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    ASEPTIC CONNECTOR
    1.
    发明申请
    ASEPTIC CONNECTOR 审中-公开

    公开(公告)号：US20190021951A1

    公开(公告)日：2019-01-24

    申请号：US16143048

    申请日：2018-09-26

    申请人： ADVANCED SCIENTIFICS, INC.

    发明人： Rudolf Pavlik

    IPC分类号： A61J1/20 ,  A61M39/16 ,  A61M39/10 ,  A61M39/18 ,  A61M39/12 ,  A61M39/24 ,  B65B3/00

    摘要： An aseptic connector assembly includes a body portion having a receptacle configured to receive a corresponding fill connector. A pivot portion is movably coupled to the body portion, the pivot portion having a channel formed therein. A conduit portion is slidably disposed within the channel formed in the pivot portion. The pivot portion has a ready position and an operative position, the pivot portion being adjustable from the ready position to the operative position via relative movement with respect to the body portion.

    TRANSPORTABLE MIXING SYSTEM FOR BIOLOGICAL AND PHARMACEUTICAL MATERIALS
    2.
    发明申请
    TRANSPORTABLE MIXING SYSTEM FOR BIOLOGICAL AND PHARMACEUTICAL MATERIALS 审中-公开

    公开(公告)号：US20190336926A1

    公开(公告)日：2019-11-07

    申请号：US16515322

    申请日：2019-07-18

    申请人： ADVANCED SCIENTIFICS, INC.

    发明人： Rudolf Pavlik

    IPC分类号： B01F13/00 ,  B01F15/00 ,  B65D77/06 ,  B01F7/16

    摘要： A mixing system includes a container having a support plate and a mixing assembly supported on the support plate. The mixing assembly includes a pliable enclosure containing a fluid and a mixing device. A portion of the mixing device extends from the pliable enclosure and is adapted to be detachably coupled to a drive mechanism. A first plate is detachably secured to the rigid container. The pliable enclosure is disposed between the first plate and the support plate. A mixing arrangement includes a docking station having a drive cradle and a drive mechanism. The mixing system is removably positioned within the drive cradle so that the drive mechanism is removably coupled to the mixing device.

    TEST SYSTEM AND METHOD FOR FLEXIBLE CONTAINERS
    5.
    发明申请
    TEST SYSTEM AND METHOD FOR FLEXIBLE CONTAINERS 有权
    柔性容器的测试系统和方法

    公开(公告)号：US20160161361A1

    公开(公告)日：2016-06-09

    申请号：US15044830

    申请日：2016-02-16

    申请人： ADVANCED SCIENTIFICS, INC.

    发明人： Rudolf Pavlik

    IPC分类号： G01M3/32

    CPC分类号： G01M3/3218 ,  G01M3/3263

    摘要： A portable test device and related method are disclosed for conducting integrity testing of flexible containers. The test is particularly useful for testing aseptic flexible film bags in a manner that maintains the sterile nature of the container and removes crinkles by inflating the containers to remove crinkles and establish an inflation set point. The decay in pressure is measured over a predetermined period of time; if pressure loss does not exceed a predetermined threshold the integrity of the bag is confirmed and it can be filled without further manipulation of the container that may result in introducing flaws.

    摘要翻译： 公开了用于进行柔性容器的完整性测试的便携式测试装置和相关方法。 该测试对于以保持容器的无菌性质的方式测试无菌柔性膜袋特别有用，并通过使容器膨胀以除去皱纹并建立充气设定点来消除皱纹。 在预定的时间段内测量压力衰减; 如果压力损失不超过预定阈值，则确认袋的完整性，并且可以在不进一步操纵可能导致缺陷的容器的情况下填充袋。

    Transportable mixing system for biological and pharmaceutical materials
    6.
    发明授权
    Transportable mixing system for biological and pharmaceutical materials 有权

    公开(公告)号：US11179687B2

    公开(公告)日：2021-11-23

    申请号：US16515322

    申请日：2019-07-18

    申请人： ADVANCED SCIENTIFICS, INC.

    发明人： Rudolf Pavlik

    IPC分类号： B01F13/00 ,  B01F15/00 ,  B01F7/16 ,  B65D77/06 ,  B01F1/00

    摘要： A mixing system includes a container having a support plate and a mixing assembly supported on the support plate. The mixing assembly includes a pliable enclosure containing a fluid and a mixing device. A portion of the mixing device extends from the pliable enclosure and is adapted to be detachably coupled to a drive mechanism. A first plate is detachably secured to the rigid container. The pliable enclosure is disposed between the first plate and the support plate. A mixing arrangement includes a docking station having a drive cradle and a drive mechanism. The mixing system is removably positioned within the drive cradle so that the drive mechanism is removably coupled to the mixing device.

    Pressure decay testing system and testing device for a connector and method of testing
    9.
    发明授权
    Pressure decay testing system and testing device for a connector and method of testing 有权
    用于连接器的压力衰减测试系统和测试装置以及测试方法

    公开(公告)号：US09476794B2

    公开(公告)日：2016-10-25

    申请号：US13934684

    申请日：2013-07-03

    申请人： ADVANCED SCIENTIFICS, INC.

    发明人： Rudolf Pavlik

    IPC分类号： G01M3/08 ,  G01M3/26

    CPC分类号： G01M3/26

    摘要： A pressure decay testing system including a testing device for determining the reliability of connectors is provided and includes a pneumatic cylinder that raises and lowers a sealing member that closes a second end of a connector inserted in the device. A base member is adjacent pneumatic cylinder and includes a receiving surface having at least one receiving member for holding the connector. A channel is disposed therethrough though the receiving surface of the base member and aligns with an inner bore of the connector inserted in the testing device. An air line is attached to base member fluidly connecting inner bore of the connector with decay tester. Decay tester introduces a pressure differential through the channel to reach a predetermined set point pressure when the connector is closed by the testing device. Decay tester is configured to measure a change in pressure over time with respect to the predetermined set point.

    摘要翻译： 提供了包括用于确定连接器的可靠性的测试装置的压力衰减测试系统，并且包括气动缸，其升高并降低了封闭插入到装置中的连接器的第二端的密封构件。 基座构件邻近气缸，并且包括具有用于保持连接器的至少一个接收构件的接收表面。 通道穿过基底构件的接收表面设置并与插入测试装置中的连接器的内孔对准。 将空气管线连接到基座部件上，使连接器的内孔与衰减测试器流体连接。 当连接器被测试装置关闭时，衰减测试仪通过通道引入压差以达到预定的设定点压力。 衰减测试器被配置成测量相对于预定设定点的时间上的压力变化。

    Mixing assembly and mixing method
    10.
    发明授权
    Mixing assembly and mixing method 有权
    混合组装和混合方法

    公开(公告)号：US09101893B1

    公开(公告)日：2015-08-11

    申请号：US14338573

    申请日：2014-07-23

    申请人： ADVANCED SCIENTIFICS, INC.

    发明人： Rudolf Pavlik

    IPC分类号： B01F11/00 ,  B01F15/00

    CPC分类号： B01F15/0085 ,  B01F3/1221 ,  B01F11/0048 ,  B01F11/0082 ,  B01F15/00129 ,  B01F15/00155 ,  B01F15/00207 ,  B01F15/00253 ,  B01F15/00259 ,  B01F15/00402 ,  B01F15/00467 ,  B01F15/00538 ,  B01F2215/0073 ,  C12M23/14

    摘要： A mixing system and mixing method are provided. The mixing system includes a tank assembly, a container positioned within the tank assembly, a mixer disposed within a compartment of the container, a linear motor, and a shaft having a first end secured to the mixer and an opposing second end secured to the linear motor. The linear motor provides a variable stroke length for the shaft. The mixing method includes providing a tank assembly having a linear motor, positioning a mixing assembly including a mixing bag in the tank assembly, combining two or more components in a compartment of the mixing bag, attaching a mixing shaft extending from a mixer disposed within the mixing bag to the linear motor, and raising and lowering the mixing shaft to mix the two or more components. A stroke length of the mixing shaft during the raising and lowering is varied.

    摘要翻译： 提供了一种混合系统和混合方法。 混合系统包括罐组件，位于罐组件内的容器，设置在容器的隔室内的混合器，线性马达和具有固定到混合器的第一端的轴，以及固定到线性的相对的第二端 发动机。 线性电机为轴提供了可变行程长度。 该混合方法包括提供具有线性马达的罐组件，将包括混合袋的混合组件定位在罐组件中，将混合袋的隔室中的两个或更多个部件组合在一起，将从设置在该混合袋内的混合器延伸的混合轴 混合袋到线性马达，以及升降混合轴以混合两个或更多个部件。 混合轴在升降过程中的行程长度变化。