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公开(公告)号:US20100249133A1
公开(公告)日:2010-09-30
申请号:US12772951
申请日:2010-05-03
申请人: Milan Bruncko , Hong Ding , Steven W. Elmore , Aaron R. Kunzer , Christopher L. Lynch , William J. McClellan , Cheol Min Park , Xiahong Song , Xilu Wang
发明人: Milan Bruncko , Hong Ding , Steven W. Elmore , Aaron R. Kunzer , Christopher L. Lynch , William J. McClellan , Cheol Min Park , Xiahong Song , Xilu Wang
IPC分类号: A61K31/496 , A61K31/4965 , A61K31/5377
CPC分类号: C07D295/155 , C07D487/08 , C07D491/08
摘要: Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti-apoptotic family protein member are disclosed.
摘要翻译: 公开了抑制抗凋亡家族蛋白成员的活性的化合物,含有该化合物的组合物和治疗疾病的方法,其中表达一种或多种抗凋亡家族蛋白质成员。
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公开(公告)号:US20080287419A1
公开(公告)日:2008-11-20
申请号:US12120914
申请日:2008-05-15
申请人: Milan Bruncko , Hong Ding , Steven W. Elmore , Aaron R. Kunzer , Christopher L. Lynch , William J. McClellan , Cheol Min Park , Xiahong Song , Xilu Wang
发明人: Milan Bruncko , Hong Ding , Steven W. Elmore , Aaron R. Kunzer , Christopher L. Lynch , William J. McClellan , Cheol Min Park , Xiahong Song , Xilu Wang
IPC分类号: A61K31/553 , C07D413/02 , A61K31/5377 , C07D223/02 , A61K31/496 , A61P35/00 , C07D295/00 , A61K31/55 , C07D267/02
CPC分类号: C07D295/155 , C07D487/08 , C07D491/08
摘要: Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti-apoptotic family protein member are disclosed.
摘要翻译: 公开了抑制抗凋亡家族蛋白成员的活性的化合物,含有该化合物的组合物和治疗疾病的方法,其中表达一种或多种抗凋亡家族蛋白质成员。
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公开(公告)号:US07906505B2
公开(公告)日:2011-03-15
申请号:US12772951
申请日:2010-05-03
申请人: Milan Bruncko , Hong Ding , Steven W. Elmore , Aaron R. Kunzer , Christopher L. Lynch , William J. McClellan , Cheol Min Park , Xiahong Song , Xilu Wang
发明人: Milan Bruncko , Hong Ding , Steven W. Elmore , Aaron R. Kunzer , Christopher L. Lynch , William J. McClellan , Cheol Min Park , Xiahong Song , Xilu Wang
IPC分类号: C07D413/02 , C07D403/02 , A61K31/553 , A61K31/55 , A61K31/5377
CPC分类号: C07D295/155 , C07D487/08 , C07D491/08
摘要: Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti-apoptotic family protein member are disclosed.
摘要翻译: 公开了抑制抗凋亡家族蛋白成员的活性的化合物,含有该化合物的组合物和治疗疾病的方法,其中表达一种或多种抗凋亡家族蛋白质成员。
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公开(公告)号:US07709467B2
公开(公告)日:2010-05-04
申请号:US12120914
申请日:2008-05-15
申请人: Milan Bruncko , Hong Ding , Steven W. Elmore , Aaron R. Kunzer , Christopher L. Lynch , William J. McClellan , Cheol Min Park , Xiahong Song , Xilu Wang
发明人: Milan Bruncko , Hong Ding , Steven W. Elmore , Aaron R. Kunzer , Christopher L. Lynch , William J. McClellan , Cheol Min Park , Xiahong Song , Xilu Wang
IPC分类号: C07D241/04 , A61K31/496
CPC分类号: C07D295/155 , C07D487/08 , C07D491/08
摘要: Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti-apoptotic family protein member are disclosed.
摘要翻译: 公开了抑制抗凋亡家族蛋白成员的活性的化合物,含有该化合物的组合物和治疗疾病的方法,其中表达一种或多种抗凋亡家族蛋白质成员。
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公开(公告)号:US07390799B2
公开(公告)日:2008-06-24
申请号:US11432937
申请日:2006-05-12
申请人: Milan Bruncko , Hong Ding , Steven W. Elmore , Aaron R. Kunzer , Christopher L. Lynch , William J. McClellan , Cheol Min Park , Xiahong Song , Xilu Wang
发明人: Milan Bruncko , Hong Ding , Steven W. Elmore , Aaron R. Kunzer , Christopher L. Lynch , William J. McClellan , Cheol Min Park , Xiahong Song , Xilu Wang
IPC分类号: C07D413/02 , C07D403/02 , A61K31/553 , A61K31/55 , A61K31/5377 , A61K31/496
CPC分类号: C07D295/155 , C07D487/08 , C07D491/08
摘要: Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti-apoptotic family protein member are disclosed.
摘要翻译: 公开了抑制抗凋亡家族蛋白成员的活性的化合物,含有该化合物的组合物和治疗疾病的方法,其中表达一种或多种抗凋亡家族蛋白质成员。
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公开(公告)号:US20070027135A1
公开(公告)日:2007-02-01
申请号:US11432937
申请日:2006-05-12
申请人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher Lynch , William McClellan , Cheol Park , Xiahong Song , Xilu Wang
发明人: Milan Bruncko , Hong Ding , Steven Elmore , Aaron Kunzer , Christopher Lynch , William McClellan , Cheol Park , Xiahong Song , Xilu Wang
IPC分类号: A61K31/553 , A61K31/55 , A61K31/5377 , A61K31/496 , C07D413/02 , C07D403/02
CPC分类号: C07D295/155 , C07D487/08 , C07D491/08
摘要: Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti-apoptotic family protein member are disclosed.
摘要翻译: 公开了抑制抗凋亡家族蛋白成员的活性的化合物,含有该化合物的组合物和治疗疾病的方法,其中表达一种或多种抗凋亡家族蛋白质成员。
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