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1.发明授权Method for irradiating thrombocyte concentrates in flexible containers with ultra-violet light 有权用紫外光照射柔性容器中的血细胞浓缩物的方法公开(公告)号：US08173066B2
公开(公告)日：2012-05-08
申请号：US12086806
申请日：2006-12-21
申请人： Harald Mohr , Wolfram H. Walker
发明人： Harald Mohr , Wolfram H. Walker
CPC分类号： A61L2/0011 , A61L2/10
摘要： The invention relates to a method for inactivating pathogens such as bacteria and viruses and/or leucocytes in thrombocyte concentrations by irradiation in flexible containers with ultra-violet light using agitation. The blood product is packaged in a flexible bag to permit the intermixing of the fluid by agitation (tilting, rotation, translation). This is also promoted by the filling of the bag to a maximum 30% of the filling capacity.
摘要翻译： 本发明涉及通过使用搅动用紫外光照射在柔性容器中灭活细胞和病毒和/或白细胞的细胞和/或白细胞的方法。 血液产品被包装在柔性袋中，以允许通过搅动（倾斜，旋转，平移）混合流体。 这也通过将袋子的填充量提高到填充能力的最大30％来促进。
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2.发明申请Method for Irradiating Thrombocyte Concentrates in Flexible Containers With Ultra-Violet Light 有权用超紫外光照射柔性容器中的血细胞浓缩物的方法公开(公告)号：US20090155121A1
公开(公告)日：2009-06-18
申请号：US12086806
申请日：2006-12-21
申请人： Harald Mohr , Wolfram H. Walker
发明人： Harald Mohr , Wolfram H. Walker
IPC分类号： A61L2/00
CPC分类号： A61L2/0011 , A61L2/10
摘要： The invention relates to a method for inactivating pathogens such as bacteria and viruses and/or leucocytes in thrombocyte concentrations by irradiation in flexible containers with ultra-violet light using agitation. The blood product is packaged in a flexible bag to permit the intermixing of the fluid by agitation (tilting, rotation, translation). This is also promoted by the filling of the bag to a maximum 30% of the filling capacity.
摘要翻译： 本发明涉及通过使用搅动用紫外光照射在柔性容器中灭活细胞和病毒和/或白细胞的细胞和/或白细胞的方法。 血液产品被包装在柔性袋中，以允许通过搅动（倾斜，旋转，平移）混合流体。 这也通过将袋子的填充量提高到填充能力的最大30％来促进。
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3.发明授权
公开(公告)号：US4572899A
公开(公告)日：1986-02-25
申请号：US511434
申请日：1983-07-06
CPC分类号： A01N1/0226 , A01N1/02 , A61K35/18 , Y10T436/106664 , Y10T436/107497 , Y10T436/108331
摘要： An aqueous solution for suspending and storing cells, especially erythrocytes, and containing sodium chloride, glucose or fructose, adenine, and a sugar alcohol, the sugar alcohol being sorbitol or xylitol is employed to further improve the storage time and hence the survival rate of the cells and even reduce the hemolysis rate of erythrocytes in packed red blood cells.
摘要翻译： 用于悬浮和储存细胞，特别是红细胞并含有氯化钠，葡萄糖或果糖，腺嘌呤和糖醇的水溶液，糖醇是山梨糖醇或木糖醇用于进一步改善储存时间，从而进一步改善存活时间 细胞甚至降低红细胞中红细胞的溶血率。
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公开(公告)号：US4460365A
公开(公告)日：1984-07-17
申请号：US80622
申请日：1979-10-01
CPC分类号： A61J1/10 , Y10S128/24
摘要： A bag suitable for the storage, deep-freezing and transfusion of blood and blood components formed of a calendered or extruded foil of plasticizer-free polyurethane of a thickness of about 0.1-0.5 mm, a Shore hardness A of about 60-85, temperature resistance up to about 160.degree. C. and down to about -196.degree. C. without change of properties. The bag can be used in combination with fittings and tubings of the same material to provide an overall plasticizer-free polyurethane system. The bag can be sterilized, is capable of low temperature storage, and exhibits other desirable properties without affecting the quality of its contents.
摘要翻译： 一种适用于储存，深度冷冻和输血的血液和血液成分，其由厚度约0.1-0.5mm的砑光或挤出的不含增塑剂的聚氨酯薄片形成，肖氏硬度A为约60-85，温度 电阻高达约160℃，低至约-196℃，而不改变性能。 该袋可以与相同材料的配件和管道组合使用，以提供总体无增塑剂的聚氨酯体系。 该袋可以灭菌，能够低温储存，并且表现出其它所需的性能，而不影响其内容物的质量。
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5.发明授权Microfiltration device for the filtration of coagula and microaggregates from blood 失效用于从血液过滤凝血酶和微团聚体的微过滤装置
公开(公告)号：US4450078A
公开(公告)日：1984-05-22
申请号：US427234
申请日：1982-09-29
CPC分类号： A61M5/165
摘要： A microfiltration device for the filtration of coagula and microaggregates from blood and blood components. The device contains a filter chamber with attaching nozzle, a filter cone containing truncoconical filter elements arranged in cascade with diminishing pore size and diminishing surface area, a drip chamber and a tailpiece. The filter chamber and filter cones have different tapers and are at a specific distance apart, the taper of the filter cone from inlet to outlet being greater than the taper of the filter chamber. The filter cone has up to four filter elements, and a spacer which extends into the filter element of smallest pore size and surface area and supports same. Each of the filter elements has at least two opposed ribs running from the base to the apex of the truncated cone. The spacer is constructed such that it serves simultaneously for the support of the ribs and for the support of the filter fabric of the smallest filter element. The device has a capacity of less than 100 ml. It is intended for use in transfusions of preserved blood or blood components, especially massive transfusions.
摘要翻译： 用于从血液和血液成分过滤凝结物和微团聚体的微量过滤装置。 该装置包括具有连接喷嘴的过滤室，包含与孔径减小和表面积减小成一列排列的截面过滤元件的过滤器锥体，滴注室和尾件。 过滤室和过滤器锥体具有不同的锥度并且在特定的距离处，过滤器锥体从入口到出口的锥度大于过滤室的锥度。 过滤锥体具有多达四个过滤元件，以及间隔物，其延伸到具有最小孔径和表面积的过滤元件中并且支撑相同的。 每个过滤元件具有至少两个相对的肋，从基部到截锥的顶点延伸。 间隔件被构造成使得其同时用于肋的支撑和用于支撑最小过滤元件的过滤织物。 该装置的容量小于100毫升。 它用于输血保存的血液或血液成分，特别是大量输血。
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公开(公告)号：US4435179A
公开(公告)日：1984-03-06
申请号：US319769
申请日：1981-11-09
申请人： Wolfram H. Walker
发明人： Wolfram H. Walker
CPC分类号： A61J1/10
摘要： In a blood bag assembly comprising a blood bag and means for connecting the interior of the bag with the interior of a second bag, the improvement wherein said connecting means comprises a coupling composed of a connecting portion, a break-off portion, and a break-off point, the coupling being joined directly at the upper edge of the bag and terminates substantially evenly therewith, the break-off portion will be inside of the bag after it is broken off.
摘要翻译： 在包括血袋的血袋组件和用于将袋的内部与第二袋的内部连接的装置的改进之处在于，所述连接装置包括由连接部分，断裂部分和断裂部分组成的联接 离合点直接连接在袋的上边缘处并大致均匀地终止，分离部分在其被分解之后将在袋的内部。
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