公开(公告)号：US09925235B2

公开(公告)日：2018-03-27

申请号：US15137281

申请日：2016-04-25

Applicant: Academia Sinica ,  National Taiwan Ocean University

Inventor： Jyh-Yih Chen ,  Chang-Jer Wu

IPC: A61K38/16 ,  A61K38/17 ,  C07K14/00 ,  C07K4/12

CPC classification number: A61K38/1706

Abstract: A method for enhancing wound healing or treating methicillin-resistant Staphylococcus aureus (MRSA) infection in a wound comprising administering a subject in need thereof with a therapeutically effective amount of a tilapia piscidin (TP) is described, wherein the TP is preferably TP3 or TP4.

公开(公告)号：US09750844B2

公开(公告)日：2017-09-05

申请号：US14857189

申请日：2015-09-17

Applicant: ACADEMIA SINICA ,  NATIONAL TAIWAN OCEAN UNIVERSITY

Inventor： Jyh-Yih Chen ,  Chang-Jer Wu ,  Han-Ning Huang

IPC: A61L26/00 ,  A61L15/46 ,  A61L15/32

CPC classification number: A61L26/0047 ,  A61L15/32 ,  A61L15/325 ,  A61L15/46 ,  A61L26/0033 ,  A61L26/0066 ,  A61L2300/252 ,  A61L2300/404 ,  A61L2300/412

Abstract: The preset invention relates to a new method for wound healing, particularly in burns, comprising Epinecidin-1 (Epi-1) or Pardaxin (GE33), optionally in the incorporation into collagen.

公开(公告)号：US09901615B2

公开(公告)日：2018-02-27

申请号：US15098486

申请日：2016-04-14

Applicant: Academia Sinica ,  National Taiwan Ocean University

Inventor： Jyh-Yih Chen ,  Chang-Jer Wu

IPC: A61K38/17 ,  C07K14/435 ,  A61P31/04

CPC classification number: A61K38/1706

Abstract: The preset invention relates to a new method or composition for treating a gastric ulcer, preventing or treating an infection of H. pylori, particularly multidrug resistant H. pylori, using an antimicrobial peptide, a functional derivate, fragment or variant thereof, wherein the antimicrobial peptide is selected from the group consisting of Epi-1, TPs and combination thereof.