公开(公告)号：US20150004682A1

公开(公告)日：2015-01-01

申请号：US14488332

申请日：2014-09-17

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jeffrey D. Smith ,  Jeffrey C. Pederson ,  Sailaja Chandrapati ,  RuthAnn R. Duda

IPC: C12Q1/22

CPC classification number: C12Q1/22

Abstract: A biological sterilization indicator (BI) and method of using same. The BI can include a housing, and a container positioned in the housing. The container can contain a liquid and at least a portion of the container can be frangible. The BI can further include a first chamber and a second chamber. The second chamber can include at least one source of biological activity. The BI can further include a first fluid path positioned to fluidly couple the first chamber and the second chamber, and a second fluid path positioned to allow displaced gas to move out of the second chamber. The method can include moving displaced gas out of the second chamber via the second fluid path as a sterilant is moved into the second chamber via the first fluid path and/or as the liquid is moved into the second chamber via the first fluid path.

Abstract translation: 生物灭菌指示剂（BI）及其使用方法。 BI可以包括壳体和位于壳体中的容器。 容器可以容纳液体，容器的至少一部分可以是易碎的。 BI还可以包括第一室和第二室。 第二室可以包括至少一种生物活性来源。 BI还可以包括定位成流体耦合第一室和第二室的第一流体路径，以及定位成允许排出的气体移出第二室的第二流体路径。 该方法可以包括当消毒剂经由第一流体路径移动到第二室中时和/或当液体经由第一流体路径移动到第二室中时，通过第二流体路径将移动的气体移出第二室。

公开(公告)号：US10287618B2

公开(公告)日：2019-05-14

申请号：US15129442

申请日：2015-03-24

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Francois Ahimou ,  RuthAnn R. Duda ,  G. Marco Bommarito ,  Timothy J. Nies ,  Kai Qiu

IPC: C12Q1/22 ,  A61L2/28 ,  A61L2/04 ,  A61B90/70 ,  A61L2/18

Abstract: A composition for monitoring the efficacy of a decontamination process is provided, the composition comprising a cellulose polymer and a predetermined quantity of an adenine nucleotide. A monitoring device comprising a test element with the composition disposed thereon is also provided. The composition and/or monitoring device can be used in a method. The method includes exposing the monitoring device to a decontamination process and subsequently measuring the residual tracer analyte on the monitoring device.

公开(公告)号：US10047334B2

公开(公告)日：2018-08-14

申请号：US15064918

申请日：2016-03-09

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Sailaja Chandrapati ,  Heather M. Webb ,  Jeffrey C. Pederson ,  Jeffrey D. Smith ,  RuthAnn R. Duda ,  Brian J. Engel

IPC: B01L3/00 ,  C12M3/00 ,  C12M1/12 ,  C12Q1/22 ,  G01N21/64 ,  C12Q1/04 ,  C12M1/00

CPC classification number: C12M37/06 ,  C12M23/32 ,  C12M25/06 ,  C12Q1/04 ,  C12Q1/22 ,  G01N21/6486

Abstract: A biological sterilization indicator (BI). The BI can include a housing, and a container positioned in the housing. The container can contain a liquid and at least a portion of the container can be frangible. The BI can further include a first chamber and a second chamber. The second chamber can include at least one source of biological activity. The BI can further include a substrate positioned in the housing between the first chamber and the second chamber. The substrate can be positioned in fluid communication with the first chamber and the second chamber, and the substrate can be further positioned such that the substrate is not in direct contact with the source of biological activity.

公开(公告)号：US09540677B2

公开(公告)日：2017-01-10

申请号：US14488332

申请日：2014-09-17

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jeffrey D. Smith ,  Jeffrey C. Pederson ,  Sailaja Chandrapati ,  RuthAnn R. Duda

IPC: C12M1/00 ,  B01L3/00 ,  C12Q1/22

CPC classification number: C12Q1/22

Abstract: A biological sterilization indicator (BI) and method of using same. The BI can include a housing, and a container positioned in the housing. The container can contain a liquid and at least a portion of the container can be frangible. The BI can further include a first chamber and a second chamber. The second chamber can include at least one source of biological activity. The BI can further include a first fluid path positioned to fluidly couple the first chamber and the second chamber, and a second fluid path positioned to allow displaced gas to move out of the second chamber. The method can include moving displaced gas out of the second chamber via the second fluid path as a sterilant is moved into the second chamber via the first fluid path and/or as the liquid is moved into the second chamber via the first fluid path.

Abstract translation: 生物灭菌指示剂（BI）及其使用方法。 BI可以包括壳体和位于壳体中的容器。 容器可以容纳液体，容器的至少一部分可以是易碎的。 BI还可以包括第一室和第二室。 第二室可以包括至少一种生物活性来源。 BI还可以包括定位成流体耦合第一室和第二室的第一流体路径，以及定位成允许排出的气体移出第二室的第二流体路径。 该方法可以包括当消毒剂经由第一流体路径移动到第二室中时和/或当液体经由第一流体路径移动到第二室中时，通过第二流体路径将移动的气体移出第二室。

公开(公告)号：US20160186120A1

公开(公告)日：2016-06-30

申请号：US15064918

申请日：2016-03-09

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Sailaja Chandrapati ,  Heather M. Webb ,  Jeffrey C. Pederson ,  Jeffrey D. Smith ,  RuthAnn R. Duda ,  Brian J. Engel

IPC: C12M1/12 ,  C12M1/00

CPC classification number: C12M37/06 ,  C12M23/32 ,  C12M25/06 ,  C12Q1/04 ,  C12Q1/22 ,  G01N21/6486

Abstract: A biological sterilization indicator (BI). The BI can include a housing, and a container positioned in the housing. The container can contain a liquid and at least a portion of the container can be frangible. The BI can further include a first chamber and a second chamber. The second chamber can include at least one source of biological activity. The BI can further include a substrate positioned in the housing between the first chamber and the second chamber. The substrate can be positioned in fluid communication with the first chamber and the second chamber, and the substrate can be further positioned such that the substrate is not in direct contact with the source of biological activity.