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公开(公告)号：US08575321B2
公开(公告)日：2013-11-05
申请号：US13333295
申请日：2011-12-21
申请人： Yuanwei Chen , Huawei Cheng , Shengbin Li , Yuelin Wu , Yan Feng , Binhua Lv , Baihua Xu , Brian Seed , Michael Hadd , Yanli Song , Jiyan Du , Congna Wang , Jacques Roberge
发明人： Yuanwei Chen , Huawei Cheng , Shengbin Li , Yuelin Wu , Yan Feng , Binhua Lv , Baihua Xu , Brian Seed , Michael Hadd , Yanli Song , Jiyan Du , Congna Wang , Jacques Roberge
IPC分类号： C07H1/00
CPC分类号： C07H7/04 , C07D309/10 , C07D407/12
摘要： Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
摘要翻译： 提供对钠依赖性葡萄糖转运蛋白SGLT具有抑制作用的化合物。 本发明还提供药物组合物，制备化合物的方法，合成中间体，以及独立地或与其它治疗剂组合使用化合物治疗受SGLT抑制影响的疾病和病症的方法。
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公开(公告)号：US20120329732A1
公开(公告)日：2012-12-27
申请号：US13333295
申请日：2011-12-21
申请人： Yuanwei Chen , Huawei Cheng , Shengbin Li , Yuelin Wu , Yan Feng , Binhua Lv , Baihua Xu , Brian Seed , Michael J. Hadd , Yanli Song , Jiyan Du , Congna Wang , Jacques Y. Roberge
发明人： Yuanwei Chen , Huawei Cheng , Shengbin Li , Yuelin Wu , Yan Feng , Binhua Lv , Baihua Xu , Brian Seed , Michael J. Hadd , Yanli Song , Jiyan Du , Congna Wang , Jacques Y. Roberge
IPC分类号： A61K31/706 , C07H15/207 , A61P3/10 , C07H15/26
CPC分类号： C07H7/04 , C07D309/10 , C07D407/12
摘要： Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
摘要翻译： 提供对钠依赖性葡萄糖转运蛋白SGLT具有抑制作用的化合物。 本发明还提供药物组合物，制备化合物的方法，合成中间体，以及独立地或与其它治疗剂组合使用化合物治疗受SGLT抑制影响的疾病和病症的方法。
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公开(公告)号：US20110207661A1
公开(公告)日：2011-08-25
申请号：US12917367
申请日：2010-11-01
申请人： Yuanwei Chen , Huawei Cheng , Shengbin Li , Yuelin Wu , Yan Feng , Binhua Lv , Baihua Xu , Brian Seed , Michael J. Hadd , Yanli Song , Jiyan Du , Congna Wang , Jacques Y. Roberge
发明人： Yuanwei Chen , Huawei Cheng , Shengbin Li , Yuelin Wu , Yan Feng , Binhua Lv , Baihua Xu , Brian Seed , Michael J. Hadd , Yanli Song , Jiyan Du , Congna Wang , Jacques Y. Roberge
CPC分类号： C07H7/04 , C07D309/10 , C07D407/12
摘要： Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
摘要翻译： 提供对钠依赖性葡萄糖转运蛋白SGLT具有抑制作用的化合物。 本发明还提供药物组合物，制备化合物的方法，合成中间体，以及独立地或与其它治疗剂组合使用化合物治疗受SGLT抑制影响的疾病和病症的方法。
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公开(公告)号：US08106021B2
公开(公告)日：2012-01-31
申请号：US12917367
申请日：2010-11-01
申请人： Yuanwei Chen , Huawei Cheng , Shengbin Li , Yuelin Wu , Yan Feng , Binhua Lv , Baihua Xu , Brian Seed , Michael J. Hadd , Yanli Song , Jiyan Du , Congna Wang , Jacques Y. Roberge
发明人： Yuanwei Chen , Huawei Cheng , Shengbin Li , Yuelin Wu , Yan Feng , Binhua Lv , Baihua Xu , Brian Seed , Michael J. Hadd , Yanli Song , Jiyan Du , Congna Wang , Jacques Y. Roberge
CPC分类号： C07H7/04 , C07D309/10 , C07D407/12
摘要： Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
摘要翻译： 提供对钠依赖性葡萄糖转运蛋白SGLT具有抑制作用的化合物。 本发明还提供药物组合物，制备化合物的方法，合成中间体，以及独立地或与其它治疗剂组合使用化合物治疗受SGLT抑制影响的疾病和病症的方法。
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公开(公告)号：US07838499B2
公开(公告)日：2010-11-23
申请号：US12197095
申请日：2008-08-22
申请人： Yuanwei Chen , Huawei Cheng , Shengbin Li , Yuelin Wu , Yan Feng , Binhua Lv , Baihua Xu , Brian Seed , Michael J. Hadd , Yanli Song , Jiyan Du , Congna Wang , Jacques Y. Roberge
发明人： Yuanwei Chen , Huawei Cheng , Shengbin Li , Yuelin Wu , Yan Feng , Binhua Lv , Baihua Xu , Brian Seed , Michael J. Hadd , Yanli Song , Jiyan Du , Congna Wang , Jacques Y. Roberge
CPC分类号： C07H7/04 , C07D309/10 , C07D407/12
摘要： Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
摘要翻译： 提供对钠依赖性葡萄糖转运蛋白SGLT具有抑制作用的化合物。 本发明还提供药物组合物，制备化合物的方法，合成中间体，以及独立地或与其它治疗剂组合使用化合物治疗受SGLT抑制影响的疾病和病症的方法。
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公开(公告)号：US08975418B2
公开(公告)日：2015-03-10
申请号：US14013097
申请日：2013-08-29
申请人： Wenjian Shi , Yanli Song , Yuhui Bao , Jun Lu , Yao Huang , Dirk Weber
发明人： Wenjian Shi , Yanli Song , Yuhui Bao , Jun Lu , Yao Huang , Dirk Weber
IPC分类号： C07C69/78 , C07D209/12 , C07D209/36 , C07D209/34 , C07C207/04 , C07C201/12 , C07D209/42 , C07C205/56
CPC分类号： C07D209/34 , C07C69/78 , C07C201/12 , C07C205/56 , C07C207/04 , C07D209/12 , C07D209/42 , C07C205/12
摘要： Disclosed is a method for the synthesis of 6-iodo-2-oxindole useful as intermediate in the manufacture of pharmaceutically active ingredients. Also disclosed is a novel intermediate used in the synthesis of this compound.
摘要翻译： 公开了用作合成制备药物活性成分的6-碘-2-羟基吲哚的方法。 还公开了用于合成该化合物的新型中间体。
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公开(公告)号：US20140066634A1
公开(公告)日：2014-03-06
申请号：US14013097
申请日：2013-08-29
申请人： Wenjian SHI , Yanli Song , Yuhui Bao , Jun Lu , Yao Huang , Dirk Weber
发明人： Wenjian SHI , Yanli Song , Yuhui Bao , Jun Lu , Yao Huang , Dirk Weber
IPC分类号： C07D209/34 , C07C201/12 , C07D209/42 , C07C207/04
CPC分类号： C07D209/34 , C07C69/78 , C07C201/12 , C07C205/56 , C07C207/04 , C07D209/12 , C07D209/42 , C07C205/12
摘要： Disclosed is a method for the synthesis of 6-iodo-2-oxindole useful as intermediate in the manufacture of pharmaceutically active ingredients. Also disclosed is a novel intermediate used in the synthesis of this compound.
摘要翻译： 公开了用作合成制备药物活性成分的6-碘-2-羟基吲哚的方法。 还公开了用于合成该化合物的新型中间体。
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公开(公告)号：USD1030567S1
公开(公告)日：2024-06-11
申请号：US29933660
申请日：2024-03-21
申请人： Yanli Song
设计人： Yanli Song
摘要： FIG. 1 is a top perspective view of a trailer lock showing my new design;
FIG. 2 is a front view thereof;
FIG. 3 is a rear view thereof;
FIG. 4 is a left side view thereof;
FIG. 5 is a right side view thereof;
FIG. 6 is a top plan view thereof; and,
FIG. 7 is a bottom plan view thereof.
The broken lines in the drawings depict portions of the trailer lock that form no part of the claimed design.-
公开(公告)号：US20090118201A1
公开(公告)日：2009-05-07
申请号：US12197095
申请日：2008-08-22
申请人： Yuanwei Chen , Huawei Cheng , Shengbin Li , Yuelin Wu , Yan Feng , Binhua Lv , Baihua Xu , Brian Seed , Michael J. Hadd , Yanli Song , Jiyan Du , Congna Wang , Jacques Y. Roberge
发明人： Yuanwei Chen , Huawei Cheng , Shengbin Li , Yuelin Wu , Yan Feng , Binhua Lv , Baihua Xu , Brian Seed , Michael J. Hadd , Yanli Song , Jiyan Du , Congna Wang , Jacques Y. Roberge
IPC分类号： A61K31/7028 , C07H7/04 , C07H7/06 , A61P3/10
CPC分类号： C07H7/04 , C07D309/10 , C07D407/12
摘要： Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
摘要翻译： 提供对钠依赖性葡萄糖转运蛋白SGLT具有抑制作用的化合物。 本发明还提供药物组合物，制备化合物的方法，合成中间体，以及独立地或与其它治疗剂组合使用化合物治疗受SGLT抑制影响的疾病和病症的方法。
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