公开(公告)号：US09382272B2

公开(公告)日：2016-07-05

申请号：US13145999

申请日：2010-01-22

Applicant: Kiran Kumar Kothakonda ,  Fan Wang ,  Bhaskar Reddy Guntoori ,  Minh T. N. Nguyen ,  Alfredo Paul Ceccarelli ,  Yajun Zhao ,  Uma Kotipalli ,  Sammy Chris Duncan ,  Kaarina K. Milnes ,  Kevin Wade Kells ,  Laura Kaye Montemayor

Inventor： Kiran Kumar Kothakonda ,  Fan Wang ,  Bhaskar Reddy Guntoori ,  Minh T. N. Nguyen ,  Alfredo Paul Ceccarelli ,  Yajun Zhao ,  Uma Kotipalli ,  Sammy Chris Duncan ,  Kaarina K. Milnes ,  Kevin Wade Kells ,  Laura Kaye Montemayor

IPC: C07D323/04 ,  C07D311/00 ,  C07D315/00 ,  C07D307/93 ,  C07C61/06 ,  C07C69/74 ,  C07F7/18 ,  C07C69/734 ,  C07C69/738 ,  C07C405/00 ,  C07D307/935

CPC classification number: C07F7/1892 ,  C07C69/734 ,  C07C69/738 ,  C07C405/00 ,  C07C2601/08 ,  C07D307/935

Abstract: There is provided processes for preparing Lubiprostone and intermediates thereof. Also provided are compounds, including intermediates for preparing Lubiprostone as well compositions comprising Lubiprostone and other compounds, including intermediates for preparing Lubiprostone and other compounds. (I)

Abstract translation: 提供了用于制备卢比克石及其中间体的方法。 还提供了化合物，包括用于制备柳替罗石的中间体以及包含卢比石和其它化合物的组合物，包括用于制备柳普罗石和其它化合物的中间体。 （一世）

公开(公告)号：US07834195B2

公开(公告)日：2010-11-16

申请号：US11808942

申请日：2007-06-14

Applicant: K. S. Keshava Murthy ,  Yajun Zhao ,  Allan W. Rey ,  Daqing Che ,  David A. Stradiotto ,  Uma Kotipalli

Inventor： K. S. Keshava Murthy ,  Yajun Zhao ,  Allan W. Rey ,  Daqing Che ,  David A. Stradiotto ,  Uma Kotipalli

IPC: C07D207/00

CPC classification number: C07D207/34

Abstract: Atorvastatin calcium propylene glycol solvates and processes to prepare these novel solvates which are particularly useful and suitable for pharmaceutical applications.

Abstract translation: 阿托伐他汀钙丙二醇溶剂化物并制备这些新的溶剂化物，这些新的溶剂合物特别有用并适用于药物应用。

公开(公告)号：US20080177087A1

公开(公告)日：2008-07-24

申请号：US11808942

申请日：2007-06-14

Applicant: K.S. Keshava Murthy ,  Yajun Zhao ,  Allan W. Rey ,  Daqing Che ,  David A. Stradiotto ,  Uma Kotipalli

Inventor： K.S. Keshava Murthy ,  Yajun Zhao ,  Allan W. Rey ,  Daqing Che ,  David A. Stradiotto ,  Uma Kotipalli

IPC: C07D207/30

CPC classification number: C07D207/34

Abstract: Atorvastatin calcium propylene glycol solvates and processes to prepare these novel solvates which are particularly useful and suitable for pharmaceutical applications.

Abstract translation: 阿托伐他汀钙丙二醇溶剂化物并制备这些新的溶剂化物，这些新的溶剂合物特别有用并适用于药物应用。

公开(公告)号：US20120065409A1

公开(公告)日：2012-03-15

申请号：US13145999

申请日：2010-01-22

Applicant: Kiran Kumar Kothakonda ,  Fan Wang ,  Bhaskar Reddy Guntoori ,  Minh T. N. Nguyen ,  Alfredo Paul Ceccarelli ,  Yajun Zhao ,  Uma Kotipalli ,  Sammy Chris Duncan ,  Kaarina K. Milnes ,  Kevin Wade Kells ,  Laura Kaye Montemayor

Inventor： Kiran Kumar Kothakonda ,  Fan Wang ,  Bhaskar Reddy Guntoori ,  Minh T. N. Nguyen ,  Alfredo Paul Ceccarelli ,  Yajun Zhao ,  Uma Kotipalli ,  Sammy Chris Duncan ,  Kaarina K. Milnes ,  Kevin Wade Kells ,  Laura Kaye Montemayor

IPC: C07D311/94 ,  C07F7/18 ,  C07C69/734 ,  C07D307/20 ,  C07D307/935 ,  C07C59/62

CPC classification number: C07F7/1892 ,  C07C69/734 ,  C07C69/738 ,  C07C405/00 ,  C07C2601/08 ,  C07D307/935

Abstract: There is provided processes for preparing Lubiprostone and intermediates thereof. Also provided are compounds, including intermediates for preparing Lubiprostone as well compositions comprising Lubiprostone and other compounds, including intermediates for preparing Lubiprostone and other compounds. (I)

Abstract translation: 提供了用于制备卢比克石及其中间体的方法。 还提供了化合物，包括用于制备柳替罗石的中间体以及包含卢比石和其它化合物的组合物，包括用于制备柳普罗石和其它化合物的中间体。 （一世）

公开(公告)号：US08188300B2

公开(公告)日：2012-05-29

申请号：US12946183

申请日：2010-11-15

Applicant: K.S. Keshava Murthy ,  Yajun Zhao ,  Allan W. Rey ,  Daqing Che ,  David A. Stradiotto ,  Uma Kotipalli

Inventor： K.S. Keshava Murthy ,  Yajun Zhao ,  Allan W. Rey ,  Daqing Che ,  David A. Stradiotto ,  Uma Kotipalli

IPC: C07D207/00

CPC classification number: C07D207/34

Abstract: Atorvastatin calcium propylene glycol solvates and processes to prepare these novel solvates which are particularly useful and suitable for pharmaceutical applications.

Abstract translation: 阿托伐他汀钙丙二醇溶剂化物并制备这些新的溶剂化物，这些新的溶剂合物特别有用并适用于药物应用。

公开(公告)号：US20110065931A1

公开(公告)日：2011-03-17

申请号：US12946183

申请日：2010-11-15

Applicant: K.S. Keshava Murthy ,  Yajun Zhao ,  Allan W. Rey ,  Daqing Che ,  David A. Stradiotto ,  Uma Kotipalli

Inventor： K.S. Keshava Murthy ,  Yajun Zhao ,  Allan W. Rey ,  Daqing Che ,  David A. Stradiotto ,  Uma Kotipalli

IPC: C07D207/34

CPC classification number: C07D207/34

Abstract: Atorvastatin calcium propylene glycol solvates and processes to prepare these novel solvates which are particularly useful and suitable for pharmaceutical applications.

Abstract translation: 阿托伐他汀钙丙二醇溶剂化物并制备这些新的溶剂化物，这些新的溶剂合物特别有用并适用于药物应用。