D495/04

摘要： A process for producing a thiophene derivative represented by a general formula (2) involves catalytically reducing a compound represnted by the general formula (1) with hydrogen in a solvent mixture of at least one of alcohol and water in the presence of a palladium catalyst soluble in organic solvents. A thiophene derivative is useful in preparing biotin (Vitamin H).

摘要翻译： 制备由通式（2）表示的噻吩衍生物的方法包括在钯催化剂可溶的存在下，在醇和水中的至少一种的溶剂混合物中用氢气还原由通式（1）表示的化合物 在有机溶剂中。 噻吩衍生物可用于制备生物素（维生素H）。

公开(公告)号：US5490192A

公开(公告)日：1996-02-06

申请号：US247854

申请日：1994-05-23

申请人： Junjiro Nakajima ,  Koji Nishida ,  Satoshi Kanno ,  Tadashi Mizuno ,  Yasunori Bessho ,  Masahisa Inagaki ,  Yasuhiro Aizawa

发明人： Junjiro Nakajima ,  Koji Nishida ,  Satoshi Kanno ,  Tadashi Mizuno ,  Yasunori Bessho ,  Masahisa Inagaki ,  Yasuhiro Aizawa

IPC分类号： G21C3/344 ,  G21C3/34

CPC分类号： G21C3/344 ,  G21Y2002/101 ,  G21Y2004/302 ,  Y02E30/40

摘要： A fuel assembly comprises a plurality of fuel rods, tie plates for holding both ends of these fuel rods, and spacers which support these fuel rods. The spacer comprises a plurality of cells into which the fuel rods are inserted respectively, the adjacent cells being joined to each other at axial ends thereof, whereby a space between these cells being held or retained, and a plurality of loop springs held respectively on the cells. Each of the loop springs has a pair of resilient members which are located within the pair of adjacent cells and which urge the fuel rods in a radial direction, and a pair of connections which connect axial ends of the resilient members to each other. Each of the connections have a passage through which coolant flows axially and which is defined by a closed peripheral wall. The closed peripheral wall is not uniform in thickness. The pair of adjacent cells have at axial end portions of peripheral walls openings for accommodating or receiving the connections of the loop spring.

摘要翻译： 燃料组件包括多个燃料棒，用于保持这些燃料棒的两端的连接板以及支撑这些燃料棒的间隔件。 间隔件包括分别插入燃料棒的多个单元，相邻的单元在其轴向端部彼此接合，由此保持或保持这些单元之间的空间，以及分别保持在该单元上的多个环形弹簧 细胞。 每个环形弹簧具有一对弹性构件，该弹性构件位于一对相邻的单元内并且沿径向推动燃料棒，以及将弹性构件的轴向端部彼此连接的一对连接件。 每个连接件都有一个通道，冷却剂通过该通道轴向流动，并由封闭的外围壁限定。 封闭的周边壁厚度不均匀。 一对相邻的单元具有用于容纳或接收环形弹簧的连接的外围壁开口的轴向端部。

公开(公告)号：US20130068735A1

公开(公告)日：2013-03-21

申请号：US13636951

申请日：2011-03-25

申请人： Yoshiaki Morisada ,  Masao Fukusumi ,  Toru Nagaoka ,  Tadashi Mizuno ,  Genryu Abe ,  Hidetoshi Fujii

发明人： Yoshiaki Morisada ,  Masao Fukusumi ,  Toru Nagaoka ,  Tadashi Mizuno ,  Genryu Abe ,  Hidetoshi Fujii

IPC分类号： C23C24/08 ,  B23K26/34 ,  B23K20/12

CPC分类号： C23C24/08 ,  B23K20/12 ,  B23K20/122 ,  B23K20/1275 ,  B23K20/128 ,  B23K26/14 ,  B23K26/144 ,  B23K26/1476 ,  B23K26/342 ,  B23K31/025 ,  B23K35/0244 ,  B23K35/327 ,  B23K2101/06 ,  B23K2101/20 ,  B23K2101/34 ,  C23C24/103 ,  Y10T428/31678

摘要： The present invention provides a method of forming a metal coating having a microstructure as well as a structural member having a metal coating formed by the method. In particular, the invention provides an advantageous method of forming a metal coating in which minute carbides are uniformly dispersed. The method of forming the metal coating of the present invention includes the steps of cladding a surface of the substrate with metal powder by a laser cladding method and forming the metal coating having a microstructure by applying a friction stir processing to the cladded region.

摘要翻译： 本发明提供一种形成具有微结构的金属涂层的方法以及具有通过该方法形成的金属涂层的结构件。 特别地，本发明提供了形成其中微小碳化物均匀分散的金属涂层的有利方法。 形成本发明的金属涂层的方法包括以下步骤：通过激光熔覆法用金属粉末包覆基板的表面，并通过对包覆区域进行摩擦搅拌处理来形成具有微结构的金属涂层。

公开(公告)号：US07569699B2

公开(公告)日：2009-08-04

申请号：US11791511

申请日：2005-11-29

申请人： Taro Ishibahsi ,  Hideo Muraoka ,  Tadashi Mizuno

发明人： Taro Ishibahsi ,  Hideo Muraoka ,  Tadashi Mizuno

IPC分类号： C07D249/02

CPC分类号： C07D405/06

摘要： This invention provides a process for producing an epoxytriazole derivative represented by formula (2): (wherein R and Ar are defined below), which comprises a step including a reaction of an epoxy derivative represented by formula (1′): (wherein R represents a hydrogen atom or C1-12 alkyl group and Ar represents an aromatic group optionally substituted by a halogen atom(s) or trifluoromethyl group(s), and X′ represents a hydroxy group or leaving group), with 1,2,4-triazole in the presence of a base and water.

摘要翻译： 本发明提供一种制备式（2）表示的环氧三唑衍生物的方法：其中R和Ar定义如下），其包括由式（1'）表示的环氧衍生物反应的步骤：其中R表示 氢原子或C 1-12烷基，Ar表示任选被卤素原子或三氟甲基取代的芳基，X'表示羟基或离去基团） 三唑在碱和水的存在下。

公开(公告)号：US20080081915A1

公开(公告)日：2008-04-03

申请号：US11791511

申请日：2005-11-29

申请人： Taro Ishibashi ,  Hideo Muraoka ,  Tadashi Mizuno

发明人： Taro Ishibashi ,  Hideo Muraoka ,  Tadashi Mizuno

IPC分类号： C07D249/08

CPC分类号： C07D405/06

摘要： This invention provides a process for producing an epoxytriazole derivative represented by formula (2): (wherein R and Ar are defined below), which comprises a step including a reaction of an epoxy derivative represented by formula (1′): (wherein R represents a hydrogen atom or C1-12 alkyl group and Ar represents an aromatic group optionally substituted by a halogen atom(s) or trifluoromethyl group(s), and X′ represents a hydroxy group or leaving group), with 1,2,4-triazole in the presence of a base and water.

摘要翻译： 本发明提供一种制备式（2）表示的环氧三唑衍生物的方法：其中R和Ar定义如下），其包括由式（1'）表示的环氧衍生物反应的步骤：其中R表示 氢原子或C 1-12烷基，Ar表示任选被卤素原子或三氟甲基取代的芳基，X'表示羟基或离去基团） 三唑在碱和水的存在下。

公开(公告)号：US20070238900A1

公开(公告)日：2007-10-11

申请号：US11571956

申请日：2005-07-13

申请人： Tadashi Katsura ,  Tadashi Mizuno ,  Nobushige Itaya

发明人： Tadashi Katsura ,  Tadashi Mizuno ,  Nobushige Itaya

IPC分类号： C07C261/04

CPC分类号： C07C315/06 ,  C07C317/46

摘要： The present invention provides a method of crystallization of bicalutamide comprising adding an acetone solution containing bicalutamide to water; crystals of bicalutamide wherein particle size distribution of the crystals is 1 to 10 μm of Dp10, 10 to 25 μm of Dp50 and 25 to 100 μm of Dp90, and the crystals are obtainable by the method described above; and crystals of bicalutamide, wherein particle size distribution of the crystals is 1 to 3 μm of Dp10, 2 to 5 μm of Dp50 and 5 to 15 μm of Dp90.

摘要翻译： 本发明提供了比卡鲁胺的结晶方法，包括将含有比卡鲁胺的丙酮溶液加入水中; 其中，结晶的粒径分布为Dp 10〜10μm，Dp <50> 10〜25μm，Dp <！ - SIPO 2〜5μm，Dp < SUB> 90 。

公开(公告)号：US07132548B2

公开(公告)日：2006-11-07

申请号：US11129357

申请日：2005-05-16

申请人： Tadashi Katsura ,  Nobuhiro Arai ,  Tadashi Mizuno

发明人： Tadashi Katsura ,  Nobuhiro Arai ,  Tadashi Mizuno

IPC分类号： C07D233/32

CPC分类号： C07D233/32

摘要： The present invention provides a process for recovering 1,3-dimethyl-2-imidazolidinone comprising extracting 1,3-dimethyl-2-imidazolidinone from an aqueous solution containing it with n-butanol in the presence of an inorganic salt to obtain n-butanol layer and, subjecting the n-butanol layer to distillation.As 1,3-dimethyl-2-imidazolidinone can be recoverable at high purity from an aqueous solution containing 1,3-dimethyl-2-imidazolidinone easily and efficiently without using alkali, the present process is industrially advantageous.

摘要翻译： 本发明提供一种回收1,3-二甲基-2-咪唑啉酮的方法，其包括在无机盐存在下，从含有正丁醇的水溶液中提取1,3-二甲基-2-咪唑啉酮，得到正丁醇 层，并使正丁醇层进行蒸馏。 由于1,3-二甲基-2-咪唑啉酮可以在不使用碱的情况下容易且有效地从含有1,3-二甲基-2-咪唑啉酮的水溶液中以高纯度回收，因此本工艺在工业上是有利的。

公开(公告)号：US5326916A

公开(公告)日：1994-07-05

申请号：US028534

申请日：1993-03-08

申请人： Yoshinori Kobayashi ,  Yasuo Matsumoto ,  Tadashi Mizuno ,  Masamitu Fukuda

发明人： Yoshinori Kobayashi ,  Yasuo Matsumoto ,  Tadashi Mizuno ,  Masamitu Fukuda

IPC分类号： C07B61/00 ,  B01J19/24 ,  C07C45/35 ,  C07C45/78 ,  C07C47/22 ,  C07C45/80

CPC分类号： C07C45/35 ,  B01J19/2465 ,  C07C45/783

摘要： A process for producing acrolein which comprises bringing a reaction gas resulting from a catalytic oxidation of propylene into contact in a cooling tower with a condensate which is being circulated through the cooling tower and a circulating part, thereby to cool and separate the reaction gas and discharge an effluent gas from the cooling tower, the condensate in a bottom part of the cooling tower having a temperature of from 35.degree. to 50.degree. C., the effluent gas discharged from the cooling tower having a temperature of from 35.degree. to 55.degree. C., the temperature of the effluent gas being kept nearly equal to or higher than the temperature of the condensate in the bottom part of the cooling tower, and a process for producing acrolein which comprises bringing a reaction gas resulting from the catalytic oxidation of propylene into contact in a cooling tower with a condensate which is being circulated through the cooling tower and a circulating part, thereby to cool and separate the reaction gases, the period of the residence time of the condensate in the cooling tower and the circulating part being from 0.5 to 3 hours.

摘要翻译： 一种制备丙烯醛的方法，其包括使由丙烯的催化氧化产生的反应气体在冷却塔中与冷却塔中循环的冷凝物和循环部分接触，从而冷却和分离反应气体并将其排出 来自冷却塔的废气，冷却塔底部的冷凝物的温度为35〜50℃，从冷却塔排出的流出气体的温度为35〜55℃ 流出气体的温度保持在冷却塔底部的冷凝水的温度近似等于或高于丙烯醛的制造方法，其特征在于，将由丙烯的催化氧化得到的反应气体 在冷却塔中与通过冷却塔循环的冷凝物和循环部分接触，从而冷却和分离反应物 冷凝塔和循环部分的冷凝水停留时间为0.5〜3小时。