公开(公告)号：US10750738B2

公开(公告)日：2020-08-25

申请号：US12099687

申请日：2008-04-08

申请人： Robert Fishman ,  Robert Havener ,  Ihab Abdel Fattah ,  Anas Abdelazim ,  Scott Newell ,  Thomas H. Bishop ,  Tamer Khayal ,  Stanley Kyi ,  Ron Taylor ,  Doug Harriott ,  Matthew De Remer ,  Paul Murray ,  John Sullivan ,  Mark Anderson ,  Richard Bringham ,  Michael Van Driel ,  Waleed Hassanein

发明人： Robert Fishman ,  Robert Havener ,  Ihab Abdel Fattah ,  Anas Abdelazim ,  Scott Newell ,  Thomas H. Bishop ,  Tamer Khayal ,  Stanley Kyi ,  Ron Taylor ,  Doug Harriott ,  Matthew De Remer ,  Paul Murray ,  John Sullivan ,  Mark Anderson ,  Richard Bringham ,  Michael Van Driel ,  Waleed Hassanein

IPC分类号： C12Q1/02 ,  C12M1/00 ,  A01N1/02

摘要： Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.

公开(公告)号：US4596281A

公开(公告)日：1986-06-24

申请号：US414041

申请日：1982-09-02

申请人： Thomas H. Bishop

发明人： Thomas H. Bishop

IPC分类号： B22C9/04 ,  B22C9/10 ,  B22C9/24 ,  B22C21/14 ,  B22D33/04

CPC分类号： B22C21/14 ,  B22C9/10 ,  B22C9/106

摘要： An improved core is adapted to extend axially through the central portion of a mold cavity in which an airfoil or other article is formed. The core is used to form cooling passages as the airfoil is cast in the mold cavity. The core has an elongated cantilevered center section which is disposed within a main or base section. A metallic pin member extends from a free end portion of the cantilevered center section of the core to the main section of the core to hold the free end portion of the cantilevered center section against movement relative to the main section.

摘要翻译： 改进的芯适于轴向延伸穿过其中形成有翼型或其它制品的模腔的中心部分。 当机翼被铸造在模腔中时，芯用于形成冷却通道。 芯部具有细长的悬臂中心部分，其设置在主部分或基部部分内。 金属销构件从芯的悬臂中心部分的自由端部延伸到芯的主要部分，以保持悬臂中心部分的自由端部相对于主要部分的运动。