公开(公告)号：US20090142853A1

公开(公告)日：2009-06-04

申请号：US11719534

申请日：2006-08-10

申请人： Brian Herbert Warrington ,  Christopher Kevin Hoyle ,  Theresa Jane Pell ,  David Alan Pardoe

发明人： Brian Herbert Warrington ,  Christopher Kevin Hoyle ,  Theresa Jane Pell ,  David Alan Pardoe

IPC分类号： G01N21/64

CPC分类号： B01L3/502784 ,  B01L3/50273 ,  B01L3/502738 ,  B01L3/502776 ,  B01L2200/0636 ,  B01L2200/0673 ,  B01L2200/12 ,  B01L2300/0654 ,  B01L2300/0867 ,  B01L2300/165 ,  B01L2400/0487

摘要： A microfluidic system comprising: at least one microfluidic channel, the inner surface of which is fluorinated or fluorous; and a pump for supplying a flow of an aqueous medium containing chemical reagents or assay components to said microfluidic channel. Preferably, the apparatus further comprises a supply of a non-aqueous medium which is compatible with the surface of the microfluidic channel but immiscible with the aqueous medium, such as a perfluorocarbon solvent, for forming a sheath around the flowing aqueous medium whereby the aqueous medium is suspended away from the surface of the microfluidic channel. Also provided are methods for carrying out a chemical reaction or a biological assay in the microfluidic systems of the subject matter disclosed herein.

摘要翻译： 一种微流体系统，包括：至少一个微流体通道，其内表面是氟化的或含氟的; 以及用于向所述微流体通道提供含有化学试剂或测定组分的水性介质的流的泵。 优选地，该设备还包括与微流体通道的表面相容但不与水性介质例如全氟化碳溶剂混溶的非水介质的供应，用于在流动的水性介质周围形成护套，由此水性介质 被悬挂在微流体通道的表面之外。 还提供了在本文公开的主题的微流体系统中进行化学反应或生物测定的方法。

公开(公告)号：US20100011842A1

公开(公告)日：2010-01-21

申请号：US11719533

申请日：2006-08-10

申请人： Christopher Kevin Hoyle ,  Theresa Jane Pell ,  Stephanie Yuk Fan Wong Hawkes ,  Brian Herbert Warrington

发明人： Christopher Kevin Hoyle ,  Theresa Jane Pell ,  Stephanie Yuk Fan Wong Hawkes ,  Brian Herbert Warrington

IPC分类号： G01N33/00

CPC分类号： G01N33/557

摘要： Biochemical Assay Methods. There is described a method for determining a value that allows the effect that a compound has on a target to be compared with the effect that another compound has on the target, which method comprises adding the compound, at a concentration which continuously varies with time, to a flow of the target. The method can be carried out using a microfluidic system.

摘要翻译： 生化测定方法。 描述了一种用于确定化合物对靶标的影响与另一化合物对靶标的影响进行比较的值的方法，该方法包括以随时间连续变化的浓度添加化合物， 到目标的流动。 该方法可以使用微流体系统进行。