公开(公告)号：US20100229249A1

公开(公告)日：2010-09-09

申请号：US12600223

申请日：2009-02-20

申请人： Tetsuro Miki ,  Yasuharu Tabara ,  Katsuhiko Kohara ,  Jun Nakura ,  Satoshi Umemura ,  Nobuhito Hirawa ,  Hirotsugu Ueshima ,  Yoshikuni Kita ,  Yasuyuki Nakamura

发明人： Tetsuro Miki ,  Yasuharu Tabara ,  Katsuhiko Kohara ,  Jun Nakura ,  Satoshi Umemura ,  Nobuhito Hirawa ,  Hirotsugu Ueshima ,  Yoshikuni Kita ,  Yasuyuki Nakamura

IPC分类号： A01K67/00 ,  C07H21/04 ,  C12Q1/68 ,  C40B40/06 ,  C12N15/63

CPC分类号： C12N15/8509 ,  C12N2800/30 ,  C12Q1/6883 ,  C12Q2600/156

摘要： Provided in the present invention is a genetic marker including a SNP which can be used for assessing the risk of developing hypertension, a polynucleotide for assessing the risk of developing hypertension which can be used as a primer or probe for detecting the genetic marker, a method for assessing the risk of developing hypertension using the SNP, a microarray for assessing the risk of developing hypertension which is used for genotyping of the SNP, a kit used in the method for assessing the risk of developing hypertension, and the like.

摘要翻译： 本发明提供了包括可用于评估发生高血压风险的SNP的遗传标记，用于评估可用作检测遗传标记的引物或探针的发生高血压的风险的多核苷酸，方法 用于评估使用SNP发生高血压的风险，用于评估用于SNP基因分型的高血压发生风险的微阵列，用于评估发生高血压风险的方法的试剂盒等。

公开(公告)号：US20100138943A1

公开(公告)日：2010-06-03

申请号：US12621235

申请日：2009-11-18

申请人： Tetsuro Miki ,  Yasuharu Tabara ,  Katsuhiko Kohara ,  Jun Nakura ,  Satoshi Umemura ,  Nobuhito Hirawa ,  Hirotsugu Ueshima ,  Yoshikuni Kita ,  Yasuyuki Nakamura

发明人： Tetsuro Miki ,  Yasuharu Tabara ,  Katsuhiko Kohara ,  Jun Nakura ,  Satoshi Umemura ,  Nobuhito Hirawa ,  Hirotsugu Ueshima ,  Yoshikuni Kita ,  Yasuyuki Nakamura

IPC分类号： A01K67/00 ,  C07H21/04 ,  C12Q1/68 ,  C40B40/08 ,  C12N15/63

CPC分类号： A01K67/0276 ,  A01K2217/075 ,  A01K2217/206 ,  A01K2227/105 ,  A01K2267/0375 ,  C12N9/14 ,  C12N15/8509 ,  C12N2800/30 ,  C12Q1/6883 ,  C12Q2600/156

摘要： A genetic marker including a SNP which can be used for assessing the risk of developing hypertension, a polynucleotide for assessing the risk of developing hypertension which can be used as a primer or probe for detecting the genetic marker, a method for assessing the risk of developing hypertension using the SNP, a microarray for assessing the risk of developing hypertension which is used for genotyping of the SNP, a kit used in the method for assessing the risk of developing hypertension, and the like.

摘要翻译： 包括可用于评估发生高血压风险的SNP的遗传标记，用于评估可用作检测遗传标记的引物或探针的发展中的高血压风险的多核苷酸，评估发展风险的方法 使用SNP的高血压，用于评估用于SNP基因分型的高血压发生风险的微阵列，用于评估发生高血压的风险的方法的试剂盒等。

公开(公告)号：US4611049A

公开(公告)日：1986-09-09

申请号：US727088

申请日：1985-04-25

申请人： Taketoshi Kuratsuji ,  Tetsuro Miki

发明人： Taketoshi Kuratsuji ,  Tetsuro Miki

IPC分类号： C08G63/82 ,  C08G63/34

CPC分类号： C08G63/82

摘要： A process for producing an aromatic polyester having an aromatic dicarboxylic acid as a main acid component and trimethylene glycol or tetramethylene glycol as a main glycol component from a starting material composed mainly of an aromatic dicarboxylic acid or its functional derivative and trimethylene glycol or tetramethylene glycol; wherein at least one organometallic catalyst selected from the group consisting of organotitanium compounds and organotin compounds and at least one promoter selected from the group consisting of organic sulfonic acids and aliphatic carboxylic acids and being capable of increasing the catalyst activity of the organometallic catalyst are added to the reaction system so that the promoter increases the catalytic activity of the organometallic catalyst, and an aromatic polyester having an increased degree of polymerization is formed at an increased rate of polymerization.

摘要翻译： 由主要由芳族二羧酸或其功能性衍生物和三亚甲基二醇或四亚甲基二醇组成的起始原料制备具有芳族二羧酸作为主要酸成分和三亚甲基二醇或四亚甲基二醇作为主要二醇成分的芳族聚酯的方法， 其中至少一种选自有机钛化合物和有机锡化合物的有机金属催化剂和至少一种选自有机磺酸和脂族羧酸并且能够增加有机金属催化剂的催化剂活性的助催化剂加入到 该反应体系使助催化剂增加了有机金属催化剂的催化活性，并以增加的聚合速率形成聚合度增加的芳族聚酯。