METHODS AND DESIGN OF MEMBRANE FILTERS
    3.
    发明申请
    METHODS AND DESIGN OF MEMBRANE FILTERS 审中-公开
    膜过滤器的方法与设计

    公开(公告)号:US20110294206A1

    公开(公告)日:2011-12-01

    申请号:US13078870

    申请日:2011-04-01

    申请人: YU-CHONG TAI Bo Lu

    发明人: YU-CHONG TAI Bo Lu

    IPC分类号: C12N5/09

    CPC分类号: G01N33/5011 B01D65/10

    摘要: The present invention provides methods for designing a filtration systems for capturing viable tumor cells, such as circulating tumor cells at high efficiency and high viability. The methods involve development of a set of “key engineering design parameters” that are crucial to achieve high tumor cell viability. These important design parameters include the filter geometry design, fluid delivery method, drive pressure and filtration time.

    摘要翻译: 本发明提供了用于设计用于捕获活肿瘤细胞的过滤系统的方法,例如高效率和高活力的循环肿瘤细胞。 这些方法涉及开发一组对于实现高肿瘤细胞活力至关重要的“关键工程设计参数”。 这些重要的设计参数包括过滤器几何设计,流体输送方法,驱动压力和过滤时间。

    DIAGNOSABLE MAGNETIC SWITCH ASSEMBLY
    4.
    发明申请
    DIAGNOSABLE MAGNETIC SWITCH ASSEMBLY 审中-公开
    诊断磁力开关总成

    公开(公告)号:US20100198464A1

    公开(公告)日:2010-08-05

    申请号:US12696086

    申请日:2010-01-29

    IPC分类号: A47C7/62 H01H36/00

    摘要: A diagnosable magnetic switch assembly and method for determining a seat occupant. A network in the assembly includes a resistor in series with a magnetic switch, and a resistor in parallel with the series combination. Such an arrangement provides distinct assembly resistance values when the magnetic switch is open or closed, and thereby provides a means for diagnosing the operational state of the diagnosable magnetic switch assembly. The diagnosable magnetic switch assembly may be included in a seat occupant indicator system that embeds the seat occupant indicator system and a magnet in a cushion of a seat assembly. When the seat assembly is occupied, the magnet is separated from the seat occupant indicator system by a sufficient distance so the seat occupant indicator system is in an open state. When an occupant sits in the seat assembly, the magnet and the seat occupant indicator system are brought closer together so that the magnetic field operate the seat occupant indicator system to a closed state. A controller measures the assembly resistance values to determine if the seat assembly is empty, occupied, or if an assembly fault state is occurring.

    摘要翻译: 一种用于确定座椅乘客的可诊断磁开关组件和方法。 组件中的网络包括与磁开关串联的电阻器和与串联组合并联的电阻器。 这种布置在磁性开关打开或关闭时提供不同的组装电阻值,从而提供用于诊断可诊断磁性开关组件的操作状态的装置。 可诊断的磁性开关组件可以包括在将座椅乘员指示器系统和磁体嵌入座椅组件的坐垫中的座椅乘员指示器系统中。 当座椅组件被占用时,磁体与座椅乘员指示器系统分离足够的距离,使得座椅乘员指示器系统处于打开状态。 当乘员坐在座椅组件中时,磁体和座椅乘员指示器系统被更靠近在一起,使得磁场将座椅乘员指示器系统操作到关闭状态。 控制器测量组合电阻值,以确定座椅组件是否为空,占用,或者是否发生装配故障状态。

    Targeted Advertisements to Social Contacts
    5.
    发明申请
    Targeted Advertisements to Social Contacts 有权
    针对社交联系人的广告

    公开(公告)号:US20100093317A1

    公开(公告)日:2010-04-15

    申请号:US12248720

    申请日:2008-10-09

    IPC分类号: H04W4/00

    摘要: Targeted advertisements to social contacts is described. In embodiment(s), social contacts can be correlated based on messaging interactions between mobile communication devices that are associated with the social contacts. Feedback about an advertisement can be received from mobile communication devices that are associated with the social contacts, and the advertisement can then be targeted to one or more of the social contacts based on the feedback about the advertisement.

    摘要翻译: 描述了针对社交联系人的目标广告。 在实施例中,社交联系人可以基于与社交联系人相关联的移动通信设备之间的消息交互相关联。 可以从与社交联系人相关联的移动通信设备接收关于广告的反馈,然后可以基于关于广告的反馈将广告定位到一个或多个社交联系人。

    Method for fabricating a nonvolatile memory cell
    7.
    发明授权
    Method for fabricating a nonvolatile memory cell 有权
    非易失性存储单元的制造方法

    公开(公告)号:US07309632B1

    公开(公告)日:2007-12-18

    申请号:US11735440

    申请日:2007-04-14

    IPC分类号: H01L21/8247

    摘要: A method of fabricating a nonvolatile memory cell includes providing a substrate with a trench, with a sidewall where a tunnel oxide layer and a floating gate are successively formed, forming a control gate in the trench, performing a high density plasma deposition process to form an HDP oxide layer on the top surface of control gate.

    摘要翻译: 一种制造非易失性存储单元的方法包括提供具有沟槽的衬底,其中连续形成隧道氧化物层和浮栅的侧壁,在沟槽中形成控制栅极,执行高密度等离子体沉积工艺以形成 HDP氧化层在控制门的顶面。

    ULTRATHIN PARYLENE-C SEMIPERMEABLE MEMBRANES FOR BIOMEDICAL APPLICATIONS
    9.
    发明申请
    ULTRATHIN PARYLENE-C SEMIPERMEABLE MEMBRANES FOR BIOMEDICAL APPLICATIONS 有权
    ULTRATHIN PARYLENE-C可生物医学应用的可切割膜

    公开(公告)号:US20130143326A1

    公开(公告)日:2013-06-06

    申请号:US13355426

    申请日:2012-01-20

    IPC分类号: C12N5/071 C12N5/077 C23C16/44

    摘要: Thin parylene C membranes having smooth front sides and ultrathin regions (e.g., 0.01 μm to 5 μm thick) interspersed with thicker regions are disclosed. The back sides of the membranes can be rough compared with the smooth front sides. The membranes can be used in vitro to grow monolayers of cells in a laboratory or in vivo as surgically implantable growth layers, such as to replace the Bruch's membrane in the eye. The thin regions of parylene are semipermeable to allow for proteins in serum to pass through, and the thick regions give mechanical support for handling by a surgeon. The smooth front side allows for monolayer cell growth, and the rough back side helps prevents cells from attaching there.

    摘要翻译: 公开了具有较厚区域散布的具有光滑前侧和超薄区域(例如,0.01μm至5μm厚)的薄聚对二甲苯C膜。 与光滑的前侧相比,膜的背面可能是粗糙的。 膜可以在体外用于在实验室或体内生长细胞的单层,作为外科手术植入的生长层,例如替代眼睛中的Bruch膜。 聚对二甲苯的薄区域是半渗透性的,以允许血清中的蛋白质通过,并且厚区域给予外科医生处理的机械支持。 光滑的前侧允许单层细胞生长,粗糙的背面有助于防止细胞附着在那里。

    METHOD FOR CANCER DETECTION, DIAGNOSIS AND PROGNOSIS
    10.
    发明申请
    METHOD FOR CANCER DETECTION, DIAGNOSIS AND PROGNOSIS 有权
    癌症检测,诊断和预防方法

    公开(公告)号:US20110053152A1

    公开(公告)日:2011-03-03

    申请号:US12784446

    申请日:2010-05-20

    摘要: The present invention provides a method for diagnosing cancer, predicting a disease outcome or response to therapy in a patient sample. The method involves isolating a circulating tumor cell (CTC), for example, a viable CTC, from a sample using a parylene microfilter device comprising a membrane filter having or consisting of a parylene substrate, which has an array of holes with a predetermined shape and size; and detecting and quantifying telomerase activity in blood circulating tumor cells. The invention further provides methods of using cells live-captured in various applications.

    摘要翻译: 本发明提供一种用于诊断癌症的方法,预测患者样品中的疾病结果或对治疗的反应。 该方法包括使用聚对二甲苯微型过滤器装置从样品中分离循环肿瘤细胞(CTC),例如可行的CTC,所述聚对二甲苯微型过滤器包括具有具有预定形状的孔阵列的具有聚对二甲苯衬底或由聚对二甲苯衬底组成的膜过滤器, 尺寸; 并检测和定量血液循环肿瘤细胞中的端粒酶活性。 本发明还提供了使用在各种应用中实时捕获的细胞的方法。