公开(公告)号：US20100138943A1

公开(公告)日：2010-06-03

申请号：US12621235

申请日：2009-11-18

申请人： Tetsuro Miki ,  Yasuharu Tabara ,  Katsuhiko Kohara ,  Jun Nakura ,  Satoshi Umemura ,  Nobuhito Hirawa ,  Hirotsugu Ueshima ,  Yoshikuni Kita ,  Yasuyuki Nakamura

发明人： Tetsuro Miki ,  Yasuharu Tabara ,  Katsuhiko Kohara ,  Jun Nakura ,  Satoshi Umemura ,  Nobuhito Hirawa ,  Hirotsugu Ueshima ,  Yoshikuni Kita ,  Yasuyuki Nakamura

IPC分类号： A01K67/00 ,  C07H21/04 ,  C12Q1/68 ,  C40B40/08 ,  C12N15/63

CPC分类号： A01K67/0276 ,  A01K2217/075 ,  A01K2217/206 ,  A01K2227/105 ,  A01K2267/0375 ,  C12N9/14 ,  C12N15/8509 ,  C12N2800/30 ,  C12Q1/6883 ,  C12Q2600/156

摘要： A genetic marker including a SNP which can be used for assessing the risk of developing hypertension, a polynucleotide for assessing the risk of developing hypertension which can be used as a primer or probe for detecting the genetic marker, a method for assessing the risk of developing hypertension using the SNP, a microarray for assessing the risk of developing hypertension which is used for genotyping of the SNP, a kit used in the method for assessing the risk of developing hypertension, and the like.

摘要翻译： 包括可用于评估发生高血压风险的SNP的遗传标记，用于评估可用作检测遗传标记的引物或探针的发展中的高血压风险的多核苷酸，评估发展风险的方法 使用SNP的高血压，用于评估用于SNP基因分型的高血压发生风险的微阵列，用于评估发生高血压的风险的方法的试剂盒等。

公开(公告)号：US20100229249A1

公开(公告)日：2010-09-09

申请号：US12600223

申请日：2009-02-20

申请人： Tetsuro Miki ,  Yasuharu Tabara ,  Katsuhiko Kohara ,  Jun Nakura ,  Satoshi Umemura ,  Nobuhito Hirawa ,  Hirotsugu Ueshima ,  Yoshikuni Kita ,  Yasuyuki Nakamura

发明人： Tetsuro Miki ,  Yasuharu Tabara ,  Katsuhiko Kohara ,  Jun Nakura ,  Satoshi Umemura ,  Nobuhito Hirawa ,  Hirotsugu Ueshima ,  Yoshikuni Kita ,  Yasuyuki Nakamura

IPC分类号： A01K67/00 ,  C07H21/04 ,  C12Q1/68 ,  C40B40/06 ,  C12N15/63

CPC分类号： C12N15/8509 ,  C12N2800/30 ,  C12Q1/6883 ,  C12Q2600/156

摘要： Provided in the present invention is a genetic marker including a SNP which can be used for assessing the risk of developing hypertension, a polynucleotide for assessing the risk of developing hypertension which can be used as a primer or probe for detecting the genetic marker, a method for assessing the risk of developing hypertension using the SNP, a microarray for assessing the risk of developing hypertension which is used for genotyping of the SNP, a kit used in the method for assessing the risk of developing hypertension, and the like.

摘要翻译： 本发明提供了包括可用于评估发生高血压风险的SNP的遗传标记，用于评估可用作检测遗传标记的引物或探针的发生高血压的风险的多核苷酸，方法 用于评估使用SNP发生高血压的风险，用于评估用于SNP基因分型的高血压发生风险的微阵列，用于评估发生高血压风险的方法的试剂盒等。

公开(公告)号：US20090070046A1

公开(公告)日：2009-03-12

申请号：US12298186

申请日：2007-04-24

申请人： Noriko Kenjou ,  Yuko Taniike ,  Tatsurou Kawamura ,  Noriko Shimba ,  Hirotsugu Ueshima ,  Tomonori Okamura ,  Atsushi Hozawa

发明人： Noriko Kenjou ,  Yuko Taniike ,  Tatsurou Kawamura ,  Noriko Shimba ,  Hirotsugu Ueshima ,  Tomonori Okamura ,  Atsushi Hozawa

IPC分类号： G01N33/50

CPC分类号： G01N33/493

摘要： A daily urinary excretion measurement apparatus and a method thereof, for measuring daily excretion of a urine component highly accurately and easily, are provided.A daily urinary excretion measurement apparatus (100) includes: a urine component calculation unit (411) which measures the amount of the urine component included in before-bedtime urine that is excreted for the last time before bedtime in the day and the amount (salt) of the urine component (salt) included in overnight urine that is excreted for the first time after wake-up on the next day following a sleep; a regression equation storage unit (416) which stores a correlation (a regression equation) between the amount of the before-bedtime urine component and the amount of the overnight urine component and a total amount of the urine component included in daily urine; a daily urinary excretion calculation unit (413) which calculates the total amount of the urine component excreted in the daily urine according to the regression equation stored in the regression equation storage unit (416), using the amount of the before-bedtime urine component (salt) and the amount of the overnight urine component (salt) calculated by the urine component calculation unit (411).

摘要翻译： 提供了用于高度准确且容易地测量尿液成分的每日排泄物的每日尿排泄测量装置及其方法。 每日尿排泄量测定装置（100）包括：尿液成分计算部（411），其测量在白天睡觉前最后一次排泄的睡前尿中包含的尿成分量（盐） ）睡眠后第二天醒来后第一次排泄的隔夜尿液​​中包含的尿成分（盐） 存储睡眠前尿成分的量与过夜尿成分量之间的相关性（回归方程）和日尿中包含的尿成分的总量的回归方程式存储部（416） 尿中排泄量计算部，根据回归方程式存储部（416）中存储的回归方程，使用睡眠前尿成分的量（ 盐）和由尿成分计算单元（411）计算的过夜尿成分（盐）的量。