公开(公告)号：US20190233823A1

公开(公告)日：2019-08-01

申请号：US16312207

申请日：2017-08-30

Applicant: AEROVIRUS TECHNOLOGIES INC.

Inventor： Norman J MARCHAND ,  Thomas G CALTAGIRONE ,  Albert Liao

IPC: C12N15/115 ,  A61K31/713 ,  C12Q1/689 ,  C07K16/12 ,  C12N15/10 ,  A61P31/04

CPC classification number: C12N15/115 ,  A61K31/713 ,  A61P31/04 ,  C07H21/00 ,  C07K16/1253 ,  C12N15/1048 ,  C12N2310/16 ,  C12Q1/04 ,  C12Q1/689 ,  G01N2333/30

Abstract: The present invention relates to aptamers, polynucleotides, and nucleic acid molecules, which include a polynucleotide sequence capable of specifically binding polypeptides participating in M. Hyopneumoniae infection. Also provided are methods of using nucleic acid molecules, polynucleotides and synthetic antibodies directed there against for detection, treating and neutralization of M. Hyopneumoniae infection.

公开(公告)号：US11001846B2

公开(公告)日：2021-05-11

申请号：US16060001

申请日：2016-12-01

Applicant: AEROVIRUS TECHNOLOGIES INC.

Inventor： Norman Marchand ,  Thomas Caltagirone ,  Albert Liao

IPC: C12N15/11 ,  C12N15/115 ,  A61K31/711 ,  C12Q1/70 ,  C07K16/10 ,  G01N33/53 ,  C12Q1/68 ,  A61K31/7088 ,  A61P31/14

Abstract: Aptamers, polynucleotides which participate in preventing the Porcine Respiratory and Reproductive Syndrome virus (PRRSV) infection of cells, and nucleic acid molecules, which include a polynucleotide sequence capable of specifically binding the polypeptides domain of the PRRSV that controls infection, constitute the core of the present invention. Also provided are methods of using such nucleic acid molecules, polynucleotides and synthetic antibodies directed against these, for detection, treating and neutralization of PRRSV infection.

公开(公告)号：US11753645B2

公开(公告)日：2023-09-12

申请号：US17685727

申请日：2022-03-03

Applicant: AEROVIRUS TECHNOLOGIES INC.

Inventor： Norman J Marchand ,  Thomas G Caltagirone ,  Albert Liao

IPC: C12N15/115 ,  C07H21/00 ,  C12Q1/04 ,  A61P31/04 ,  A61K31/713 ,  C07K16/12 ,  C12N15/10 ,  C12Q1/689

CPC classification number: C12N15/115 ,  A61K31/713 ,  A61P31/04 ,  C07H21/00 ,  C07K16/1253 ,  C12N15/1048 ,  C12Q1/04 ,  C12Q1/689 ,  C12N2310/16 ,  G01N2333/30

Abstract: The present disclosure relates to aptamers, polynucleotides, and nuclei acid molecules, which include a polynucleotide sequence capable of specifically binding polypeptides participating in M. hyopneumoniae infection. Also provided are methods of using nucleic acid molecules, polynucleotides and synthetic antibodies directed there against for detection, treating and neutralization of M. hyopneumoniae infection.

公开(公告)号：US20220186225A1

公开(公告)日：2022-06-16

申请号：US17685727

申请日：2022-03-03

Applicant: AEROVIRUS TECHNOLOGIES INC.

Inventor： Norman J MARCHAND ,  Thomas G CALTAGIRONE ,  Albert Liao

IPC: C12N15/115 ,  C07H21/00 ,  C12Q1/04 ,  A61P31/04 ,  A61K31/713 ,  C07K16/12 ,  C12N15/10 ,  C12Q1/689

Abstract: The present disclosure relates to aptamers, polynucleotides, and nuclei acid molecules, which include a polynucleotide sequence capable of specifically binding polypeptides participating in M. Hyopneumoniae infection. Also provided are methods of using nucleic acid molecules, polynucleotides and synthetic antibodies directed there against for detection, treating and neutralization of M. Hyopneumoniae infection.