Device and method for electrospinning multiple layered and three dimensional nanofibrous composite materials for tissue engineering

    公开(公告)号:US09803294B1

    公开(公告)日:2017-10-31

    申请号:US14098711

    申请日:2013-12-06

    IPC分类号: D01D5/00 A61L31/14

    CPC分类号: D01D5/0076 A61L2400/12

    摘要: The present invention relates to a device for preparing three dimensional (3D) nanofibers (blended or coaxial) materials by electrospinning. An automatic nanofiber collector device is used to control the porosity, pore size, crystallinity, geometry, the layer number and thickness of formed nanofibers. The automatic nanofiber collector device includes: (1) a collector platform; (2) a non-conductive device used to fix the collector device; (3) a plurality of electro-conductive wires or needles being pierced through the collector platform with various heights, and (4) the ends of the needles (at bottom) are wired and controlled by a microcontroller, providing forward, stand and backward movements for attached needles. The desired 3D nanofiber scaffold structures can be tailored by the micro-stepping programmable motor controller by changing the pattern and velocity of needle movement, generalized or selective needles movements, as well as intermittent versus continuous movement.

    Fingerstall-cannulated guide for fast and accurate guide wire positioning
    2.
    发明授权
    Fingerstall-cannulated guide for fast and accurate guide wire positioning 有权
    指管插管指南,用于快速准确的导丝定位

    公开(公告)号:US09549771B1

    公开(公告)日:2017-01-24

    申请号:US14092987

    申请日:2013-11-28

    摘要: The present invention provides a fingerstall-cannulated guide device for accurate and efficient guide wire placement for antegrade femoral nailing systems. The said device comprises a fingerstall with a cannulated guide connected with or without a threaded guide wire. Using this device, surgeons can determine the entry point for the guide wire fast and accurately by tactile hand-eye coordination. After correct entry point is obtained, the guide wire is advanced and the fingerstall-cannulated guide can be easily detached. The device and method can accomplish the following: (1) reduction of the surgery time; (2) reduction of the radiation exposure times, and (3) reduction of the soft tissue damage during surgery. The device is also beneficial for use in fastening together any or all portions of bone surrounding a fracture site.

    摘要翻译: 本发明提供了一种指状插管引导装置,用于准确和有效的导丝插入用于顺行股骨钉钉系统。 所述装置包括具有与或不带有螺纹导丝连接的插管引导件的指装置。 使用这种装置,外科医生可以通过触觉手眼协调快速准确地确定导丝的入口点。 在获得正确的入口点之后,引导线前进,并且指管插管引导件可以容易地分离。 该装置和方法可以完成以下工作:(1)减少手术时间; (2)减少辐射暴露时间,(3)手术中软组织损伤的减少。 该装置还有益于用于将骨折部位周围的骨骼的任何或所有部分紧固在一起。