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公开(公告)号：US20230320984A1
公开(公告)日：2023-10-12
申请号：US18154349
申请日：2023-01-13
发明人： Iain Stuart , Russell Elliott , Yohan Hazot , Gareth Winckle , Ariel Margulis
IPC分类号： A61K9/06 , A61K9/00 , A61K31/519 , A61K31/133 , A61P17/00 , A61K47/44 , A61K47/06 , A61K47/14
CPC分类号： A61K9/06 , A61K9/0014 , A61K31/519 , A61K47/14 , A61P17/00 , A61K47/44 , A61K47/06 , A61K31/133
摘要： The present disclosure relates to novel topical formulations containing a tofacitinib and or a fingolimod that are useful for treating dermatological conditions, such as atopic dermatitis, psoriasis, vitiligo and eczema.
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公开(公告)号：US20210205212A1
公开(公告)日：2021-07-08
申请号：US17075217
申请日：2020-10-20
发明人： Dov Tamarkin , Meir Eini , Yohan Hazot , Mitchell Shirvan , Tal Hetzroni Kedem , Rita Keynan
IPC分类号： A61K9/00 , A61K9/12 , A61K31/65 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/24 , A61K47/44 , A61K47/46
摘要： Provided are compositions and methods for treating rosacea and acne. Specifically, a gel or foam composition having a tetracycline antibiotic and uses thereof for treating rosacea and acne are provided.
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公开(公告)号：US11026920B2
公开(公告)日：2021-06-08
申请号：US16806752
申请日：2020-03-02
IPC分类号： A61K31/403 , A61K31/4035 , A61K9/06 , A61K47/10 , A61K9/20 , A61K9/48 , A61K9/00 , A61K45/06
摘要： The invention relates to methods for treating pruritus with NK-1 receptor antagonists such as serlopitant. The invention further relates to pharmaceutical compositions comprising NK-1 receptor antagonists such as serlopitant. In addition, the invention encompasses treatment of a pruritus-associated condition with serlopitant and an additional antipruritic agent, and the use of serlopitant as a sleep aid, optionally in combination with an additional sleep-aiding agent.
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公开(公告)号：US20230123488A1
公开(公告)日：2023-04-20
申请号：US16624244
申请日：2018-06-19
发明人： Yohan HAZOT , Tal BERMAN , Jana ZAILER , Orit AMSALEM , David SCHUZ , Anat LONDON-DRORI
摘要： Provided herein are compositions and methods for treating skin disorders, e.g., acne and/or rosacea. In some embodiments, the compositions may comprise carriers which are suitable for stabilizing an unstable active agent, e.g., a tetracycline antibiotic.
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公开(公告)号：US11103454B2
公开(公告)日：2021-08-31
申请号：US16445000
申请日：2019-06-18
发明人： Dov Tamarkin , Rita Keynan , David Schuz , Tal Berman
IPC分类号： A61K9/12 , A61Q19/08 , A61Q7/00 , A61Q5/00 , A61K8/04 , A61K8/86 , A61Q19/00 , A61K8/49 , A61K8/36 , A61K8/34 , A61K8/31 , A61K47/44 , A61K47/38 , A61K47/36 , A61K47/34 , A61K47/32 , A61K47/26 , A61K47/14 , A61K47/10 , A61Q19/02 , A61K9/00 , A61K9/107
摘要： Unique foamable vehicles or carriers comprising at least one wax, waxy substance, counterpart or derivative, a stabilizer, water, and a propellant are provided. In some embodiments, the wax is a liquid wax. In some embodiments, the wax includes a solid wax and a liquid wax. The compositions are substantially free of crystals. The components are selected to provide a composition that is substantially resistant to aging and to phase separation, and/or can substantially solubilize and or stabilize active ingredients. Pharmaceutical and cosmetic compositions with potentially enhanced skin delivery and their uses are also provided.
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公开(公告)号：US20230037905A1
公开(公告)日：2023-02-09
申请号：US17758175
申请日：2020-12-31
发明人： Russell ELLIOTT , Yohan HAZOT , Gareth WINCKLE , Ariel MARGULIS
IPC分类号： A61K31/519 , A61K31/137 , A61K47/14 , A61K9/00 , A61K47/44 , A61K9/107 , A61K9/12
摘要： The present disclosure relates to novel topical formulations containing a tofacitinib and or a fingolimod that are useful for treating dermatological conditions, such as atopic dermatitis, psoriasis, and eczema.
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公开(公告)号：US11324691B2
公开(公告)日：2022-05-10
申请号：US17075217
申请日：2020-10-20
发明人： Dov Tamarkin , Meir Eini , Yohan Hazot , Mitchell Shirvan , Tal Hetzroni Kedem , Rita Keynan
IPC分类号： A61K9/00 , A61K9/12 , A61K31/65 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/24 , A61K47/44 , A61K47/46
摘要： Provided are compositions and methods for treating rosacea and acne. Specifically, a gel or foam composition having a tetracycline antibiotic and uses thereof for treating rosacea and acne are provided.
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公开(公告)号：US20240325393A1
公开(公告)日：2024-10-03
申请号：US18041844
申请日：2021-07-07
发明人： Russell ELLIOTT , Yohan HAZOT , Gareth WINCKLE , Ariel MARGULIS
IPC分类号： A61K31/519 , A61K9/00 , A61K9/06 , A61K31/137 , A61K31/197 , A61K31/506 , A61K47/06 , A61K47/10 , A61K47/14 , A61K47/20 , A61K47/34 , A61K47/36 , A61K47/44
CPC分类号： A61K31/519 , A61K9/0014 , A61K9/06 , A61K31/137 , A61K31/197 , A61K31/506 , A61K47/06 , A61K47/10 , A61K47/14 , A61K47/20 , A61K47/34 , A61K47/36 , A61K47/44
摘要： The present disclosure relates to novel topical formulations containing a tofacitinib and or a fingolimod that are useful for treating dermatological conditions, such as atopic dermatitis, psoriasis, vitiligo and eczema.
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公开(公告)号：US20210169848A1
公开(公告)日：2021-06-10
申请号：US17263491
申请日：2019-07-26
发明人： Steven BASTA , Paul KWON
IPC分类号： A61K31/403 , A61P17/04 , A61K9/00
摘要： The disclosure relates to the use of neurokinin-1 (NK-1) antagonists in treating pruritus in a subject, wherein i) the duration of the pruritus is about one year or longer, ii) the subject is about 40 years of age or older: iii) the subject has no inflammatory skin disease; and/or iv) the pruritus is idiopathic.
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