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公开(公告)号:US11897917B2
公开(公告)日:2024-02-13
申请号:US16650357
申请日:2017-09-27
IPC分类号: C07K1/107 , C07K1/13 , C07D205/04 , C07D207/06 , C07D207/16 , C07D211/06 , C07D295/027 , C07D403/04 , B01J27/24
CPC分类号: C07K1/1075 , B01J27/24 , C07D205/04 , C07D207/06 , C07D207/16 , C07D211/06 , C07D295/027 , C07D403/04 , C07K1/1077 , C07K1/13
摘要: Certain embodiments of the present invention relate to methods of forming and manipulating bioconjugates. Particularly, but not exclusively certain embodiments relate to methods of reversible carbon-carbon bond bioconjugation using aldol based chemical reactions at physiological conditions.
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公开(公告)号:US20170201314A1
公开(公告)日:2017-07-13
申请号:US15316768
申请日:2015-06-05
发明人: David Grace
CPC分类号: H04B7/18504 , H04L5/0035 , H04L5/006 , H04W40/22 , H04W88/04
摘要: A communication network comprising a plurality of base stations arranged to communicate data to and from a plurality of mobile devices, and at least one first base station operable to establish a first wireless communication link with a selected mobile device from the plurality of mobile devices, said first wireless communication link enabling the selected mobile device to simultaneously provide further wireless communication links to two or more mobile devices for communicating data via the first wireless communication link.
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公开(公告)号:US20160319250A1
公开(公告)日:2016-11-03
申请号:US15105502
申请日:2015-01-09
发明人: Andrew King , Ian Graham
CPC分类号: C12N9/0071 , C12N15/52 , C12N15/8243 , C12P7/02 , C12P7/26
摘要: The present disclosure relates to nucleic acids that encode polypeptides with cytochrome P450 activity involved in the biosynthesis of plant derived diterpenoids or diterpenes.
摘要翻译: 本公开涉及编码具有涉及植物来源的二萜类或双萜的生物合成的细胞色素P450活性的多肽的核酸。
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公开(公告)号:US20150200282A1
公开(公告)日:2015-07-16
申请号:US14421227
申请日:2013-07-25
发明人: Atsufumi Hirohata
IPC分类号: H01L29/66 , H01L29/20 , H01L29/82 , H01L29/778
CPC分类号: H01L29/66984 , H01L27/228 , H01L29/20 , H01L29/778 , H01L29/82 , H01L31/101
摘要: There are provided with a source part made of a ferromagnetic material magnetized in a first direction, a drain part made of a ferromagnetic material magnetized in the first direction, and separated from and arranged in parallel to the source part, a channel part arranged between the source part and the drain part, and bonded with the source part and the drain part directly or through a tunnel layer, and a circularly polarized light irradiation part that irradiates the channel part with circularly polarized light for controlling a direction of spin of the channel part.
摘要翻译: 设置有由沿第一方向磁化的铁磁材料制成的源极部分,由沿第一方向磁化的铁磁材料制成的漏极部分,并且与源极部分分离并平行布置;沟道部分, 源极部分和漏极部分,并且直接或通过隧道层与源极部分和漏极部分接合;以及圆偏振光照射部分,其利用圆偏振光照射通道部分,以控制沟道部分的旋转方向 。
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公开(公告)号:US20200317723A1
公开(公告)日:2020-10-08
申请号:US16650357
申请日:2017-09-27
IPC分类号: C07K1/107 , C07K1/13 , C07D207/06 , C07D207/16 , C07D295/027 , C07D403/04 , C07D211/06 , C07D205/04
摘要: Certain embodiments of the present invention relate to methods of forming and manipulating bioconjugates. Particularly, but not exclusively certain embodiments relate to methods of reversible carbon-carbon bond bioconjugation using aldol based chemical reactions at physiological conditions.
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公开(公告)号:US20200268284A1
公开(公告)日:2020-08-27
申请号:US16726643
申请日:2019-12-24
发明人: Stephen Smith
摘要: A device is disclosed to assist in the determination of the presence and type of dyskinesia in a patient. The device includes a sensor, removably attachable to a patient's body, such as on a limb or torso, the sensor being capable of detecting 3-D motion. Data generated by the sensor is transferred to and retained in a data retention means. A processing means is included to process the generated data, along with a look-up table of processed data for already known dyskinesia conditions for comparison, the processing means employs an evolutionary algorithm in the classification of the data. Output means display the diagnosed condition to a user.
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公开(公告)号:US20190106684A1
公开(公告)日:2019-04-11
申请号:US16082383
申请日:2017-03-13
发明人: Ian Graham , Andrew King
摘要: The present disclosure relates to nucleic acids that encode enzyme activities involved in the synthesis of lathyranes, intermediates in the synthesis of lathyranes and also compounds derived from lathyranes such as tiglianes, daphnanes and ingenanes; cells transformed with the nucleic acid molecules and vectors comprising the nucleic acid molecules.
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公开(公告)号:US10246688B2
公开(公告)日:2019-04-02
申请号:US15105502
申请日:2015-01-09
发明人: Andrew King , Ian Graham
摘要: The present disclosure relates to nucleic acids that encode polypeptides with cytochrome P450 activity involved in the biosynthesis of plant derived diterpenoids or diterpenes.
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公开(公告)号:US20180362992A1
公开(公告)日:2018-12-20
申请号:US16065421
申请日:2017-01-09
发明人: Robert White
摘要: The disclosure relates to recombinant protein expression systems comprising genetically modified cells wherein the cells are transformed or transfected with tRNA genes to reduce base mismatch due to genetic degeneracy in the genetic code.
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公开(公告)号:US10006010B2
公开(公告)日:2018-06-26
申请号:US15304455
申请日:2015-05-15
发明人: Thilo Winzer , Ian Graham , Tracy Carol Walker
CPC分类号: C12N9/0071 , C07K2319/00 , C12N9/0004 , C12N9/0077 , C12N15/8243 , C12P17/12
摘要: This disclosure relates to the isolation of a nucleic acid molecule[s] that encode a novel cytochrome P450 and an oxidoreductase from a Papaver somniferum [P. somniferum] cultivar, transgenic cells transformed with said nucleic acid molecule and sequence variants thereof; and including methods for the production of intermediates in the production of morphinans.
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