-
公开(公告)号:US10561856B2
公开(公告)日:2020-02-18
申请号:US15025623
申请日:2014-11-25
申请人: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , UNIVERSITE DE LILLE 2 DROIT ET SANTE , CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
发明人: Serge Mordon , Nacim Betrouni , Laurent Mortier
IPC分类号: A61N5/06
摘要: The system comprises: —a bundle of light fibers (11) connected to a light-emitting source (8), and both transmitting light inside the light fiber and emitting light toward a treatment volume (V), —a temperature-modifying system attached to the bundle of light fibers (11) to modify temperature in the treatment volume (V).
-
公开(公告)号:US20190033525A1
公开(公告)日:2019-01-31
申请号:US16074937
申请日:2017-02-03
申请人: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , UNIVERSITE DE LILLE 2 DROIT ET SANTE , CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
发明人: Serge MORDON , Pascal DELEPÔRTE , Nacim BETROUNI
IPC分类号: G02B6/14 , H04B10/2581
CPC分类号: G02B6/14 , H04B10/2581
摘要: An optical fiber mode scrambler adapted to give a determined bending to an optical fiber inserted in the mode scrambler, the mode scrambler having a general extension direction X, the mode scrambler having a morphology adapted to give the optical fiber a direction along X at the entry of the scrambler, and then to bend the fiber to bring the fiber substantially in the X, Y plan in the −X and Y directions, before bringing the fiber in a rotation around the X axis substantially in the Y, Z plan in the anti clockwise direction for one full rotation, and then bending the fiber to bring the fiber substantially in the X, Y plan in the −X and −Y directions, and then bending the fiber to give the optical fiber a direction along X at the exit of the scrambler.
-
公开(公告)号:US10105326B2
公开(公告)日:2018-10-23
申请号:US15310364
申请日:2015-05-12
申请人: CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) , UNIVERSITE DE LILLE 2 DROIT ET SANTE , UNIVERSITE DU LITTORAL COTE D'OPALE
IPC分类号: A61K31/137 , A61K9/08 , A61P25/16 , A61K9/00
摘要: The present invention is directed to pharmaceutical solution comprising at least dopamine for use in treating Parkinson's disease, wherein said pharmaceutical solution is kept under anaerobic conditions from its formulation to its administration.
-
公开(公告)号:US20180144661A1
公开(公告)日:2018-05-24
申请号:US15575668
申请日:2016-05-26
申请人: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , UNIVERSITE DE VALENCIENNES ET DU HAINAUT CAMBRESIS , UNIVERSITE DE LILLE 2 DROIT ET SANTE , CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
发明人: Lieven ROBBERECHT , Jean-Christophe HORNEZ , Feng CHAI , Etienne DEVEAUX , Anne LERICHE , Vincent HORNEZ , Thibault BECAVIN , Marion DEHURTEVENT
CPC分类号: G09B23/283 , A61C5/50 , A61C19/04 , G09B9/00 , G09B23/286 , G09B23/30
摘要: The present invention relates to an artificial root canal simulator based on hydroxyapatite, comprising a cavity representing a root canal, said artificial root canal simulator having a porosity of between 10% and 40% and a Vickers hardness of 50 to 200 HV, and to a method for the manufacture of an artificial root canal simulator according to the invention.
-
5.
公开(公告)号:US20230207300A1
公开(公告)日:2023-06-29
申请号:US17926730
申请日:2021-05-20
申请人: UNIVERSITE DE LILLE , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
发明人: Isabelle SALZET , Julien FRANCK , Michel SALZET , Flore HERVE
IPC分类号: H01J49/04 , H01J49/26 , G01N33/497 , H01J49/10
CPC分类号: H01J49/049 , G01N33/497 , H01J49/26 , H01J49/105
摘要: A system and method for analyzing volatile organic compounds (VOCs) adsorbed on an adsorbent membrane, by low-temperature plasma and mass spectrometry (LTP-MS). The system includes a receptacle for receiving the adsorbent membrane, a low-temperature plasma ionizer configured to emit a plasma stream in a plasma emission direction, thereby ionizing the VOCs adsorbed by the membrane and forming a VOC-laden ionized gas, and a mass spectrometer for analyzing the ionized VOCs.
-
公开(公告)号:US20230135837A1
公开(公告)日:2023-05-04
申请号:US16650070
申请日:2018-09-27
申请人: CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) , UNIVERSITE DE LILLE , UNIVERSITE DU LITTORAL COTE D'OPALE , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , TAIPEI MEDICAL UNIVERSITY
摘要: The present invention relates on a process for preparing platelet lysate fraction, said process comprising the steps of: 1) providing a platelet lysate, 2) collecting from said platelet lysate a fraction wherein the components exhibit a maximum molecular weight of 100 kDa, on a specific platelet lysate fraction and its use as a drug.
-
公开(公告)号:US11135443B2
公开(公告)日:2021-10-05
申请号:US16086228
申请日:2017-03-24
申请人: INSERM (Institut National de la Sante et de la Recherche Medicale) , Universite de Lille , Centre Hospitalier Regional et Universitaire de Lille (CHRU)
发明人: Maximilien Vermandel , Clement Dupont , Nicolas Reyns , Pascal Deleporte , Serge Mordon , Nacim Betrouni
摘要: System (1) for treatment by photodynamic therapy comprising an illuminating member (6) which comprises: —a core (35) carrying a light emitting surface (37), and —a hollow sheath (10) adapted to receive the core (35) with the light emitting surface (37) arranged within a balloon (11), the balloon (11) comprising a wall (12) which has an inner surface delimiting an internal space, and an outer surface, the wall (12) being flexible, wherein the internal space of the balloon (11) has a variable capacity, the wall (12) of the balloon (11) being elastically extendible and the balloon (11) presenting a plurality of inflated states in each of which the internal space is filled with a volume of light diffusing solution, and wherein the system further comprises a support provided with a transfer function relating the volume of light diffusing solution of each inflated state with at least one of a corresponding distribution of light power at the outer surface of the wall (12) of the balloon (11) and a corresponding time of illumination for providing a determined dose of light energy.
-
公开(公告)号:US10401567B2
公开(公告)日:2019-09-03
申请号:US16074937
申请日:2017-02-03
申请人: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , UNIVERSITE DE LILLE 2 DROIT ET SANTE , CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
发明人: Serge Mordon , Pascal Delepôrte , Nacim Betrouni
IPC分类号: G02B6/02 , G02B6/14 , H04B10/2581
摘要: An optical fiber mode scrambler adapted to give a determined bending to an optical fiber inserted in the mode scrambler, the mode scrambler having a general extension direction X, the mode scrambler having a morphology adapted to give the optical fiber a direction along X at the entry of the scrambler, and then to bend the fiber to bring the fiber substantially in the X, Y plan in the −X and Y directions, before bringing the fiber in a rotation around the X axis substantially in the Y, Z plan in the anti clockwise direction for one full rotation, and then bending the fiber to bring the fiber substantially in the X, Y plan in the −X and −Y directions, and then bending the fiber to give the optical fiber a direction along X at the exit of the scrambler.
-
公开(公告)号:US20180290981A1
公开(公告)日:2018-10-11
申请号:US16009979
申请日:2018-06-15
申请人: INSERM (Institut National de la Sante et de la Recherche Medicale) , CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) , UNIVERSITE DE LILLE 2 DROIT ET SANTE
发明人: Nicolas SERGEANT , Luc BUEE , Patricia MELNYK , Marion GAY , Nicolas LE FUR
IPC分类号: C07D219/12
摘要: The present invention relates to the compound having Formula (I) or pharmaceutically acceptable salts or solvates thereof, and its use in treating and/or preventing a Tauopathy.
-
公开(公告)号:US20160051832A1
公开(公告)日:2016-02-25
申请号:US14779710
申请日:2014-03-21
申请人: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , UNIVERSITE DE LILLE 2 DROIT ET SANTE , CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
发明人: Serge Mordon
CPC分类号: A61N5/062 , A61N5/0616 , A61N2005/063 , A61N2005/0651 , D03D1/00 , D03D1/0088 , D03D15/00 , D03D15/0011 , D10B2401/20 , D10B2403/0114 , D10B2509/00 , G02B6/001 , G02B6/3664
摘要: A medical device (1) comprising a flexible light source wherein said flexible light source comprises two or more individually manageable areas (2, 3, 4) of light emission and wherein each area (2, 3, 4) comprises a light diffuser textile comprising optical fibres (10) providing side diffusion of a light, method for its manufacture and medical uses.
摘要翻译: 一种包括柔性光源的医疗装置(1),其中所述柔性光源包括两个或更多个可单独管理的发光区域(2,3,4),并且其中每个区域(2,3,4)包括光扩散器织物,其包括 提供光的侧向扩散的光纤(10),其制造方法和医疗用途。
-
-
-
-
-
-
-
-
-