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公开(公告)号：US10947577B2
公开(公告)日：2021-03-16
申请号：US14377203
申请日：2013-02-11
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Francois Ahimou , Sailaja Chandrapati , Kurt J. Halverson , Heather M. Webb , Michael G. Williams
Abstract: A biological sterilization indicator device is provided. The device comprises a body, a plurality of test microorganisms, and an oxygen-modulated first fluorescent sensor. The body comprises a first layer attached to a second layer, forming at least one isolatable microchamber and at least one primary passageway that provides fluidic communication between ambience and the at least one microchamber. The microchamber has an isolated volume of about 0.5 microliters to about 9.5 microliters. The plurality of test microorganisms and the oxygen-modulated first fluorescent sensor are disposed in the microchamber. A method of using the device to determine the effectiveness of a sterilization process is also provided.
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公开(公告)号：US20160186120A1
公开(公告)日：2016-06-30
申请号：US15064918
申请日：2016-03-09
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Sailaja Chandrapati , Heather M. Webb , Jeffrey C. Pederson , Jeffrey D. Smith , RuthAnn R. Duda , Brian J. Engel
Abstract: A biological sterilization indicator (BI). The BI can include a housing, and a container positioned in the housing. The container can contain a liquid and at least a portion of the container can be frangible. The BI can further include a first chamber and a second chamber. The second chamber can include at least one source of biological activity. The BI can further include a substrate positioned in the housing between the first chamber and the second chamber. The substrate can be positioned in fluid communication with the first chamber and the second chamber, and the substrate can be further positioned such that the substrate is not in direct contact with the source of biological activity.
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公开(公告)号：US10047334B2
公开(公告)日：2018-08-14
申请号：US15064918
申请日：2016-03-09
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Sailaja Chandrapati , Heather M. Webb , Jeffrey C. Pederson , Jeffrey D. Smith , RuthAnn R. Duda , Brian J. Engel
Abstract: A biological sterilization indicator (BI). The BI can include a housing, and a container positioned in the housing. The container can contain a liquid and at least a portion of the container can be frangible. The BI can further include a first chamber and a second chamber. The second chamber can include at least one source of biological activity. The BI can further include a substrate positioned in the housing between the first chamber and the second chamber. The substrate can be positioned in fluid communication with the first chamber and the second chamber, and the substrate can be further positioned such that the substrate is not in direct contact with the source of biological activity.
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Patent Agency Ranking
公开(公告)号：US20150165082A1
公开(公告)日：2015-06-18
申请号：US14625176
申请日：2015-02-18
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Sailaja Chandrapati , Jeffrey C. Pederson , Heather M. Webb , Jeffrey D. Smith , Kurt J. Halverson , Bryan S. Behun , Peter D. Ludowise
Abstract: A biological sterilization indicator, system, and methods of determining the effectiveness of a sterilization process. The biological sterilization indicator can include a locus of spores, a reservoir containing a liquid, and a sterilant path positioned to provide fluid communication between ambience and the locus of spores. The reservoir can have a closed state in which the reservoir is not in fluid communication with the locus of spores and an open state in which the reservoir is in fluid communication with the locus of spores. The biological sterilization indicator system can include the biological sterilization indicator and a detection device adapted to be coupled to the biological sterilization indicator. In some embodiments, the method can include assaying the spores for a detectable change in a characteristic, and detecting substantially all of the detectable change.
Abstract translation: 一种生物灭菌指标，系统和确定灭菌过程有效性的方法。 生物灭菌指示剂可以包括孢子的位点，含有液体的储存器和定位成在气氛和孢子的位置之间提供流体连通的消毒剂通道。 储存器可以具有闭合状态，其中储存器不与孢子的轨迹流体连通，并且储存器与孢子的轨迹流体连通的打开状态。 生物灭菌指示器系统可以包括生物灭菌指示器和适于联接到生物灭菌指示器的检测装置。 在一些实施方案中，该方法可以包括测定孢子以获得特征的可检测变化，并且检测基本上所有可检测的变化。
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公开(公告)号：US20130168441A1
公开(公告)日：2013-07-04
申请号：US13681056
申请日：2012-11-19
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Kevin D. Landgrebe , Heather M. Webb , Bernard A. Gonzalez , Timothy J. Nies , Peter J. Molitor , Patricia S. Columbus-Powers , Michael J. Fletcher
CPC classification number: B65D25/14 , B31B2120/40 , B65D7/26 , B65D11/1833 , B65D25/16 , B65D75/14
Abstract: A foldable shell having a plurality of panels and at least one flap is provided. The shell has a substantially planar unfolded state and a first folded state that defines a container suitable to hold an object to be sterilized. Optionally, the foldable shell may have a liner attached thereto. A method of folding a foldable shell and a liner to prepare an object for sterilization is also provided. The method results in the formation of the container while simultaneously enfolding the liner around an object disposed on the foldable shell.
Abstract translation: 提供具有多个面板和至少一个折片的可折叠壳体。 壳体具有基本平坦的展开状态和限定适合于容纳待消毒物体的容器的第一折叠状态。 可选地，可折叠外壳可以具有连接到其上的衬垫。 还提供了折叠可折叠壳和衬垫以制备灭菌对象的方法。 该方法导致容器的形成，同时将衬垫围绕设置在可折叠壳体上的物体包围。
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公开(公告)号：US09717812B2
公开(公告)日：2017-08-01
申请号：US14625176
申请日：2015-02-18
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Sailaja Chandrapati , Jeffrey C. Pederson , Heather M. Webb , Jeffrey D. Smith , Kurt J. Halverson , Bryan S. Behun , Peter D. Ludowise
Abstract: A biological sterilization indicator, system, and methods of determining the effectiveness of a sterilization process. The biological sterilization indicator can include a locus of spores, a reservoir containing a liquid, and a sterilant path positioned to provide fluid communication between ambience and the locus of spores. The reservoir can have a closed state in which the reservoir is not in fluid communication with the locus of spores and an open state in which the reservoir is in fluid communication with the locus of spores. The biological sterilization indicator system can include the biological sterilization indicator and a detection device adapted to be coupled to the biological sterilization indicator. In some embodiments, the method can include assaying the spores for a detectable change in a characteristic, and detecting substantially all of the detectable change.
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公开(公告)号：US09358071B2
公开(公告)日：2016-06-07
申请号：US14506944
申请日：2014-10-06
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Kevin D. Landgrebe , Susan K. Reed , Heather M. Webb
CPC classification number: A61B50/30 , A61B46/00 , A61B2050/002 , A61L2/26 , A61L2202/181
Abstract: A method of sterilizing an article is provided. The method includes providing sterilization wrap system with which to wrap the article to be sterilized. The sterilization wrap system comprises a plurality of wrap units configured in a stack, at least one wrap unit in the stack being detachably attached to at least one other wrap unit in the stack.
Abstract translation: 提供了一种消毒物品的方法。 该方法包括提供消毒包装系统，用于包裹待消毒的物品。 灭菌包装系统包括多个构造成堆叠的包装单元，堆叠中的至少一个包装单元可拆卸地附接到堆叠中的至少一个其它包装单元。
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公开(公告)号：US09279141B2
公开(公告)日：2016-03-08
申请号：US14453797
申请日：2014-08-07
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Sailaja Chandrapati , Heather M. Webb , Jeffrey C. Pederson , Kurt J. Halverson , Brian J. Engel
Abstract: The present invention provides method of detecting a predetermined biological activity. The method includes using an aqueous mixture comprising a first indicator reagent with a first absorption spectrum and a second indicator reagent. The second indicator reagent is converted by the predetermined biological activity to a second biological derivative with a second emission spectrum. The first absorbance spectrum includes detectable absorbance in at least a portion of wavelengths present in the second emission spectrum. The first indicator reagent is received and concentrated from an aqueous liquid by a substrate, facilitating the detection of the second biological derivative.
Abstract translation: 本发明提供了检测预定生物活性的方法。 该方法包括使用包含具有第一吸收光谱的第一指示剂和第二指示剂试剂的含水混合物。 第二指示剂通过预定的生物活性转化为具有第二发射光谱的第二生物衍生物。 第一吸收光谱包括在第二发射光谱中存在的波长的至少一部分中的可检测吸光度。 第一指示剂被含水液体接收并通过底物浓缩，便于检测第二生物衍生物。
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