-
公开(公告)号：US20050033055A1
公开(公告)日：2005-02-10
申请号：US10500895
申请日：2003-01-15
申请人： Robert Bugianesi , George Doherty , Amy Gentry , Jeffrey Hale , Christopher Lynch , Sander Mills , William Neway III
发明人： Robert Bugianesi , George Doherty , Amy Gentry , Jeffrey Hale , Christopher Lynch , Sander Mills , William Neway III
IPC分类号： A61K31/397 , A61K31/40 , A61K31/4025 , A61K31/41 , A61K31/4155 , A61K31/4245 , A61K31/675 , A61P1/02 , A61P1/04 , A61P1/16 , A61P3/10 , A61P5/14 , A61P7/06 , A61P9/00 , A61P9/04 , A61P9/10 , A61P11/00 , A61P11/02 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/04 , A61P17/06 , A61P17/14 , A61P19/02 , A61P19/10 , A61P21/00 , A61P21/04 , A61P25/00 , A61P25/06 , A61P27/02 , A61P27/12 , A61P29/00 , A61P31/14 , A61P31/20 , A61P35/00 , A61P35/04 , A61P37/02 , A61P37/06 , A61P37/08 , C07D205/04 , C07D207/16 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/10 , C07D413/14 , C07F9/572 , C07F9/6558 , C07F9/547 , C07D207/08 , C07D211/34
CPC分类号： C07D403/04 , C07D205/04 , C07D207/16 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/10 , C07D413/14 , C07F9/572 , C07F9/65586
摘要： The present invention encompasses compounds of Formula 1: as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.
摘要翻译： 本发明包括式1的化合物及其药学上可接受的盐和水合物。 该化合物可用于治疗免疫介导的疾病和病症，例如骨髓，器官和组织移植排斥反应。 包括药物组合物和使用方法。
-
2.发明申请3-(2-amino-1-azacyclyl)-5-aryl-1,2,4-oxadiazoles as s1p receptor agonists 审中-公开3-（2-氨基-1-氮杂环丙基）-5-芳基-1,2,4-恶二唑作为s1p受体激动剂公开(公告)号：US20060252741A1
公开(公告)日：2006-11-09
申请号：US10554665
申请日：2004-05-12
申请人： Vincent Colandrea , George Doherty , Jeffrey Hale , Christopher Lynch , Sander Mills , William Neway III , Leslie Toth
发明人： Vincent Colandrea , George Doherty , Jeffrey Hale , Christopher Lynch , Sander Mills , William Neway III , Leslie Toth
IPC分类号： A61K31/4439 , C07D413/04 , C07D413/14
CPC分类号： C07D413/04 , C07D271/06 , C07D413/14
摘要： The present invention encompasses compounds of Formula (I): as well as the pharmaceutically acceptable salts thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.
摘要翻译： 本发明包括式（I）的化合物及其药学上可接受的盐。 该化合物可用于治疗免疫介导的疾病和病症，例如骨髓，器官和组织移植排斥反应。 包括药物组合物和使用方法。
-
3.发明申请公开(公告)号：US20060089334A1
公开(公告)日：2006-04-27
申请号：US10505257
申请日：2003-02-27
申请人： Richard Budhu , George Doherty , Jeffrey Hale , Christopher Lynch , Sander Mills , William Neway
发明人： Richard Budhu , George Doherty , Jeffrey Hale , Christopher Lynch , Sander Mills , William Neway
IPC分类号： A61K31/433 , A61K31/426 , A61K31/4245 , A61K31/421 , A61K31/4172 , A61K31/4152
CPC分类号： C07D257/04 , C07C229/34 , C07C309/24 , C07C311/51 , C07D233/84 , C07D249/04 , C07D249/12 , C07D257/06 , C07F9/094 , C07F9/3808 , C07F9/3826 , C07F9/3882
摘要： The present invention encompasses compounds or Formula (I): as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.
摘要翻译： 本发明包括化合物或式（I）：及其药学上可接受的盐和水合物。 该化合物可用于治疗免疫介导的疾病和病症，例如骨髓，器官和组织移植排斥反应。 包括药物组合物和使用方法。
-
4.发明申请1-((5-aryl-1,2,4-oxadiazol-3-yl) benzyl)azetidine-3-carboxylates and 1-((5-aryl-1,2,4-oxadiazol-3-yl)benzyl) pyrrolidine-3-carboxylates as edg receptor agonists 失效1 - （（5-芳基-1,2,4-恶二唑-3-基）苄基）氮杂环丁烷-3-羧酸酯和1 - （（5-芳基-1,2,4-恶二唑-3-基）苄基） 吡咯烷-3-羧酸盐作为edg受体激动剂公开(公告)号：US20050245575A1
公开(公告)日：2005-11-03
申请号：US10515192
申请日：2003-06-16
申请人： Weirong Chen , Jeffrey Hale , Zhen Li , Christopher Lynch , Sander Mills , William Neway
发明人： Weirong Chen , Jeffrey Hale , Zhen Li , Christopher Lynch , Sander Mills , William Neway
IPC分类号： A61K31/4245 , A61K31/454 , A61P1/02 , A61P1/04 , A61P1/16 , A61P1/18 , A61P3/10 , A61P7/06 , A61P9/10 , A61P11/00 , A61P11/02 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/06 , A61P17/14 , A61P19/02 , A61P21/00 , A61P21/04 , A61P25/00 , A61P25/06 , A61P25/28 , A61P27/02 , A61P27/12 , A61P29/00 , A61P31/00 , A61P31/04 , A61P31/12 , A61P31/18 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/06 , A61P37/08 , A61P43/00 , C07D413/02 , C07D413/10 , C07D413/14
CPC分类号： C07D413/10 , A61K31/4245 , C07D413/14
摘要： The present invention encompasses compounds of Formula I: as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.
摘要翻译： 本发明包括式I的化合物以及其药学上可接受的盐和水合物。 该化合物可用于治疗免疫介导的疾病和病症，例如骨髓，器官和组织移植排斥反应。 包括药物组合物和使用方法。
-
-
-
搜索结果
4 条记录 (耗时 0.018 秒)
