公开(公告)号：US20250075272A1

公开(公告)日：2025-03-06

申请号：US18951533

申请日：2024-11-18

Applicant: 10x Genomics, Inc.

Inventor： Solongo B. ZIRALDO ,  Geoffrey MCDERMOTT ,  Shea Thompson LANCE

IPC: C12Q1/6883 ,  C12Q1/6827 ,  G16B30/00 ,  G16B30/10 ,  G16B30/20

Abstract: The present disclosure relates to methods, compositions and systems for haplotype phasing and copy number variation assays. Included within this disclosure are methods and systems for combining the barcode comprising beads with samples in multiple separate partitions, as well as methods of processing, sequencing and analyzing barcoded samples.

公开(公告)号：US20230304072A1

公开(公告)日：2023-09-28

申请号：US18187981

申请日：2023-03-22

Applicant: 10x Genomics, Inc.

Inventor： Shalini GOHIL ,  Shea Thompson LANCE ,  Geoffrey P. MCDERMOTT ,  David Michael PATTERSON ,  Andrew D. PRICE

IPC: C12Q1/6806 ,  C12N15/10 ,  C08J3/075 ,  B01J13/02

CPC classification number: C12Q1/6806 ,  B01J13/02 ,  C08J3/075 ,  C12N15/1082 ,  C08J2333/26

Abstract: The present disclosure relates generally to compositions and methods for generating hydrogel coatings on features. In some embodiments, hydrogel-coated features are prepared by horseradish peroxidase-mediated gelation of microspheres. Some embodiments relate to methods for generating hydrogel coatings using particle templated emulsification. The disclosure also relates to the use of hydrogel-coated features in arrays for spatial analysis of biological analytes in biological samples.