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公开(公告)号：US20240181192A1
公开(公告)日：2024-06-06
申请号：US18438696
申请日：2024-02-12
发明人： Joseph Rabin , Conor Bloomer , Paige Chan , Scott Kivitz , Peter Chen , Torrance Wang
CPC分类号： A61M16/0472 , A61M16/0465 , A61M16/0816 , A61M16/085
摘要： The present invention provides an improved percutaneous dilation tracheostomy device. The device is configured to include all of the required components to perform a percutaneous tracheotomy. The device includes a retractable needle and an extendable j-wire rather than having separate components as in typical percutaneous tracheostomy devices. The device includes a dilator section to expand the diameter of a patient's stoma. The device is further configured to allow an operator to perform a bubble test to alert the user that the tube is in the trachea. In addition, the device is generally more compact than typical emergency tracheostomy devices.
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公开(公告)号：US11896763B2
公开(公告)日：2024-02-13
申请号：US18055586
申请日：2022-11-15
发明人： Joseph Rabin , Conor Bloomer , Paige Chan , Scott Kivitz , Peter Chen , Torrance Wang
CPC分类号： A61M16/0472 , A61M16/0465 , A61M16/085 , A61M16/0816
摘要： The present invention provides an improved percutaneous dilation tracheostomy device. The device is configured to include all of the required components to perform a percutaneous tracheotomy. The device includes a retractable needle and an extendable j-wire rather than having separate components as in typical percutaneous tracheostomy devices. The device includes a dilator section to expand the diameter of a patient's stoma. The device is further configured to allow an operator to perform a bubble test to alert the user that the tube is in the trachea. In addition, the device is generally more compact than typical emergency tracheostomy devices.
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公开(公告)号：US20240001136A1
公开(公告)日：2024-01-04
申请号：US18345614
申请日：2023-06-30
发明人： Fow-Sen CHOA , L. Elliott Hong
CPC分类号： A61N2/02 , A61N2/006 , H01F27/2823
摘要： The present invention relates to angle-tuned (AT) ring coil devices to reduce the individual coil footprint and improve depth-spread characteristics of transcranial magnetic stimulation (TMS) systems. The AT coil device includes multiple stacked coils, which enhances field strength, reduces the footprint, and increases the field penetration depth by modifying its geometric distribution. Moreover, the AT coil devices demonstrated superior performance for multisite stimulation due to their smaller footprint, making them suitable for multisite stimulations of inter and intra-hemispheric brain regions with an improved spread and less electric field divergence.
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4.发明公开公开(公告)号：US20230152320A1
公开(公告)日：2023-05-18
申请号：US18055333
申请日：2022-11-14
IPC分类号： G01N33/569 , G01N29/12 , G01N29/24 , G01N33/543
CPC分类号： G01N33/56983 , G01N29/12 , G01N29/2443 , G01N33/54373 , G01N2291/014 , G01N2291/023 , G01N2333/165
摘要： An apparatus is provided for airborne pathogen detection, which includes a crystal microbalance. The apparatus includes specific capture probes that are affixed to the crystal microbalance and are designed to bind to and capture a specific pathogen, such as a virus particle. This capture causes a change in mass of the crystal microbalance that can be detected. A method is provided for airborne pathogen detection, which includes calibrating a resonant frequency of the crystal microbalance to a mass on the crystal microbalance. The method also includes a step of conjugating the antibody to the crystal microbalance. The method also includes, for each measurement time, measuring a resonant frequency of the crystal microbalance and determining a mass change due to binding of the pathogen to the detector. This mass change is then related to pathogen load in the medium. A notification is output if the viral load exceeds a predetermined threshold.
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公开(公告)号：US11523808B2
公开(公告)日：2022-12-13
申请号：US16577345
申请日：2019-09-20
发明人： James S. Gammie , Rachael Quinn , Chetan Pasrija
IPC分类号： A61B17/00 , A61B17/34 , A61B17/3207 , A61M25/01 , A61B18/00
摘要： The present invention provides transseptal puncture devices configured to access structures on the left side of the heart from the right side of the heart without requiring open-heart surgery. The devices have adjustable stiffness to enter the vasculature in a flexible, atraumatic fashion, then become rigid once in place to provide a stable platform for penetration of the fossa ovalis. The devices are further configured to controllably and stably extend a needle to puncture the FO. The devices include an indwelling blunt stylus that can extend perpendicularly from the device to increase the accuracy of placement near the fossa ovalis.
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公开(公告)号：US20220249126A1
公开(公告)日：2022-08-11
申请号：US17526616
申请日：2021-11-15
申请人： University of Maryland, Baltimore , University of Maryland Medical System LLC , Protaryx Medical Inc.
发明人： James S. GAMMIE , Philip J. HAARSTAD , David BLAESER , Ryan BAUER , Stephen ROLLER , Rachael QUINN , Chetan PASRIJA , Edwin HLAVKA
IPC分类号： A61B17/34
摘要： In some embodiments, a method includes a shaft having a side catheter guide attached thereto via a guide coupler into an inferior vena cava and a superior vena cava such that the guide coupler is disposed in a right atrium, and applying a distal force to a proximal portion of the side catheter guide such that a distal end of the side catheter guide deflects laterally about the guide coupler towards a septum. The method further includes extending a side catheter that is disposed within the side catheter guide distally from the side catheter guide towards and into contact with the septum. The method further includes, with the side catheter in contact with the septum, extending a septum penetrator that is slidably disposed within the side catheter distally from the side catheter such that the septum penetrator pierces the septum.
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公开(公告)号：US11154325B2
公开(公告)日：2021-10-26
申请号：US17315729
申请日：2021-05-10
申请人： University of Maryland, Baltimore , University of Maryland Medical System LLC , Protaryx Medical Inc.
发明人： James S. Gammie , Philip J. Haarstad , David Blaeser , Ryan Bauer , Stephen Roller , Rachael Quinn , Chetan Pasrija , Edwin Hlavka
摘要： In some embodiments, a method includes a shaft having a side catheter guide attached thereto via a guide coupler into an inferior vena cava and a superior vena cava such that the guide coupler is disposed in a right atrium, and applying a distal force to a proximal portion of the side catheter guide such that a distal end of the side catheter guide deflects laterally about the guide coupler towards a septum. The method further includes extending a side catheter that is disposed within the side catheter guide distally from the side catheter guide towards and into contact with the septum. The method further includes, with the side catheter in contact with the septum, extending a septum penetrator that is slidably disposed within the side catheter distally from the side catheter such that the septum penetrator pierces the septum.
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公开(公告)号：US20200246046A1
公开(公告)日：2020-08-06
申请号：US16858015
申请日：2020-04-24
申请人： University of Maryland, Baltimore , University of Maryland Medical System LLC , Protaryx Medical Inc.
发明人： James S. GAMMIE , Philip J. HAARSTAD , David BLAESER , Ryan BAUER , Stephen ROLLER , Rachael QUINN , Chetan PASRIJA , Edwin HLAVKA
IPC分类号： A61B17/34
摘要： In some embodiments, a method includes a shaft having a side catheter guide attached thereto via a guide coupler into an inferior vena cava and a superior vena cava such that the guide coupler is disposed in a right atrium, and applying a distal force to a proximal portion of the side catheter guide such that a distal end of the side catheter guide deflects laterally about the guide coupler towards a septum. The method further includes extending a side catheter that is disposed within the side catheter guide distally from the side catheter guide towards and into contact with the septum. The method further includes, with the side catheter in contact with the septum, extending a septum penetrator that is slidably disposed within the side catheter distally from the side catheter such that the septum penetrator pierces the septum.
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9.发明申请公开(公告)号：US20200078300A1
公开(公告)日：2020-03-12
申请号：US16568396
申请日：2019-09-12
申请人： UNIVERSITY OF MARYLAND, BALTIMORE COUNTY , UNIVERSITY OF MARYLAND, BALTIMORE , NORTHWESTERN UNIVERSITY
发明人： GREGORY SZETO , EVAN SCOTT , AMIT GOLDING , MARILYN ALLEN , NICHOLAS B. KARABIN
IPC分类号： A61K9/127 , A61K31/4706 , A61P37/06 , A61K9/107 , A61K31/52 , A61K31/573
摘要： The present invention provides for delivery of therapeutic drug in a polymeric delivery system comprising a PEG-bl-PPS di-block polymer formed in a micelle, filomicelle, or polymersome structure, wherein the structure effectively binds and/or interacts through shape-based targeting with a targeted cell type.
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公开(公告)号：US10518098B2
公开(公告)日：2019-12-31
申请号：US15300979
申请日：2015-04-02
发明人： Liyi Elliott Hong , Fow-Sen Choa
摘要： The present invention discloses methods and systems to control magnetic fields and magnetic field induced currents, and more particularly to provide stimulations within a patient's body, such as deep brain stimulation, in a non-invasive manner and with greater focus and control than has been afforded by prior known methods and systems. In accordance with certain aspects of an embodiment, an array of magnetic coils is provided and positionable about a portion of a patient's body. During operation, at least some of the magnetic coils function as DC coil pairs configured to generate a DC magnetic field, while at least some DC coil of the other magnetic coils function as transient magnetic field generators to generate an induced current within a portion of the patient's body, such as in a region of the patient's brain. The system is configured such that the DC magnetic fields may be used to manipulate the transient magnetic fields, in turn allowing significantly improved control and focus of the induced current within a specifically desired volume of interest within a patient's body.
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