公开(公告)号：US09387278B2

公开(公告)日：2016-07-12

申请号：US13126451

申请日：2009-09-24

申请人： Takayuki Miyakoshi ,  Toshimasa Tokuno ,  Tomoya Kitano ,  Kazutaka Yoshino ,  Yasuo Seki

发明人： Takayuki Miyakoshi ,  Toshimasa Tokuno ,  Tomoya Kitano ,  Kazutaka Yoshino ,  Yasuo Seki

IPC分类号： A61M1/10 ,  A61L29/14 ,  A61M1/36 ,  A61M1/12

CPC分类号： A61L29/146 ,  A61M1/1008 ,  A61M1/12 ,  A61M1/122 ,  A61M1/127 ,  A61M1/3653 ,  A61M1/3659

摘要： The present invention relates to an inflow cannula for blood circulatory assist devices, having a robust structure and possessing a thrombus anchoring effect. Furthermore, the inflow cannula for blood circulatory assist devices does not deform or exhibit loss of dimensional accuracy during the manufacture process. These features are achieved by a porous structure formed of one or more linear elements or of a porous shaped article.

摘要翻译： 本发明涉及一种血液循环辅助装置的流入套管，其具有坚固的结构并且具有血栓锚固效果。 此外，血液循环辅助装置的流入插管在制造过程中不会变形或显示尺寸精度的损失。 这些特征通过由一个或多个线性元件或多孔成形制品形成的多孔结构来实现。

公开(公告)号：US20130102834A1

公开(公告)日：2013-04-25

申请号：US13449453

申请日：2012-04-18

申请人： Keiichiro KANESHIMA ,  Takayuki MIYAKOSHI ,  Tomoya KITANO ,  Hideki KANEBAKO ,  Shinji KOBAYASHI ,  Koshi ADACHI ,  Koki KANDA ,  Daisuke SUZUKI

发明人： Keiichiro KANESHIMA ,  Takayuki MIYAKOSHI ,  Tomoya KITANO ,  Hideki KANEBAKO ,  Shinji KOBAYASHI ,  Koshi ADACHI ,  Koki KANDA ,  Daisuke SUZUKI

IPC分类号： A61M1/10 ,  F16J15/34 ,  F04D29/08 ,  F16C33/04

CPC分类号： F04D29/046 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/102 ,  A61M1/122 ,  F04D29/026 ,  F05D2300/211 ,  F16C33/043 ,  F16C2206/42 ,  F16C2316/18

摘要： Provided is a slide device which can reduce a frictional force more than a conventional slide device when used in an aqueous liquid containing a blood component. In a slide device which includes: a fixed-side slide member having a slide surface; and a rotary-side slide member having a slide surface, the slide device being used in an aqueous liquid containing a blood component in a state where the slide surface of the fixed-side slide member and the slide surface of the rotary-side slide member face each other in an opposed manner, at least one of the fixed-side slide member and the rotary-side slide member is formed of a member which is made of a material which contains silicon and has hydrate of silicon oxide on the slide surface thereof.

摘要翻译： 提供一种滑动装置，当在含有血液成分的含水液体中使用时，能够比常规的滑动装置更多地减小摩擦力。 一种滑动装置，包括：具有滑动面的固定侧滑动构件; 以及具有滑动面的旋转侧滑动部件，所述滑动装置用于在所述固定侧滑动部件的滑动面和所述旋转侧滑动部件的滑动面的状态下含有血液成分的水性液体 以相对的方式彼此面对，固定侧滑动构件和旋转侧滑动构件中的至少一个由在其滑动表面上由含有硅并具有氧化硅水合物的材料制成的构件形成 。

公开(公告)号：US06792138B2

公开(公告)日：2004-09-14

申请号：US09841036

申请日：2001-04-25

申请人： Naoki Hasegawa ,  Sayaka Konno ,  Naruto Shinkai ,  Tomoya Kitano ,  Motoyasu Sagawa ,  Masami Sato ,  Akira Sakurada

发明人： Naoki Hasegawa ,  Sayaka Konno ,  Naruto Shinkai ,  Tomoya Kitano ,  Motoyasu Sagawa ,  Masami Sato ,  Akira Sakurada

IPC分类号： G06K900

CPC分类号： A61B1/2676 ,  A61B1/0623 ,  A61B5/0059

摘要： A method of forming an image of detailed cilium wrapped by mucus which exists in the epithelial layer of a cellular structure of a bronchus, where the method includes the steps of: irradiating an illumination light to the epithelial layer; generating Fresnel reflected light; irradiating the Fresnel reflected light to an image pick-up optical system; enlarging the Fresnel reflected light by the image pick-up optical system so that the enlarged Fresnel reflected light can be received by the image pick-up element; scanning at a velocity which is more than the velocity of motion of the cilium by the image pick-up element; transmitting image information from the image pick-up element to an observable medium with the naked eye; and displaying the image of detailed cilium by the observable medium.

摘要翻译： 一种存在于支气管细胞结构的上皮层中的由粘液包裹的详细的纤毛的图像的方法，其中该方法包括以下步骤：向上皮层照射照明光; 产生菲涅尔反射光; 将菲涅耳反射光照射到图像拾取光学系统; 通过摄像光学系统放大菲涅尔反射光，使得放大的菲涅耳反射光能够被摄像元件接收; 以大于图像拾取元件的纤毛的运动速度的速度扫描; 将图像信息从图像拾取元件传送到肉眼可观察的介质; 并通过可观察的介质显示详细的纤毛的图像。

公开(公告)号：US08568288B2

公开(公告)日：2013-10-29

申请号：US13449453

申请日：2012-04-18

申请人： Keiichiro Kaneshima ,  Takayuki Miyakoshi ,  Tomoya Kitano ,  Hideki Kanebako ,  Shinji Kobayashi ,  Koshi Adachi ,  Koki Kanda ,  Daisuke Suzuki

发明人： Keiichiro Kaneshima ,  Takayuki Miyakoshi ,  Tomoya Kitano ,  Hideki Kanebako ,  Shinji Kobayashi ,  Koshi Adachi ,  Koki Kanda ,  Daisuke Suzuki

IPC分类号： A61N1/362

CPC分类号： F04D29/046 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/102 ,  A61M1/122 ,  F04D29/026 ,  F05D2300/211 ,  F16C33/043 ,  F16C2206/42 ,  F16C2316/18

摘要： Provided is a slide device which can reduce a frictional force more than a conventional slide device when used in an aqueous liquid containing a blood component. In a slide device which includes: a fixed-side slide member having a slide surface; and a rotary-side slide member having a slide surface, the slide device being used in an aqueous liquid containing a blood component in a state where the slide surface of the fixed-side slide member and the slide surface of the rotary-side slide member face each other in an opposed manner, at least one of the fixed-side slide member and the rotary-side slide member is formed of a member which is made of a material which contains silicon and has hydrate of silicon oxide on the slide surface thereof.

摘要翻译： 提供一种滑动装置，当在含有血液成分的含水液体中使用时，能够比常规的滑动装置更多地减小摩擦力。 一种滑动装置，包括：具有滑动面的固定侧滑动构件; 以及具有滑动面的旋转侧滑动部件，所述滑动装置用于在所述固定侧滑动部件的滑动面和所述旋转侧滑动部件的滑动面的状态下含有血液成分的水性液体 以相对的方式彼此面对，固定侧滑动构件和旋转侧滑动构件中的至少一个由在其滑动表面上由含有硅并具有氧化硅水合物的材料制成的构件形成 。

公开(公告)号：US20110112354A1

公开(公告)日：2011-05-12

申请号：US12997288

申请日：2009-04-15

申请人： Takashi Nishimura ,  Daisuke Ogawa ,  Tomoya Kitano

发明人： Takashi Nishimura ,  Daisuke Ogawa ,  Tomoya Kitano

IPC分类号： A61M1/10

CPC分类号： A61M1/1086 ,  A61M1/008 ,  A61M1/1005 ,  A61M1/101 ,  A61M1/1025 ,  A61M1/12 ,  A61M1/122 ,  A61M2205/3334 ,  A61M2230/04 ,  A61N1/362

摘要： Provided is an artificial heart control device for controlling a blood pump which assists flow of blood in a heart, the artificial heart control device including: a timing detection part which is configured to detect reference timing within a cardiac cycle of the heart; and a blood pump control part which is configured to control a rotational speed of the blood pump, wherein the blood pump control part controls, with reference to the reference timing detected by the timing detection part, the rotational speed of the blood pump such that the rotational speed becomes a rotational speed corresponding to a predetermined control pattern. According to the present invention, it is possible to provide an artificial heart control device, an artificial heart system and an artificial heart control method which can provide a load control optimum for the recovery of functions of a patient's own heart.

摘要翻译： 提供一种人造心脏控制装置，用于控制有助于心脏中血液流动的血液泵，所述人造心脏控制装置包括：定时检测部，其被配置为检测心脏心脏周期内的参考定时; 以及血泵控制部，其被配置为控制所述血液泵的旋转速度，其中，所述血液泵控制部，参照由所述定时检测部检测出的基准时刻，控制所述血液泵的旋转速度， 旋转速度成为对应于预定控制模式的旋转速度。 根据本发明，可以提供一种人造心脏控制装置，人造心脏系统和人造心脏控制方法，其可以提供对于恢复患者自身心脏的功能最佳的负荷控制。

公开(公告)号：US20060020242A1

公开(公告)日：2006-01-26

申请号：US10969228

申请日：2004-10-20

申请人： Kenji Yamazaki ,  Tomoya Kitano ,  Takeshi Nakayama

发明人： Kenji Yamazaki ,  Tomoya Kitano ,  Takeshi Nakayama

IPC分类号： A61M31/00

CPC分类号： A61M39/12 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/12 ,  A61M1/122 ,  A61M1/3653 ,  A61M1/3659 ,  A61M2205/04 ,  F16L33/225

摘要： The present invention provides an artificial blood vessel system which can suppress the occurrence of the stagnation of a blood flow and, eventually, the occurrence of the thrombus, can enhance the reliability of the connection, and can prolong the lifetime of the artificial blood connecting structure. In the artificial blood vessel system which includes an artificial blood vessel, a tubular connecting member which is connected with the artificial blood vessel, and connecting assist means for strengthening the connection between the artificial blood vessel and the tubular connecting member, the connecting assist means is configured to be capable of bringing the artificial blood vessel into pressure contact with the tubular connecting member not only along the radial direction of the tubular connecting member but also at an artificial-blood-vessel-side distal end of the tubular connecting member.

摘要翻译： 本发明提供一种能够抑制血流停滞的发生，最终导致血栓发生的人造血管系统，能够提高连接的可靠性，能够延长人造血液连接结构的寿命 。 在包括人造血管的人造血管系统中，与人造血管连接的管状连接构件和用于加强人造血管与管状连接构件之间的连接的连接辅助装置，连接辅助装置 被配置为能够使人造血管不仅沿着管状连接构件的径向而且在管状连接构件的人造血管侧远端与管状连接构件压力接触。

公开(公告)号：US09440012B2

公开(公告)日：2016-09-13

申请号：US14388264

申请日：2012-03-27

申请人： Takayuki Miyakoshi ,  Shinji Kobayashi ,  Hideki Kanebako ,  Tomoya Kitano

发明人： Takayuki Miyakoshi ,  Shinji Kobayashi ,  Hideki Kanebako ,  Tomoya Kitano

IPC分类号： A61N1/362 ,  A61M1/10 ,  A61M1/12

CPC分类号： A61M1/1005 ,  A61M1/101 ,  A61M1/1086 ,  A61M1/122 ,  A61M2205/3334

摘要： A ventricular assist blood pump of the present invention includes: a rotational part having an impeller; and a housing which houses the rotational part therein. In the ventricular assist blood pump, a difference between a maximum flow rate and a minimum flow rate of a liquid in a state where the ventricular assist blood pump is connected to a liquid-discharge source which discharges the liquid while increasing and decreasing the flow rate of the liquid at a fixed cycle is 40% or more of a difference between the maximum flow rate and the minimum flow rate of the liquid in a state where the ventricular assist blood pump is not connected to the liquid-discharge source. A ventricular assist blood pump of the present invention can suppress the degree at which the health of a user deteriorates during long-term use compared to a conventional ventricular assist blood pump.

摘要翻译： 本发明的心室辅助血泵包括：具有叶轮的旋转部; 以及容纳旋转部的壳体。 在心室辅助血液泵中，在将心室辅助血液泵连接到排出液体的液体排出源的同时增加和减少流量的状态下，液体的最大流量与最小流量之间的差值 在室内辅助血液泵未连接到液体排出源的状态下，液体的最大流量与最小流量之差为40％以上。 本发明的心室辅助血液泵与以往的心室辅助型血液泵相比，能够抑制长时间使用者的健康状况恶化的程度。

公开(公告)号：US20150297812A1

公开(公告)日：2015-10-22

申请号：US14388264

申请日：2012-03-27

申请人： Takayuki Miyakoshi ,  Shinji Kobayashi ,  Hideki Kanebako ,  Tomoya Kitano

发明人： Takayuki Miyakoshi ,  Shinji Kobayashi ,  Hideki Kanebako ,  Tomoya Kitano

IPC分类号： A61M1/10 ,  A61M1/12

CPC分类号： A61M1/1005 ,  A61M1/101 ,  A61M1/1086 ,  A61M1/122 ,  A61M2205/3334

摘要： A ventricular assist blood pump of the present invention includes: a rotational part having an impeller; and a housing which houses the rotational part therein. In the ventricular assist blood pump, a difference between a maximum flow rate and a minimum flow rate of a liquid in a state where the ventricular assist blood pump is connected to a liquid-discharge source which discharges the liquid while increasing and decreasing the flow rate of the liquid at a fixed cycle is 40% or more of a difference between the maximum flow rate and the minimum flow rate of the liquid in a state where the ventricular assist blood pump is not connected to the liquid-discharge source. A ventricular assist blood pump of the present invention can suppress the degree at which the health of a user deteriorates during long-term use compared to a conventional ventricular assist blood pump.

摘要翻译： 本发明的心室辅助血泵包括：具有叶轮的旋转部; 以及容纳旋转部的壳体。 在心室辅助血液泵中，在将心室辅助血液泵连接到排出液体的液体排出源的同时增加和减少流量的状态下，液体的最大流量与最小流量之间的差值 在室内辅助血液泵未连接到液体排出源的状态下，液体的最大流量与最小流量之差为40％以上。 本发明的心室辅助血液泵与以往的心室辅助型血液泵相比，能够抑制长时间使用者的健康状况恶化的程度。

公开(公告)号：US09125977B2

公开(公告)日：2015-09-08

申请号：US12997288

申请日：2009-04-15

申请人： Takashi Nishimura ,  Daisuke Ogawa ,  Tomoya Kitano

发明人： Takashi Nishimura ,  Daisuke Ogawa ,  Tomoya Kitano

IPC分类号： A61N1/362 ,  A61M1/10 ,  A61M1/00 ,  A61M1/12

CPC分类号： A61M1/1086 ,  A61M1/008 ,  A61M1/1005 ,  A61M1/101 ,  A61M1/1025 ,  A61M1/12 ,  A61M1/122 ,  A61M2205/3334 ,  A61M2230/04 ,  A61N1/362

摘要： Provided is an artificial heart control device for controlling a blood pump which assists flow of blood in a heart, the artificial heart control device including: a timing detection part which is configured to detect reference timing within a cardiac cycle of the heart; and a blood pump control part which is configured to control a rotational speed of the blood pump, wherein the blood pump control part controls, with reference to the reference timing detected by the timing detection part, the rotational speed of the blood pump such that the rotational speed becomes a rotational speed corresponding to a predetermined control pattern. According to the present invention, it is possible to provide an artificial heart control device, an artificial heart system and an artificial heart control method which can provide a load control optimum for the recovery of functions of a patient's own heart.

摘要翻译： 提供一种人造心脏控制装置，用于控制有助于心脏中血液流动的血液泵，所述人造心脏控制装置包括：定时检测部，其被配置为检测心脏心脏周期内的参考定时; 以及血泵控制部，其被配置为控制所述血液泵的旋转速度，其中，所述血液泵控制部，参照由所述定时检测部检测出的基准时刻，控制所述血液泵的旋转速度， 旋转速度成为对应于预定控制模式的旋转速度。 根据本发明，可以提供一种人造心脏控制装置，人造心脏系统和人造心脏控制方法，其可以提供对于恢复患者自身心脏的功能最佳的负荷控制。

公开(公告)号：US20150051437A1

公开(公告)日：2015-02-19

申请号：US14388242

申请日：2012-03-27

申请人： Takayuki Miyakoshi ,  Shinji Kobayashi ,  Hideki Kanebako ,  Tomoya Kitano

发明人： Takayuki Miyakoshi ,  Shinji Kobayashi ,  Hideki Kanebako ,  Tomoya Kitano

IPC分类号： A61M1/10 ,  A61M1/12

CPC分类号： A61M1/1008 ,  A61M1/1005 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1086 ,  A61M1/122 ,  A61M2205/3334 ,  A61M2240/00

摘要： A ventricular assist system includes: a ventricular assist blood pump provided with a rotational part having an impeller and a housing which houses the rotational part therein; an introduction-side artificial vessel which introduces a liquid into the ventricular assist blood pump; and a delivery-side artificial vessel which delivers the liquid from the ventricular assist system. In the ventricular assist system, a difference between a maximum flow rate and a minimum flow rate of a liquid in a state where the ventricular assist system is connected to a liquid-discharge source which discharges the liquid while increasing and decreasing the flow rate of the liquid at a fixed cycle is 40% or more of a difference between the maximum flow rate and the minimum flow rate of the liquid in a state where the ventricular assist system is not connected to the liquid-discharge source.

摘要翻译： 心室辅助系统包括：心室辅助血液泵，其具有旋转部分，所述旋转部分具有叶轮和容纳所述旋转部分的壳体; 将液体引入心室辅助血液泵的引入侧人造血管; 以及从心室辅助系统输送液体的输送侧人造血管。 在心室辅助系统中，在心室辅助系统连接到排出液体的液体排出源的状态下，液体的最大流量和最小流量之间的差异，同时增加和减少流体的流量 固定循环的液体在心室辅助系统未连接到液体排出源的状态下，液体的最大流量与最小流量之差为40％以上。