摘要:
A push-to-talk over cellular (PoC) system is provided in which a negative indication-to-speak may be delivered to a requesting unit when the requested wireless unit is not available. In one embodiment of the instant invention, a first wireless unit is paged in response to receiving a request from the second wireless unit to transmit a message to the first wireless unit. A page response signal is received from the first wireless unit, and the negative indication-to-speak to the second wireless unit is delivered to the second wireless unit in response to receiving the page response signal.
摘要:
The method described herein is useful in a push-to-talk over cellular (PoC) system to provide an accurate but low-latency indication-to-speak. Generally, the method may be referred to as a page-event confirmed indication-to-speak. The page-event confirmed indication-to-speak accurately confirms a targeted but dormant mobile station is within radio reach by first sending a paging message to the dormant mobile station. When the dormant mobile station responds to the page message, an indication-to-speak is delivered to an initiating mobile station to indicate to the user that he/she may now speak.
摘要:
The present invention relates to tumor immunotherapy, in particular to tumor vaccination, using chimeric proteins comprising all or a portion of a hepatitis B virus core antigen protein and an amino acid sequence comprising an epitope derived from the extracellular portion of a tumor-associated antigen. In particular, the present invention provides virus-like particles comprising said chimeric proteins, which are useful for eliciting a humoral immune response in a subject against the tumor-associated antigen, in particular against cells carrying said tumor-associated antigen on their surface, wherein the tumor-associated antigen is a self-protein in said subject.
摘要:
The present invention relates to tumor immunotherapy, in particular to tumor vaccination, using chimeric proteins comprising all or a portion of a hepatitis B virus core antigen protein and an amino acid sequence comprising an epitope derived from the extracellular portion of a tumor-associated antigen. In particular, the present invention provides virus-like particles comprising said chimeric proteins, which are useful for eliciting a humoral immune response in a subject against the tumor-associated antigen, in particular against cells carrying said tumor-associated antigen on their surface, wherein the tumor-associated antigen is a self-protein in said subject.