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    SYRINGE WITH TWO-STAGE SEALING PRESSURE
    1.
    发明申请
    SYRINGE WITH TWO-STAGE SEALING PRESSURE 审中-公开

    公开(公告)号：US20170189620A1

    公开(公告)日：2017-07-06

    申请号：US15462131

    申请日：2017-03-17

    Applicant: AbbVie Inc.

    Inventor： Sean E. Mackey ,  Ji Zhou ,  Martin J. Gibler ,  Dennis Y. Lee

    IPC: A61M5/315

    CPC classification number: A61M5/31513 ,  A61J7/0053 ,  A61J15/0015 ,  A61J15/0061 ,  A61J15/0069 ,  A61J15/0076 ,  A61M5/002 ,  A61M5/14546 ,  A61M5/3135 ,  A61M5/31501 ,  A61M5/31505 ,  A61M2005/3101 ,  A61M2005/3106 ,  A61M2005/3131 ,  A61M2005/31506 ,  A61M2205/8206

    Abstract: A syringe includes a barrel, a plunger, and a sealing member creating a seal between the plunger and the barrel. The barrel includes a first portion with a first inner diameter and a second portion with a second inner diameter that is larger than the first inner diameter. The sealing member engages the first portion of the barrel to give rise to a first contact pressure when the barrel is filled with product. The first contact pressure is sufficient to maintain a gas-tight seal over the expected temperature ranges −25° C. to 40° C. A first force is applied to the plunger to overcome the first contact pressure and move the plunger out of the first portion and into the second portion to dispense product. The sealing member engages the second portion of the barrel to give rise to a second contact pressure that is lower than the first contact pressure. A second force lower than the first force is sufficient to overcome the second contact pressure and move the plunger in the second portion to continue dispensing product. The syringe may include a restraining element for accommodating expansion of the product during freezing.

    Devices And Methods For Delivering A Beneficial Agent To A User
    4.
    发明申请
    Devices And Methods For Delivering A Beneficial Agent To A User 审中-公开
    向用户提供有益代理的设备和方法

    公开(公告)号：US20160082184A1

    公开(公告)日：2016-03-24

    申请号：US14863312

    申请日：2015-09-23

    Applicant: AbbVie Inc.

    Inventor： Ted Hanagan ,  Wayne Klingler ,  Thomas Grazier ,  Gurjinder Dhami ,  Scott Smieja ,  Jeff Schacherl ,  Sean Mackey ,  Megan Feilen ,  Ji Zhou ,  Rajkumar Conjeevaram ,  Martin Gibler

    IPC: A61M5/168

    CPC classification number: A61M5/16804 ,  A61J1/10 ,  A61M5/14228 ,  A61M5/14232 ,  A61M5/162 ,  A61M2205/123

    Abstract: Drug delivery reservoir for delivery of a beneficial agent to a user includes a drug delivery reservoir housing having a fluid reservoir defined therein. The drug delivery reservoir housing has a drug delivery reservoir base region. The drug delivery reservoir includes a dip tube extending inside the fluid reservoir. The dip tube includes a tubular wall defining a flow lumen. The tubular wall has at least one aperture defined therein and spaced proximally from a distal end of the tubular wall in fluid communication with the fluid reservoir. The drug delivery reservoir includes an adaptor disposed external to the drug delivery reservoir housing and coupled to a proximal end of the dip tube.

    Abstract translation: 用于将有益剂递送给使用者的药物递送储存器包括具有限定在其中的流体储存器的药物递送储存器壳体。 药物输送储存器壳体具有药物输送储存器基部区域。 药物递送储存器包括在流体储存器内延伸的浸渍管。 汲取管包括限定流动腔的管状壁。 管状壁具有限定在其中的至少一个孔，并与管状壁的远端间隔开并与流体储存器流体连通。 药物递送储存器包括设置在药物输送储存器壳体外部并连接到汲取管的近端的适配器。

    SYRINGE WITH TWO-STAGE SEALING PRESSURE
    5.
    发明申请
    SYRINGE WITH TWO-STAGE SEALING PRESSURE 有权

    公开(公告)号：US20210379290A1

    公开(公告)日：2021-12-09

    申请号：US17151077

    申请日：2021-01-15

    Applicant: AbbVie Inc.

    Inventor： Sean E. Mackey ,  Ji Zhou ,  Martin J. Gibler ,  Dennis Y. Lee

    IPC: A61M5/315 ,  A61M5/145

    Abstract: A syringe includes a barrel, a plunger, and a sealing member creating a seal between the plunger and the barrel. The barrel includes a first portion with a first inner diameter and a second portion with a second inner diameter that is larger than the first inner diameter. The sealing member engages the first portion of the barrel to give rise to a first contact pressure when the barrel is filled with product. The first contact pressure is sufficient to maintain a gas-tight seal over the expected temperature ranges −25° C. to 40° C. A first force is applied to the plunger to overcome the first contact pressure and move the plunger out of the first portion and into the second portion to dispense product. The sealing member engages the second portion of the barrel to give rise to a second contact pressure that is lower than the first contact pressure. A second force lower than the first force is sufficient to overcome the second contact pressure and move the plunger in the second portion to continue dispensing product. The syringe may include a restraining element for accommodating expansion of the product during freezing.

    PUMP, MOTOR AND ASSEMBLY FOR BENEFICIAL AGENT DELIVERY
    6.
    发明申请
    PUMP, MOTOR AND ASSEMBLY FOR BENEFICIAL AGENT DELIVERY 审中-公开

    公开(公告)号：US20190143034A1

    公开(公告)日：2019-05-16

    申请号：US16243662

    申请日：2019-01-09

    Applicant: ABBVIE INC.

    Inventor： Phil D. Anderson ,  Rajkumar Conjeevaram ,  Ji Zhou ,  Sean Mackey ,  Kevin Novak ,  Ted Hanagan ,  Mark Panzer ,  Benjamin Greuel ,  Jim Hoch ,  Ryan Thompson

    IPC: A61M5/168 ,  F04B43/12 ,  F04B43/08 ,  A61M5/142

    Abstract: Device for delivering a beneficial agent to a user includes a cassette including a cassette housing with a fluid reservoir, the cassette housing having a cassette base region, and a delivery tube. The device also includes a pump having a pump housing containing a pump assembly and having a receiving region to receive the cassette base region. The pump assembly includes a fluid drive component, a display, a plurality of input buttons. The pump assembly also includes a first processor coupled to the fluid drive component and the display and configured to reduce power to the fluid drive component and the display when the pump is in an inactive state, and a second processor coupled to the first processor and the plurality of input buttons, the second processor configured to provide an activation signal to the first processor when one or more of the plurality of input buttons is deployed.

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