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公开(公告)号：US20230135837A1
公开(公告)日：2023-05-04
申请号：US16650070
申请日：2018-09-27
申请人： CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) , UNIVERSITE DE LILLE , UNIVERSITE DU LITTORAL COTE D'OPALE , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , TAIPEI MEDICAL UNIVERSITY
摘要： The present invention relates on a process for preparing platelet lysate fraction, said process comprising the steps of: 1) providing a platelet lysate, 2) collecting from said platelet lysate a fraction wherein the components exhibit a maximum molecular weight of 100 kDa, on a specific platelet lysate fraction and its use as a drug.
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公开(公告)号：US11744863B2
公开(公告)日：2023-09-05
申请号：US16622446
申请日：2018-06-15
申请人： CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) , UNIVERSITE DE LILLE , UNIVERSITE DU LITTORAL COTE D'OPALE , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , TAIPEI MEDICAL UNIVERSITY
CPC分类号： A61K35/19 , A61K9/0085 , A61P25/28 , C12N5/0644
摘要： Process for preparing a heat-treated pooled human platelet lysate, said process comprising the steps of: a) Providing a pooled human platelet lysate (p HPL), b) Heat-treating the pooled human platelet lysate at a temperature of 50° C. to 70° C. during 20 to 40 minutes, c) Purifying the heat-treated pooled human platelet lysate of step b).
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公开(公告)号：US11099070B2
公开(公告)日：2021-08-24
申请号：US16624123
申请日：2018-06-22
发明人： Gaël Mouret , Francis Hindle , Robin Bocquet
IPC分类号： G01J3/26 , G01N21/3586 , G02B26/00 , G01J3/02
摘要： The present disclosure relates to a high-fineness Fabry-Perot cavity (for use in the THz range) with a guide comprising lateral cavities arranged to guide an electromagnetic wave into the cavity. The invention also relates to a method for implementing a device including such a Fabry-Perot cavity.
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公开(公告)号：US10105326B2
公开(公告)日：2018-10-23
申请号：US15310364
申请日：2015-05-12
申请人： CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) , UNIVERSITE DE LILLE 2 DROIT ET SANTE , UNIVERSITE DU LITTORAL COTE D'OPALE
IPC分类号： A61K31/137 , A61K9/08 , A61P25/16 , A61K9/00
摘要： The present invention is directed to pharmaceutical solution comprising at least dopamine for use in treating Parkinson's disease, wherein said pharmaceutical solution is kept under anaerobic conditions from its formulation to its administration.
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公开(公告)号：US20190099448A1
公开(公告)日：2019-04-04
申请号：US16087471
申请日：2017-03-23
申请人： CENTRE HOSPITALER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) , UNIVERSITE DE LILLE 2 DROIT ET SANTE , UNIVERSITE DU LITTORAL COTE D'OPALE , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , TAIPEI MEDICAL UNIVERSITY
摘要： A process for preparing a modified heat-treated platelet pellet lysate, said process comprising the steps of: a) Providing a platelet pellet lysate, b) Heat-treating the platelet pellet lysate at a temperature of 55° C. to 65° C. during 20 to 40 minutes, c) Purifying the heat-treated platelet pellet lysate of step b) so as to obtain a modified heat treated platelet pellet lysate having a total protein content of less than 70% of the total protein content of the platelet pellet lysate of step a).
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公开(公告)号：US20190022034A1
公开(公告)日：2019-01-24
申请号：US16138286
申请日：2018-09-21
申请人： CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) , UNIVERSITE DE LILLE 2 DROIT ET SANTE , UNIVERSITE DU LITTORAL COTE D'OPALE
IPC分类号： A61K31/137 , A61K9/00
摘要： The present invention is directed to pharmaceutical solution comprising at least dopamine for use in treating Parkinson's disease, wherein said pharmaceutical solution is kept under anaerobic conditions from its formulation to its administration.
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公开(公告)号：US20170151193A1
公开(公告)日：2017-06-01
申请号：US15310364
申请日：2015-05-12
申请人： CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) , UNIVERSITE DE LILLE 2 DROIT ET SANTE , UNIVERSITE DU LITTORAL COTE D'OPALE
IPC分类号： A61K31/137 , A61K9/00
CPC分类号： A61K31/137 , A61K9/0019 , A61K9/0085
摘要： The present invention is directed to pharmaceutical solution comprising at least dopamine for use in treating Parkinson's disease, wherein said pharmaceutical solution is kept under anaerobic conditions from its firmation to its administration.
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