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公开(公告)号：US08425405B2
公开(公告)日：2013-04-23
申请号：US12432053
申请日：2009-04-29
申请人： Takahiko Mitani , Akira Muramatsu , Seiji Sakai , Tomoaki Yamashita , Masahiro Kawauchi , Yuichi Wataya
发明人： Takahiko Mitani , Akira Muramatsu , Seiji Sakai , Tomoaki Yamashita , Masahiro Kawauchi , Yuichi Wataya
CPC分类号： A61B1/05 , A61B1/00114 , A61B1/018 , A61B1/042
摘要： An electronic endoscope apparatus includes: an image pickup apparatus mounted at a distal end portion of an insertion portion; an operation portion provided consecutively at the insertion portion, with a frame member incorporated therein; and an electrical cable extended from the operation portion for connection with an external device. In the electronic endoscope apparatus, the frame member has a circuit board portion which establishes electrical connection between shields of the insertion portion and the electrical cable, and on which various electronic parts for exchanging signals with the image pickup apparatus are mounted. In spite of the arrangement of the image pickup apparatus that can acquire high-quality images at a distal end portion of the insertion portion, a size of the apparatus, in particular, a diameter of the insertion portion, can be prevented from being increased.
摘要翻译： 电子内窥镜装置包括：安装在插入部的前端部的摄像装置; 连接在插入部分的操作部分，其中结合有框架构件; 以及从操作部分延伸的用于与外部设备连接的电缆。 在电子内窥镜装置中，框架构件具有在插入部的屏蔽和电缆之间建立电连接的电路基板部，并且安装有用于与图像拾取装置交换信号的各种电子部件。 尽管可以在插入部分的远端部分获得高质量图像的图像拾取装置的布置，但是可以防止装置的尺寸，特别是插入部分的直径增加。
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公开(公告)号：US20090185032A1
公开(公告)日：2009-07-23
申请号：US12333679
申请日：2008-12-12
申请人： Seiji SAKAI , Tomoaki YAMASHITA , Masahiro KAWAUCHI , Takahiko MITANI , Yuuya ISHIDA , Seiji IWASAKI
发明人： Seiji SAKAI , Tomoaki YAMASHITA , Masahiro KAWAUCHI , Takahiko MITANI , Yuuya ISHIDA , Seiji IWASAKI
CPC分类号： G02B23/2438 , A61B1/00096 , A61B1/00188 , A61B1/05 , F03G7/065
摘要： An image pickup apparatus of the present invention varies optical properties by moving a part of lenses of an objective lens, and includes a solid-state image pickup device unit that is disposed at a rear-end section and that subjects a subject image to photoelectric conversion, a fixed lens frame that retains the objective lens that is disposed in front of the solid-state image pickup device unit, a movable lens frame that retains the part of lenses that moves along a photographing optical axis O inside the lens frame, and an actuator having one end connected to the movable lens frame and that moves the movable lens frame forward and backward. The actuator includes a rigid member provided so as to extend to the vicinity of the rear end at which the solid-state image pickup device unit is disposed and a shape memory alloy that is coupled to the rigid member.
摘要翻译： 本发明的图像拾取装置通过移动物镜的一部分透镜来改变光学特性，并且包括设置在后端部分并使被摄体图像进行光电转换的固态图像拾取装置单元 ，固定透镜框架，其保持设置在固态摄像装置单元前面的物镜;可移动透镜框，其保持沿着拍摄光轴O在透镜框内移动的透镜部分;以及 致动器，其一端连接到可移动透镜框架并且使可移动透镜框架向前和向后移动。 致动器包括设置成延伸到固态图像拾取装置单元的后端附近的刚性构件和耦合到刚性构件的形状记忆合金。
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3.发明授权3-oxygermylpropionic acid polymer, pharmaceutical composition containing same and method of preventing and/or curing symptoms of immune diseases using same 失效3-氧基甲基丙酸聚合物，含有其的药物组合物，以及使用其来预防和/或治疗免疫疾病症状的方法
公开(公告)号：US5532272A
公开(公告)日：1996-07-02
申请号：US246141
申请日：1994-05-20
CPC分类号： C07F7/30
摘要： A novel, eight structural polymer of 2-oxygermylpropionic acid having an empirical formula of C.sub.6 H.sub.10 Ge.sub.2 O.sub.7, a minimum constitutional unit of (O.sub.1/2).sub.3 GeCH.sub.2 CH.sub.2 COOH and the following stereostructure: ##STR1## wherein R stands for --CH.sub.2 CH.sub.2 COOH and m is an integer of 137.+-.84. A pharmaceutical composition containing the novel polymer is useful for preventing symptoms of an immune disease such as hepatitis or for curing such a disease.
摘要翻译： 具有经验式为C 6 H 10 Ge 2 O 7的2-羟基甲基丙酸的新型八元结构聚合物，（O1 / 2）3GeCH2CH2COOH的最小结构单元和以下立体结构：其中R代表-CH2CH2COOH，m是137的整数 +/- 84。 含有新型聚合物的药物组合物可用于预防免疫疾病例如肝炎或治愈这种疾病的症状。
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公开(公告)号：US5432261A
公开(公告)日：1995-07-11
申请号：US943992
申请日：1992-09-11
申请人： Masayasu Kurono , Takahiko Mitani , Haruo Takahashi , Kenichi Tanaka , Katsuya Fujimura , Yuji Hayashi , Yohei Kobayashi , Kiichi Sawai
发明人： Masayasu Kurono , Takahiko Mitani , Haruo Takahashi , Kenichi Tanaka , Katsuya Fujimura , Yuji Hayashi , Yohei Kobayashi , Kiichi Sawai
CPC分类号： C07K14/63 , A61K38/00 , C07K2319/02
摘要： A pharmaceutical composition for stimulating peristaltic contraction in the intestinal canal which contains a pharmaceutically acceptable carrier or excipient and an effective amount of a polypeptide, or a salt thereof, having a pharmacological activity similar to motilin. The polypeptide has the formula B.sub.1 -Z.sub.1 -A.sub.1 -Z.sub.2 -B.sub.2 -Thr-B.sub.3 -A.sub.2 -Glu-Z.sub.3 -C-Arg-X'-Gln-Glu-Lys-Glu-Arg-D-Lys-Gly-E-Y, with Z.sub.1,Z.sub.2 and Z.sub.3 each being an amino acid residue having a hydrophobic side-chain, A.sub.1 and A.sub.2 each being an amino acid residue such as Pro, Gly, Asn and Ser, B.sub.1, B.sub.2 and B.sub.3 are each an amino acid residue having a side-chain with an aromatic ring, C is Gln, Glu or Asp, D is Asn, Glu or Asp, X' is an amino acid residue other than Met, E is Gln, Lys or Arg, and Y is homoserine, homoserine-lactone or a peptide chain having amino acid residues not exceeding 10 and containing homoserine or homoserine-lactone at the C-terminal where the first amino acid of said peptide chain is other than Lys, Arg or Pro.
摘要翻译： 一种用于刺激肠道蠕动收缩的药物组合物，其含有药学上可接受的载体或赋形剂和有效量的具有与胃动素相似的药理活性的多肽或其盐。 该多肽具有式B1-Z1-A1-Z2-B2-Thr-B3-A2-Glu-Z3-C-Arg-X'-Gln-Glu-Lys-Glu-Arg-D-Lys-Gly-EY， Z 1，Z 2和Z 3各自为具有疏水侧链的氨基酸残基，A1和A2各自为氨基酸残基，例如Pro，Gly，Asn和Ser，B1，B2和B3各自为具有 具有芳环的侧链，C是Gln，Glu或Asp，D是Asn，Glu或Asp，X'是Met以外的氨基酸残基，E是Gln，Lys或Arg，Y是高丝氨酸，高丝氨酸 β-内酯或氨基酸残基不超过10的肽链，并且在所述肽链的第一个氨基酸不是Lys，Arg或Pro的C末端含有高丝氨酸或高丝氨酸 - 内酯。
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公开(公告)号：US5428015A
公开(公告)日：1995-06-27
申请号：US201092
申请日：1994-02-24
IPC分类号： A61K38/00 , C07K14/575 , C07K7/08
CPC分类号： C07K14/57563 , A61K38/00
摘要： Vasoactive intestinal polypeptide (VIP) analogues and use thereof are disclosed. The VIP analogues are shown by the formula ofHis-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-X-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-Ywherein X is a residue of amino acid other than methionine (Met); and Y is homoserine, homoserine-lactone, amidized homoserine, a residue reacted homoserine-lactone with a primary alkyl amine having carbon atoms not exceeding 20, or an optional polypeptide chain and containing an amidized homoserine at C-terminal.Each of the VIP analogues is employed as an effective ingredient for various medicines and a hair tonic, and more particularly curing an asthma and impotence.
摘要翻译： 公开了血管活性肠肽（VIP）类似物及其用途。 VIP类似物以His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-X-Ala-Val-Lys-Lys -Tyr-Leu-Asn-Ser-Ile-Leu-Asn-Y其中X是甲硫氨酸以外的氨基酸残基（Met）; 并且Y是高丝氨酸，高丝氨酸 - 内酯，酰胺化高丝氨酸，残基与高丝氨酸 - 内酯与碳原子数不超过20的伯烷基胺反应，或任选的多肽链，并且在C-末端含有酰胺化的高丝氨酸。 每种VIP类似物被用作各种药物和头发补品的有效成分，更特别地治疗哮喘和阳。。
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公开(公告)号：US5211956A
公开(公告)日：1993-05-18
申请号：US346852
申请日：1989-05-03
IPC分类号： A61K31/66
CPC分类号： A61K31/66
摘要： Pharmaceutical compositions for oral administration used for the treatment and prevention of hyperlipemia, obesity and obesity-related diseases contain phytic acid or its salt as a pharmaceutically effective component.
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公开(公告)号：US4929438A
公开(公告)日：1990-05-29
申请号：US310162
申请日：1989-02-15
申请人： Kiichi Sawai , Masayasu Kurono , Hiromiotu Asai , Takahiko Mitani , Naohisa Ninomiya , Takao Sugiyama , Eiji Furukawa , Hisashi Michishita
发明人： Kiichi Sawai , Masayasu Kurono , Hiromiotu Asai , Takahiko Mitani , Naohisa Ninomiya , Takao Sugiyama , Eiji Furukawa , Hisashi Michishita
IPC分类号： A61K31/66 , A61K36/00 , A61K36/899 , A61P25/30
CPC分类号： A61K31/66 , Y10S514/811
摘要： Preventives or remedies for medicinal and alcoholic poisoning contain as a pharmaceutically effective component phytic acid or its salt which may be an innoxious metal salt, or an innoxious salt with an organic base, a basic amino acid or an organic ester residue.
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公开(公告)号：US09007449B2
公开(公告)日：2015-04-14
申请号：US11649974
申请日：2007-01-05
申请人： Takahiko Mitani , Kazuhiro Kumei , Kazuyoshi Akiba , Seiji Sakai , Hironobu Ichimura , Masahiro Kawauchi
发明人： Takahiko Mitani , Kazuhiro Kumei , Kazuyoshi Akiba , Seiji Sakai , Hironobu Ichimura , Masahiro Kawauchi
CPC分类号： A61B1/05 , A61B1/00096 , A61B1/00098 , A61B1/00101 , A61B1/018 , A61B1/051 , A61B1/053
摘要： An image-capturing apparatus and a repair method thereof are provided. The image-capturing apparatus includes a lens frame to which one or more lenses are fixed; an image-capturing frame to which an image-capturing device is fixed; and a fixing member for fixing the lens frame and the image-capturing frame to each other without adhering a fitted portion between the lens frame and the image-capturing frame. The repair method for the image-capturing apparatus includes destructing a fixing member for fixing to each other a lens frame to which one or more lenses are fixed and an image-capturing frame to which an image-capturing device is fixed, and releasing fixing between the frames; replacing at least either of the lens frame and the image-capturing frame; and fixing to each other the lens frame and the image-capturing frame.
摘要翻译： 提供了一种图像捕获装置及其修复方法。 图像拍摄装置包括固定有一个或多个透镜的透镜框; 图像捕获装置固定在其上的图像捕获帧; 以及固定构件，用于将透镜框和图像捕获框架彼此固定，而不将粘合部分粘附在透镜框架和图像捕获框架之间。 图像拍摄装置的修复方法包括破坏用于固定一个或多个透镜固定的透镜框的固定构件和固定有图像捕获装置的图像捕获框架，并且释放固定在 框架; 替代透镜框和图像捕获框架中的至少一个; 并且将透镜框和图像捕获框架彼此固定。
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公开(公告)号：US08427533B2
公开(公告)日：2013-04-23
申请号：US12333679
申请日：2008-12-12
申请人： Seiji Sakai , Tomoaki Yamashita , Masahiro Kawauchi , Takahiko Mitani , Yuuya Ishida , Seiji Iwasaki
发明人： Seiji Sakai , Tomoaki Yamashita , Masahiro Kawauchi , Takahiko Mitani , Yuuya Ishida , Seiji Iwasaki
IPC分类号： H04N7/18
CPC分类号： G02B23/2438 , A61B1/00096 , A61B1/00188 , A61B1/05 , F03G7/065
摘要： An image pickup apparatus of the present invention varies optical properties by moving a part of lenses of an objective lens, and includes a solid-state image pickup device unit that is disposed at a rear-end section and that subjects a subject image to photoelectric conversion, a fixed lens frame that retains the objective lens that is disposed in front of the solid-state image pickup device unit, a movable lens frame that retains the part of lenses that moves along a photographing optical axis O inside the lens frame, and an actuator having one end connected to the movable lens frame and that moves the movable lens frame forward and backward. The actuator includes a rigid member provided so as to extend to the vicinity of the rear end at which the solid-state image pickup device unit is disposed and a shape memory alloy that is coupled to the rigid member.
摘要翻译： 本发明的图像拾取装置通过移动物镜的一部分透镜来改变光学特性，并且包括设置在后端部分并使被摄体图像进行光电转换的固态图像拾取装置单元 ，固定透镜框架，其保持设置在固态摄像装置单元前面的物镜;可移动透镜框，其保持沿着拍摄光轴O在透镜框内移动的透镜部分;以及 致动器，其一端连接到可移动透镜框架并且使可移动透镜框架向前和向后移动。 致动器包括设置成延伸到固态图像拾取装置单元的后端附近的刚性构件和耦合到刚性构件的形状记忆合金。
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公开(公告)号：US06579560B2
公开(公告)日：2003-06-17
申请号：US09802459
申请日：2001-03-09
IPC分类号： A23L120
摘要： A soybean processed food having crisp feelings of eating and good tasting is provided. The soybean processed food is produced by kneading a mixture of a soybean-derived material and a condiment in the presence of water to obtain dough, and drying the dough under a reduced pressure of 0.1 kPa to 10 kPa. It is preferred that the soybean-derived material contains isolated soybean protein as the major constituent, soybean saccharide, soybean dietary fiber, and/or soybean lecithin. According to this soybean processed food, users of all ages can easily and efficiently ingest nutrients of soybean
摘要翻译： 提供了一种大豆加工食品，具有清脆的食欲和品尝感。 大豆加工食品通过在水存在下捏合大豆来源的材料和调味品的混合物来制得面团，并在0.1kPa至10kPa的减压下干燥面团。 优选大豆来源的材料含有分离的大豆蛋白作为主要成分，大豆糖，大豆膳食纤维和/或大豆卵磷脂。 根据这种大豆加工食品，所有年龄段的用户可以容易地和有效地摄取大豆的营养
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