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    Controlling resorption of bioresorbable medical implant material
    5.
    发明授权
    Controlling resorption of bioresorbable medical implant material 有权
    控制生物可吸收的医用植入材料的吸收

    公开(公告)号：US06913765B2

    公开(公告)日：2005-07-05

    申请号：US09813780

    申请日：2001-03-21

    申请人： Jianmin Li ,  Samuel Baldwin ,  Tim Harrah

    发明人： Jianmin Li ,  Samuel Baldwin ,  Tim Harrah

    IPC分类号： A61L27/00 ,  A61F2/02 ,  A61L27/40 ,  A61L27/58 ,  A61L31/12 ,  A61L31/14

    CPC分类号： A61L31/148 ,  A61B17/12113 ,  A61F2/0004 ,  A61F2/02 ,  A61F2/04 ,  A61F2210/0004 ,  A61F2210/009 ,  A61L27/40 ,  A61L27/58 ,  A61L29/085 ,  A61L29/148 ,  A61L29/16 ,  A61L31/10 ,  A61L31/12 ,  A61L31/16 ,  A61L2300/00

    摘要： The resorption of a medical implant can be controlled with the use of particles embedded in a resorbable bulk material forming the implant or portion thereof. The implant can be removed from a body of a mammal by natural biological mechanisms after use. The resorption of the implant can involve swelling and/or hydrolyzing of the particles within the implant upon contact with a body fluid such that porosity and flow of fluid within the bulk material of the implant is increased. Resorption of the implant may also involve the use of particles with magnetic properties embedded within the implant such that an applied magnetic field causes the particles to vibrate within the bulk material thereby increasing the porosity and thus the flow of fluid, hence facilitating resorption of the implant. The resorption rate of the implant can be controlled by modulating swelling, hydrolysis, or movement of the embedded particles.

    摘要翻译： 可以通过使用嵌入到形成植入物或其部分的可再吸收散装材料中的颗粒来控制医用植入物的吸收。 植入物可以在使用后通过天然生物学机制从哺乳动物的身体中去除。 植入物的吸收可以包括在与体液接触时使植入物内的颗粒溶胀和/或水解，使得植入物的体积材料内的流体的孔隙率和流量增加。 植入物的再吸收还可以涉及使用具有嵌入在植入物内的磁特性的颗粒，使得所施加的磁场使得颗粒在体材料内振动，从而增加孔隙率，从而增加流体的流动，从而促进植入物的再吸收 。 植入物的吸收速率可通过调节嵌入颗粒的溶胀，水解或运动来控制。

    Controlling resorption of bioresorbable medical implant material by application of microwave, ultrasound or radiofrequencies
    6.
    发明授权
    Controlling resorption of bioresorbable medical implant material by application of microwave, ultrasound or radiofrequencies 有权
    通过应用微波，超声或射频来控制生物可吸收的医用植入材料的吸收

    公开(公告)号：US08318195B2

    公开(公告)日：2012-11-27

    申请号：US12960185

    申请日：2010-12-03

    申请人： Jianmin Li ,  Samuel Baldwin ,  Tim Harrah

    发明人： Jianmin Li ,  Samuel Baldwin ,  Tim Harrah

    IPC分类号： A61F2/02

    CPC分类号： A61L31/148 ,  A61B17/12113 ,  A61F2/0004 ,  A61F2/02 ,  A61F2/04 ,  A61F2210/0004 ,  A61F2210/009 ,  A61L27/40 ,  A61L27/58 ,  A61L29/085 ,  A61L29/148 ,  A61L29/16 ,  A61L31/10 ,  A61L31/12 ,  A61L31/16 ,  A61L2300/00

    摘要： The resorption of a medical implant can be controlled with the use of particles embedded in a resorbable bulk material forming the implant or portion thereof. The implant can be removed from a body of a mammal by natural biological mechanisms after use. The resorption of the implant can involve swelling and/or hydrolyzing of the particles within the implant upon contact with a body fluid such that porosity and flow of fluid within the bulk material of the implant is increased. Resorption of the implant may also involve the use of particles with magnetic properties embedded within the implant such that an applied magnetic field causes the particles to vibrate within the bulk material thereby increasing the porosity and thus the flow of fluid, hence facilitating resorption of the implant. The resorption rate of the implant can be controlled by modulating swelling, hydrolysis, or movement of the embedded particles.

    摘要翻译： 可以通过使用嵌入到形成植入物或其部分的可再吸收散装材料中的颗粒来控制医用植入物的吸收。 植入物可以在使用后通过天然生物学机制从哺乳动物的身体中去除。 植入物的吸收可以包括在与体液接触时使植入物内的颗粒溶胀和/或水解，使得植入物的体积材料内的流体的孔隙率和流量增加。 植入物的再吸收还可以涉及使用具有嵌入在植入物内的磁特性的颗粒，使得所施加的磁场使得颗粒在体材料内振动，从而增加孔隙率，从而增加流体的流动，从而促进植入物的再吸收 。 植入物的吸收速率可通过调节嵌入颗粒的溶胀，水解或运动来控制。

    Controlling resorption of bioresorbable medical implant material
    7.
    发明授权
    Controlling resorption of bioresorbable medical implant material 失效
    控制生物可吸收的医用植入材料的吸收

    公开(公告)号：US07910125B2

    公开(公告)日：2011-03-22

    申请号：US12072371

    申请日：2008-02-26

    申请人： Jianmin Li ,  Samuel Baldwin ,  Tim Harrah

    发明人： Jianmin Li ,  Samuel Baldwin ,  Tim Harrah

    IPC分类号： A61F2/02

    CPC分类号： A61L31/148 ,  A61B17/12113 ,  A61F2/0004 ,  A61F2/02 ,  A61F2/04 ,  A61F2210/0004 ,  A61F2210/009 ,  A61L27/40 ,  A61L27/58 ,  A61L29/085 ,  A61L29/148 ,  A61L29/16 ,  A61L31/10 ,  A61L31/12 ,  A61L31/16 ,  A61L2300/00

    摘要： The resorption of a medical implant can be controlled with the use of particles embedded in a resorbable bulk material forming the implant or portion thereof. The implant can be removed from a body of a mammal by natural biological mechanisms after use. The resorption of the implant can involve swelling and/or hydrolyzing of the particles within the implant upon contact with a body fluid such that porosity and flow of fluid within the bulk material of the implant is increased. Resorption of the implant may also involve the use of particles with magnetic properties embedded within the implant such that an applied magnetic field causes the particles to vibrate within the bulk material thereby increasing the porosity and thus the flow of fluid, hence facilitating resorption of the implant. The resorption rate of the implant can be controlled by modulating swelling, hydrolysis, or movement of the embedded particles.

    摘要翻译： 可以通过使用嵌入到形成植入物或其部分的可再吸收散装材料中的颗粒来控制医用植入物的吸收。 植入物可以在使用后通过天然生物学机制从哺乳动物的身体中去除。 植入物的吸收可以包括在与体液接触时使植入物内的颗粒溶胀和/或水解，使得植入物的体积材料内的流体的孔隙率和流量增加。 植入物的再吸收还可以涉及使用具有嵌入在植入物内的磁特性的颗粒，使得所施加的磁场使得颗粒在体材料内振动，从而增加孔隙率，从而增加流体的流动，从而促进植入物的再吸收 。 植入物的吸收速率可通过调节嵌入颗粒的溶胀，水解或运动来控制。

    Controlling resorption of bioresorbable medical implant material
    8.
    发明申请
    Controlling resorption of bioresorbable medical implant material 失效
    控制生物可吸收的医用植入材料的吸收

    公开(公告)号：US20080152692A1

    公开(公告)日：2008-06-26

    申请号：US12072371

    申请日：2008-02-26

    申请人： Jianmin Li ,  Samuel Baldwin ,  Tim Harrah

    发明人： Jianmin Li ,  Samuel Baldwin ,  Tim Harrah

    IPC分类号： A61L27/54 ,  A61L27/14 ,  A61F2/02

    CPC分类号： A61L31/148 ,  A61B17/12113 ,  A61F2/0004 ,  A61F2/02 ,  A61F2/04 ,  A61F2210/0004 ,  A61F2210/009 ,  A61L27/40 ,  A61L27/58 ,  A61L29/085 ,  A61L29/148 ,  A61L29/16 ,  A61L31/10 ,  A61L31/12 ,  A61L31/16 ,  A61L2300/00

    摘要： The resorption of a medical implant can be controlled with the use of particles embedded in a resorbable bulk material forming the implant or portion thereof. The implant can be removed from a body of a mammal by natural biological mechanisms after use. The resorption of the implant can involve swelling and/or hydrolyzing of the particles within the implant upon contact with a body fluid such that porosity and flow of fluid within the bulk material of the implant is increased. Resorption of the implant may also involve the use of particles with magnetic properties embedded within the implant such that an applied magnetic field causes the particles to vibrate within the bulk material thereby increasing the porosity and thus the flow of fluid, hence facilitating resorption of the implant. The resorption rate of the implant can be controlled by modulating swelling, hydrolysis, or movement of the embedded particles.

    摘要翻译： 可以通过使用嵌入到形成植入物或其部分的可再吸收散装材料中的颗粒来控制医用植入物的吸收。 植入物可以在使用后通过天然生物学机制从哺乳动物的身体中去除。 植入物的吸收可以包括在与体液接触时使植入物内的颗粒溶胀和/或水解，使得植入物的体积材料内的流体的孔隙率和流量增加。 植入物的再吸收还可以涉及使用具有嵌入在植入物内的磁特性的颗粒，使得所施加的磁场使得颗粒在体材料内振动，从而增加孔隙率，从而增加流体的流动，从而促进植入物的再吸收 。 植入物的吸收速率可通过调节嵌入颗粒的溶胀，水解或运动来控制。