公开(公告)号：US20100069683A1

公开(公告)日：2010-03-18

申请号：US12583943

申请日：2009-08-28

申请人： Takashi Miki ,  Junichi Hori ,  Toshihide Takemoto ,  Noriyuki Utsumi ,  Takeaki Katayama ,  Masahito Watanabe ,  Kunihiko Murata

发明人： Takashi Miki ,  Junichi Hori ,  Toshihide Takemoto ,  Noriyuki Utsumi ,  Takeaki Katayama ,  Masahito Watanabe ,  Kunihiko Murata

IPC分类号： C07C37/00

CPC分类号： C07B53/00 ,  B01J31/1805 ,  B01J31/2295 ,  B01J2231/643 ,  B01J2531/0238 ,  B01J2531/822 ,  B01J2531/827 ,  C07F17/02

摘要： The present invention provides an asymmetric reduction catalyst effective in preparing optically-active alcohol compounds having various functional groups, and a process for preparing optically-active alcohol compounds using said asymmetric reduction catalyst.The organic metal compound of the present invention is represented by the following general formula (1): wherein R1 and R2 may be mutually identical or different, and are an alkyl group, a phenyl group, a naphthyl group, a cycloalkyl group, or an alicyclic ring formed by binding R1 and R2, which may have a substituent; R3 is a hydrogen atom or an alkyl group; Cp is a cyclopentadienyl group, which may have a substituent, bound to M1 via a π bond; X1 is a halogen atom or a hydrido group; M1 is rhodium or iridium; and * denotes asymmetric carbon.

摘要翻译： 本发明提供了一种有效地制备具有各种官能团的光学活性醇化合物的不对称还原催化剂，以及使用该不对称还原催化剂制备光学活性醇化合物的方法。 本发明的有机金属化合物由以下通式（1）表示：其中R1和R2可以相同或不同，为烷基，苯基，萘基，环烷基或 通过结合可以具有取代基的R 1和R 2形成的脂环; R3是氢原子或烷基; Cp是可以具有取代基的环戊二烯基，其通过a和p结合到M1; 键; X1是卤原子或氢环; M1是铑或铱; 和*表示不对称碳。

公开(公告)号：US20110319671A1

公开(公告)日：2011-12-29

申请号：US13170347

申请日：2011-06-28

申请人： Takeaki Katayama ,  Toshihide Takemoto ,  Kunihiko Murata

发明人： Takeaki Katayama ,  Toshihide Takemoto ,  Kunihiko Murata

IPC分类号： C07C29/143

CPC分类号： C07C29/143 ,  C07B2200/07 ,  C07C31/38

摘要： The problem to be resolved by the present invention is to provide a method for efficiently synthesizing optically active lower aliphatic alcohols that have difficulty in separation from organic solvents, without using a special reactor.The present invention relates to a method for producing an optically active aliphatic alcohol having a fluorine atom at α position, wherein an optically active alcohol is produced by reacting an aliphatic ketone having a fluorine atom at α position in water using a formate, under the presence of an asymmetric catalyst represented by general formula (1) and an acid.

摘要翻译： 本发明要解决的问题是提供一种高效合成难以与有机溶剂分离的光学活性低级脂族醇的方法，而不使用特殊的反应器。 本发明涉及一种在α位具有氟原子的光学活性脂肪醇的制造方法，其特征在于，在甲酸盐存在下，使甲酸酯在水中的α位置具有氟原子的脂肪族酮， 的由通式（1）表示的不对称催化剂和酸。

公开(公告)号：US4320189A

公开(公告)日：1982-03-16

申请号：US191965

申请日：1980-09-29

申请人： Tadashi Taguchi ,  Toshihide Takemoto ,  Noboru Fujikawa ,  Mitsuo Kohno

发明人： Tadashi Taguchi ,  Toshihide Takemoto ,  Noboru Fujikawa ,  Mitsuo Kohno

IPC分类号： G03C1/00 ,  C08F2/00 ,  C08F2/50 ,  G03F7/085 ,  H05K3/00 ,  H05K3/18 ,  H05K3/38 ,  G03C1/68

CPC分类号： H05K3/0076 ,  C08F2/50 ,  G03F7/085 ,  H05K2203/124 ,  H05K3/184 ,  H05K3/389 ,  Y10S430/121

摘要： A novel photopolymerizable composition comprising (a) a non-gaseous ethylenically unsaturated compound, (b) a thermoplastic organic polymer binder, (c) a photopolymerization initiator and (d) a specific s-triazine compound provides improved adhesion of a photopolymer prepared therefrom to a substrate even in aqueous plating or etching solutions.

摘要翻译： 一种新型的可光聚合组合物，其包含（a）非气态烯键式不饱和化合物，（b）热塑性有机聚合物粘合剂，（c）光聚合引发剂和（d）特定的s-三嗪化合物，提供了由其制备的光聚合物与 即使在水性电镀或蚀刻溶液中也是基材。

公开(公告)号：US08558033B2

公开(公告)日：2013-10-15

申请号：US13170347

申请日：2011-06-28

申请人： Takeaki Katayama ,  Toshihide Takemoto ,  Kunihiko Murata

发明人： Takeaki Katayama ,  Toshihide Takemoto ,  Kunihiko Murata

IPC分类号： C07C29/143

CPC分类号： C07C29/143 ,  C07B2200/07 ,  C07C31/38

摘要： The problem to be resolved by the present invention is to provide a method for efficiently synthesizing optically active lower aliphatic alcohols that have difficulty in separation from organic solvents, without using a special reactor.The present invention relates to a method for producing an optically active aliphatic alcohol having a fluorine atom at α position, wherein an optically active alcohol is produced by reacting an aliphatic ketone having a fluorine atom at α position in water using a formate, under the presence of an asymmetric catalyst represented by general formula (1) and an acid.

摘要翻译： 本发明要解决的问题是提供一种高效合成难以与有机溶剂分离的光学活性低级脂族醇的方法，而不使用特殊的反应器。 本发明涉及一种在α位具有氟原子的光学活性脂族醇的制造方法，其中通过使甲酸钠在水中的α位具有氟原子的脂族酮与甲酸酯反应来制备光学活性醇， 的由通式（1）表示的不对称催化剂和酸。

公开(公告)号：US20090062573A1

公开(公告)日：2009-03-05

申请号：US12218874

申请日：2008-07-18

申请人： Takashi Miki ,  Junichi Hori ,  Toshihide Takemoto ,  Noriyuki Utsumi ,  Takeaki Katayama ,  Masahito Watanabe ,  Kunihiko Murata

发明人： Takashi Miki ,  Junichi Hori ,  Toshihide Takemoto ,  Noriyuki Utsumi ,  Takeaki Katayama ,  Masahito Watanabe ,  Kunihiko Murata

IPC分类号： C07F15/00 ,  C07C29/143 ,  C07C37/00

CPC分类号： C07B53/00 ,  B01J31/1805 ,  B01J31/2295 ,  B01J2231/643 ,  B01J2531/0238 ,  B01J2531/822 ,  B01J2531/827 ,  C07F17/02

摘要： The present invention provides an asymmetric reduction catalyst effective in preparing optically-active alcohol compounds having various functional groups, and a process for preparing optically-active alcohol compounds using said asymmetric reduction catalyst.The organic metal compound of the present invention is represented by the following general formula (1): wherein R1 and R2 may be mutually identical or different, and are an alkyl group, a phenyl group, a naphthyl group, a cycloalkyl group, or an alicyclic ring formed by binding R1 and R2, which may have a substituent; R3 is a hydrogen atom or an alkyl group; Cp is a cyclopentadienyl group, which may have a substituent, bound to M1 via a π bond; X1 is a halogen atom or a hydrido group; M1 is rhodium or iridium; and * denotes asymmetric carbon.

摘要翻译： 本发明提供了一种有效地制备具有各种官能团的光学活性醇化合物的不对称还原催化剂，以及使用该不对称还原催化剂制备光学活性醇化合物的方法。 本发明的有机金属化合物由以下通式（1）表示：其中R1和R2可以相同或不同，为烷基，苯基，萘基，环烷基或 通过结合可以具有取代基的R 1和R 2形成的脂环; R3是氢原子或烷基; Cp是可以具有取代基的环戊二烯基，其通过π键与M1结合; X1是卤原子或氢环; M1是铑或铱; 和*表示不对称碳。