摘要:
The present invention provides a method for diagnosing cancer, predicting a disease outcome or response to therapy in a patient sample. The method involves isolating a circulating tumor cell (CTC), for example, a viable CTC, from a sample using a parylene microfilter device comprising a membrane filter having or consisting of a parylene substrate, which has an array of holes with a predetermined shape and size; and detecting and quantifying telomerase activity in blood circulating tumor cells. The invention further provides methods of using cells live-captured in various applications.
摘要:
Method for relieving cough using an effective antitussive chemical compound belonging to stemoamide or tuberostemospironine and method for manufacturing pharmaceutical compositions for treating or relieving cough in human and animal subjects which including a stemoamide or tuberostemospironine compound. In addition, the antitussive property of the compounds provides a method for assessing the quality of herbs traditionally used in treating cough by analyzing the content of the effective chemical ingredient, i.e., compounds of stemoamide type and/or tuterostemospironine type. It further provides a method for identifying medicinal herbs which may be used for relieving cough by phytochemical determination of the existence of compounds that are of stemoamide or tuterostemospironine type.
摘要:
Molecules comprising aminooxy groups are provided, wherein the aminooxy groups provide attachment sites for the covalent attachment of other molecules. In one embodiment, polyoxyethylene molecules comprising aminooxy groups are provided that can be conjugated to wide variety of biologically active molecules including poly(amino acids). In another embodiment, valency platform molecules comprising aminooxy groups are provided. The aminooxy groups can be used to form covalent bonds with biological molecules such as poly(amino acids). The aminooxy groups can, for example, react with poly(amino acids) modified to contain carbonyl groups, such as glyoxyl groups, to form a conjugate of the valency platform molecule and the biologically active molecule via an oxime bond. The valency platform molecules comprising aminooxy groups are advantageously reactive in the formation of conjugates, and they also can be readily synthesized to form a composition with very low polydispersity.
摘要:
A method for determining values of anisotropic model parameters of a Tilted Transversely Isotropic (TTI) Earth model, the method including obtaining an initial TTI earth model that substantially flattens common-imaging-point gathers and substantially ties seismic data to well data; inputting checkshot data and/or VSP data to determine updated values of Vp0 near the well locations; determining an incremental improvement Δδ; extrapolating the relative change Δδ from near-well locations to the entire three dimensional TTI earth model; determining updated values of Vp0=Vp0 (1−Δδ); inputting near-to-mid-offset/angle and mid-to-far-offset/angle residual moveout information; and providing updated values of δ and η.
摘要:
Method for relieving cough using an effective antitussive chemical compound belonging to stemoamide or tuberostemospironine and method for manufacturing pharmaceutical compositions for treating or relieving cough in human and animal subjects which including a stemoamide or tuberostemospironine compound. In addition, the antitussive property of the compounds provides a method for assessing the quality of herbs traditionally used in treating cough by analyzing the content of the effective chemical ingredient, i.e., compounds of stemoamide type and/or tuterostemospironine type. It further provides a method for identifying medicinal herbs which may be used for relieving cough by phytochemical determination of the existence of compounds that are of stemoamide or tuterostemospironine type.
摘要:
A module of a terminal block (100) comprises a body (104) having an input configured to be coupled to an input wire and an output configured to be coupled to a plurality of output wires, a conductive element disposed within the input, and a plurality of terminals, each terminal having a first portion and a second portion configured to be coupled to an output wire, wherein the first portions of the plurality of terminals are nested together to achieve a single conductive structure, and wherein the conductive element is configured to engage and compress the input wire against the single conductive structure.
摘要:
An approach is provided for associating interest tags with media items based on social diffusions among users. The media tagging platform processes and/or facilitates a processing of one or more user profiles to determine one or more interest tags relating to one or more users, captured at one or more user devices to determine one or more frequencies of the one or more signals. Next, the media tagging platform determines one or more social diffusions of the one or more media items among the one or more users. Then, the media tagging platform causes, at least in part, an association of the one or more media items with the one or more interest tags based, at least in part, on the one or more social diffusions.
摘要:
A module of a terminal block (100) comprises a body (104) having an input configured to be coupled to an input wire and an output configured to be coupled to a plurality of output wires, a conductive element disposed within the input, and a plurality of terminals, each terminal having a first portion and a second portion configured to be coupled to an output wire, wherein the first portions of the plurality of terminals are nested together to achieve a single conductive structure, and wherein the conductive element is configured to engage and compress the input wire against the single conductive structure.
摘要:
A method for determining values of anisotropic model parameters of a Tilted Transversely Isotropic (TTI) Earth model, the method including obtaining an initial TTI earth model that substantially flattens common-imaging-point gathers and substantially ties seismic data to well data; inputting checkshot data and/or VSP data to determine updated values of Vp0 near the well locations; determining an incremental improvement Δδ; extrapolating the relative change Δδ from near-well locations to the entire three dimensional TTI earth model; determining updated values of Vp0=Vp0 (1−Δδ); inputting near-to-mid-offset/angle and mid-to-far-offset/angle residual moveout information; and providing updated values of δ and η.
摘要:
A method for selecting and configuring network supernodes includes (i) in a first set period T1, each node, other than a control node in a network, regularly sending information on interactions between the node and other nodes to the control node; and (ii) in a second set period T2, the control node dividing the nodes into a plurality of node clusters according to the received information on interactions among the nodes and selecting supernodes from each node cluster, where each node belonging uniquely to a node cluster.