公开(公告)号：US20110034466A1

公开(公告)日：2011-02-10

申请号：US12989516

申请日：2009-04-23

申请人： Hitoshi Fujita ,  Toshio Kanai ,  Satoki Imai

发明人： Hitoshi Fujita ,  Toshio Kanai ,  Satoki Imai

IPC分类号： A61K31/5377 ,  C07D413/10 ,  A61P29/00

CPC分类号： C07D277/20 ,  C07D277/42 ,  C07D417/10

摘要： Disclosed is a five-membered ring compound represented by formula (1) or a pharmaceutically acceptable salt thereof. The compound inhibits infiltration of leukocytes including eosinophils and lymphocytes, and is effective as a drug for treating various inflammations. The compound is highly safe and can be administered for a long period. A pharmaceutical product containing the five-membered ring compound or a pharmaceutically acceptable salt thereof is also disclosed. (In the formula, R1 represents a halogen atom or a phenyl group which may be substituted by a C1-C3 alkyl group or a C1-C3 alkoxy group; R2 represents a C1-C3 alkylene group which may be substituted by a C1-C3 alkyl group or a carbonyl group; R3 represents a C1-C3 alkyl group; R4 and R5 independently represent a hydrogen atom or a C1-C3 alkyl group, or —N(R4)R5 may represent a morpholino group which may be substituted by a C1-C3 alkyl group; Y2 represents a C2-C4 alkylene group; and R6 represents a hydrogen atom, a halogen atom, a C1-C3 alkyl group or a C1-C3 alkoxy group.)

摘要翻译： 公开了由式（1）表示的五元环化合物或其药学上可接受的盐。 该化合物抑制嗜酸性粒细胞和淋巴细胞等白细胞的浸润，作为治疗各种炎症的药物是有效的。 该化合物是高度安全的，可以长期施用。 还公开了含有五元环化合物或其药学上可接受的盐的药物。 （式中，R1表示卤原子或可被C1-C3烷基或C1-C3烷氧基取代的苯基; R2表示可被C1-C3取代的C1-C3亚烷基 烷基或羰基; R3表示C1-C3烷基; R4和R5独立地表示氢原子或C1-C3烷基，或-N（R4）R5可以表示可以被 C1-C3烷基; Y2表示C2-C4亚烷基; R6表示氢原子，卤素原子，C1-C3烷基或C1-C3烷氧基）。

公开(公告)号：US06847601B2

公开(公告)日：2005-01-25

申请号：US09921837

申请日：2001-08-03

申请人： Toshio Kanai ,  Mikiko Roji

发明人： Toshio Kanai ,  Mikiko Roji

IPC分类号： G11B7/005 ,  G11B20/10 ,  G11B20/18 ,  H03M7/14 ,  G11B7/00

CPC分类号： G11B20/10212 ,  G11B7/005 ,  G11B20/10046 ,  G11B20/10425 ,  G11B20/18 ,  G11B2020/1457

摘要： To correct a bit shift of binary data read from a medium and further enable correction of a bit error caused by mis-correction of the bit shift, a data recovery apparatus according to the present invention comprises: circuits for respectively correcting time at an intersection of a read signal and a slice signal; and a circuit for generating gray bits representing a time cell including an intersection, the time of the intersection being uncorrected and a time cell adjacent to the time cell, positioned in the direction of the intersection being shifted for correction.

摘要翻译： 为了校正从介质读取的二进制数据的位移，并且进一步使得能够校正由位移的错误校正引起的位误差，根据本发明的数据恢复装置包括：用于分别校正时间在 读信号和切片信号; 以及电路，用于生成表示包括交叉点的时间单元的灰度位，交叉点未修正的时间和与时间单元相邻的时间单元位于交叉点的方向上，以便进行修正。

公开(公告)号：US06246653B1

公开(公告)日：2001-06-12

申请号：US09209789

申请日：1998-12-11

申请人： Toshio Kanai ,  Takeo Yasuda ,  Kazuhiro Tsuruta ,  Wataru Ichihara

发明人： Toshio Kanai ,  Takeo Yasuda ,  Kazuhiro Tsuruta ,  Wataru Ichihara

IPC分类号： G11B700

CPC分类号： G11B7/005 ,  G11B20/10009

摘要： A method and apparatus for reducing the effect of inter-wave interference on signals read from a storage medium and to precisely digitize the read signals are described. An apparatus for digitizing a signal read from a storage medium according to an embodiment of the invention, comprises: a peak detector, for detecting a peak value for an amplitude of a signal read from the storage medium; a threshold value determiner, for employing the peak value obtained by the peak detector to determine a compensation value that is used for compensating for the effect of inter-wave interference on the signal, and for employing the threshold value calculated by the conventional method and the compensation value to determine a compensated threshold value; and a digitization circuit, for digitizing the signal by using the threshold value determined by the threshold value determiner. Optionally an interpolator may be used to obtain more accurate peak values which occur between sample points.

摘要翻译： 描述了一种用于减少波形干扰对从存储介质读取的信号的影响并精确数字化读取信号的方法和装置。 根据本发明的实施例的用于数字化从存储介质读取的信号的装置包括：峰值检测器，用于检测从存储介质读取的信号的幅度的峰值; 阈值确定器，用于使用由峰值检测器获得的峰值来确定用于补偿波前干扰对信号的影响的补偿值，以及采用通过常规方法计算的阈值和 补偿值以确定补偿阈值; 以及数字化电路，用于通过使用由阈值确定器确定的阈值来对信号进行数字化。 可选地，可以使用内插器来获得在采样点之间出现的更准确的峰值。

公开(公告)号：US6092145A

公开(公告)日：2000-07-18

申请号：US576027

申请日：1995-12-21

申请人： Yuji Kigami ,  Kohji Yamada ,  Toshio Kanai ,  Kazuyuki Ishibashi

发明人： Yuji Kigami ,  Kohji Yamada ,  Toshio Kanai ,  Kazuyuki Ishibashi

IPC分类号： G06F3/06 ,  G06F12/08 ,  G11B20/10 ,  G06F12/00 ,  G06F13/00

CPC分类号： G06F3/0613 ,  G06F12/0866 ,  G06F3/0656 ,  G06F3/0674 ,  G06F2212/312

摘要： A disk drive system comprising a sector buffer having a plurality of segments for storing data and a controller for classifying data and for storing a portion of the classified data in a segment of a sector buffer such that said portion of the classified data stored in said segment is not stored in any other segment in the sector buffer.

摘要翻译： 一种磁盘驱动器系统，包括具有用于存储数据的多个段的扇区缓冲器和用于对数据进行分类并将分类数据的一部分存储在扇区缓冲器的段中的控制器，使得存储在所述段中的所述分类数据的所述部分 不存储在扇区缓冲区中的任何其他段中。

公开(公告)号：US5161241A

公开(公告)日：1992-11-03

申请号：US813061

申请日：1991-12-23

申请人： Toshio Kanai

发明人： Toshio Kanai

IPC分类号： H04N3/18

CPC分类号： H04N3/18

摘要： A power supply circuit for a CRT display device includes a low-voltage power supply switching circuit for supplying power to a horizontal oscillation circuit of the CRT display device, and a high-voltage power supply switching circuit for supplying power to high-voltage circuits of the CRT display device. The low-voltage power supply switching circuit includes an oscillator and a switching transistor. The oscillator is triggered by an output of the horizontal oscillation circuit, and the conductive state of the switching transistor is controlled according to an output of the oscillator. The high-voltage power supply switching circuit includes a switching transistor. The conductive state of the switching transistor of the high-voltage power supply switching circuit is controlled according to an output of the low-voltage power supply switching circuit. As such, the switching operations of the low-voltage and high-voltage power supply switching circuits is carried out at a same frequency and in synchronism with the output of the horizontal oscillation circuit.

摘要翻译： 用于CRT显示装置的电源电路包括用于向CRT显示装置的水平振荡电路供电的低压电源切换电路和用于向CRT显示装置的高电压电路供电的高压电源切换电路 CRT显示设备。 低压电源开关电路包括振荡器和开关晶体管。 振荡器由水平振荡电路的输出触发，并根据振荡器的输出来控制开关晶体管的导通状态。 高压电源开关电路包括开关晶体管。 根据低电压电源切换电路的输出，控制高压电源切换电路的开关晶体管的导通状态。 因此，低电压和高压电源开关电路的切换操作以与水平振荡电路的输出相同的频率和同步地进行。

公开(公告)号：US4855686A

公开(公告)日：1989-08-08

申请号：US201220

申请日：1988-06-02

申请人： Ichiro Ishihara ,  Toshio Kanai

发明人： Ichiro Ishihara ,  Toshio Kanai

IPC分类号： H03F3/45

CPC分类号： H03F3/45278 ,  H03F3/45085 ,  H03F2203/45674

摘要： Disclosed is a differential amplifier circuit which includes a first NPN transistor, a second NPN transistor, a current source connected to the emitters of the first and second NPN transistors, a first PNP load transistor having a collector connected to the collector of the first NPN transistor, a second PNP load transistor having a collector coupled to the collector of the second NPN transistor, and an FET having a gate connected to the collector of the first NPN transistor, and a source connected to the bases of the first and second PNP load transistors. A DC input current of the FET is substantially zero, and is designed to absorb a current corresponding to the gate potential of the FET, from the bases of the first and second PNP load transistors.

摘要翻译： 公开了一种差分放大器电路，其包括第一NPN晶体管，第二NPN晶体管，连接到第一和第二NPN晶体管的发射极的电流源，具有连接到第一NPN晶体管的集电极的集电极的第一PNP负载晶体管 ，具有耦合到第二NPN晶体管的集电极的集电极的第二PNP负载晶体管和具有连接到第一NPN晶体管的集电极的栅极的FET，以及连接到第一和第二PNP负载晶体管的基极的源极 。 FET的直流输入电流基本上为零，并且被设计为从第一和第二PNP负载晶体管的基极吸收对应于FET的栅极电位的电流。

公开(公告)号：US20110263550A1

公开(公告)日：2011-10-27

申请号：US13084503

申请日：2011-04-11

申请人： Toshinari Sugasawa ,  Takashi Nakajima ,  Hitoshi Fujita ,  Toshio Kanai

发明人： Toshinari Sugasawa ,  Takashi Nakajima ,  Hitoshi Fujita ,  Toshio Kanai

IPC分类号： A61K31/56 ,  A61P11/00 ,  A61K31/5377

CPC分类号： A61K31/56 ,  A61K9/10 ,  A61K31/5377 ,  C07D277/42

摘要： Disclosed is a method for the prevention and/or treatment of a chronic obstructive pulmonary disease by administrating a 5-membered cyclic compound represented by the formula below: or a pharmaceutically acceptable salt of the compound or a prodrug of the compound or salt: wherein X represents an oxygen or sulfur atom; R1 represents a hydrogen atom, a substituted or unsubstituted alkyl or the like; R2 represents a hydrogen atom, a substituted or unsubstituted alkyl or the like; Y1 represents single bond, a substituted or unsubstituted alkylene or the like; the wavy line means an (E) or (Z) coordination; R3 represents a hydrogen atom, a substituted or unsubstituted aryl or the like; Y2 represents a substituted or unsubstituted alkylene or an alkenylene; R4 represents a hydrogen atom, a substituted or unsubstituted alkanoyl or the like; and R5 represents a hydrogen atom or a substituted or unsubstituted alkyl.

摘要翻译： 本发明公开了一种预防和/或治疗慢性阻塞性肺疾病的方法，该方法是通过给予由下式表示的5元环状化合物：或化合物的药学上可接受的盐或其化合物或盐的前体药物：其中X 表示氧或硫原子; R1表示氢原子，取代或未取代的烷基等; R 2表示氢原子，取代或未取代的烷基等; Y1表示单键，取代或未取代的亚烷基等; 波浪线表示（E）或（Z）配位; R3表示氢原子，取代或未取代的芳基等; Y2表示取代或未取代的亚烷基或亚烯基; R4表示氢原子，取代或未取代的烷酰基等; 并且R 5表示氢原子或取代或未取代的烷基。

公开(公告)号：US06687068B2

公开(公告)日：2004-02-03

申请号：US10099796

申请日：2002-03-15

申请人： Toshio Kanai

发明人： Toshio Kanai

IPC分类号： G11B509

CPC分类号： G11B20/10203 ,  G11B5/02 ,  G11B20/10027

摘要： A method and system for reproducing digital data read from a storage device. A second-order differentiation of a digital signal representing the digital data is calculated to control an automatic gain control (AGC) and phase lock loop (PLL) to rapidly correct amplitude and frequency offset of the digital signal being read from the storage device.

摘要翻译： 一种用于再现从存储装置读取的数字数据的方法和系统。 计算表示数字数据的数字信号的二阶微分，以控制自动增益控制（AGC）和锁相环（PLL），以快速校正从存储装置读取的数字信号的幅度和频率偏移。

公开(公告)号：US06221935B1

公开(公告)日：2001-04-24

申请号：US09357656

申请日：1999-07-20

申请人： Yoshitomi Hashimoto ,  Toshio Kanai ,  Yutaka Furuya

发明人： Yoshitomi Hashimoto ,  Toshio Kanai ,  Yutaka Furuya

IPC分类号： C08L6706

CPC分类号： C08F283/01 ,  C04B26/18 ,  C04B2111/34 ,  C08G63/553 ,  C04B2103/0046

摘要： A resin concrete composition and its molded article are provided, the resin concrete, even with a reduced resin content, having an excellent flowability, which is an important property in a molding operation, and necessitating no shrinkage reduction agent, and the molded article having no cracks and being highly strong. The resin concrete composition comprises (A) a resin composition containing (a) an unsaturated polyester of an unsaturated acid, a di- and/or trialkylene glycol, and dicyclopentadiene and (b) a polymerizable unsaturated monomer, (B) an aggregate, and (C) a filler.

摘要翻译： 提供了一种树脂混凝土组合物及其模塑制品，树脂混凝土即使具有降低的树脂含量，具有优异的流动性，这在成型操作中是重要的特性，并且不需要减缩剂，并且模制品没有 裂缝很强。 树脂混凝土组合物包含（A）含有（a）不饱和酸的不饱和聚酯，二亚烷基二醇和二亚烷基二醇和二环戊二烯的不饱和聚酯和（b）聚合性不饱和单体的树脂组合物，（B）骨料，和 （C）填料。

公开(公告)号：US4942469A

公开(公告)日：1990-07-17

申请号：US299479

申请日：1989-01-23

申请人： Toshio Kanai

发明人： Toshio Kanai

IPC分类号： H04N5/08

CPC分类号： H04N5/08

摘要： A picture display apparatus for displaying a picture by using a composite signal including tri-state binary synchronizing signals. A first horizontal synchonizing signal comprising a positive-polarity bilevel (the two-state) signal is generated by detecting a negative-polarity peak portion of an input composite picture signal to accomplish the horizontal synchronization of a picture by use of the first horizontal synchronizing signal whereby when the horizontal synchronization is stabilized, an output pulse produced from the first horizontal synchronizing signal is utilized to extract the tri-state binary horizontal synchronizing signal from the composite picture signal during the time of the output pulse thereby accomplishing horizontal synchronization of the picture by the tri-state binary horizontal synchronizing signal in the stable condition.

摘要翻译： 一种用于通过使用包括三态二进制同步信号的复合信号显示图像的图像显示装置。 通过检测输入的合成图像信号的负极性峰值部分来产生包括正极性双电平（双态）信号的第一水平同步信号，以通过使用第一水平同步信号来实现图像的水平同步 由此当水平同步稳定时，利用从第一水平同步信号产生的输出脉冲在输出脉冲期间从复合图像信号中提取三态二进制水平同步信号，由此完成图像的水平同步 三态二进制水平同步信号处于稳定状态。