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公开(公告)号:US20190233823A1
公开(公告)日:2019-08-01
申请号:US16312207
申请日:2017-08-30
Applicant: AEROVIRUS TECHNOLOGIES INC.
Inventor: Norman J MARCHAND , Thomas G CALTAGIRONE , Albert Liao
IPC: C12N15/115 , A61K31/713 , C12Q1/689 , C07K16/12 , C12N15/10 , A61P31/04
CPC classification number: C12N15/115 , A61K31/713 , A61P31/04 , C07H21/00 , C07K16/1253 , C12N15/1048 , C12N2310/16 , C12Q1/04 , C12Q1/689 , G01N2333/30
Abstract: The present invention relates to aptamers, polynucleotides, and nucleic acid molecules, which include a polynucleotide sequence capable of specifically binding polypeptides participating in M. Hyopneumoniae infection. Also provided are methods of using nucleic acid molecules, polynucleotides and synthetic antibodies directed there against for detection, treating and neutralization of M. Hyopneumoniae infection.
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公开(公告)号:US20220163437A1
公开(公告)日:2022-05-26
申请号:US17580557
申请日:2022-01-20
Applicant: AEROVIRUS TECHNOLOGIES INC.
Inventor: Norman MARCHAND , Carmine GRAZIANO
Abstract: Disclosed herein are devices and methods for the real-time detection of aeropathogens. The device includes an aerosampler having an air inlet and at least one collector tube, a microfluidic system which includes a container, piping, a micro-pump for flowing a liquid, and a viral detection chamber. The viral detection chamber has an electrode which may be equipped with functionalized biosensors, a counter electrode, an electronic detection system connectable to the electrodes of the viral detection chamber, and an embedded electronic processing system for processing data from the electronic detection system.
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公开(公告)号:US11635362B2
公开(公告)日:2023-04-25
申请号:US16342191
申请日:2016-11-15
Applicant: AEROVIRUS TECHNOLOGIES INC.
Inventor: Norman Marchand , Carmine Graziano
IPC: G01N15/06 , G01N15/02 , B01D11/04 , G01N27/00 , B01L9/00 , B01L3/00 , B01L5/00 , G01N33/569 , C12Q1/70 , G01N15/00 , G01N27/447 , G01N15/04 , C12Q1/6804
Abstract: The invention provides a device and method for the real-time detection of aeropathogens. The device includes an aerosampler having an air inlet and at least one collector tube, a microfluidic system which includes a container, piping, a micro pump for flowing a liquid and a viral detection chamber. The viral detection chamber has an electrode which may be equipped with functionalized bio sensors, a counter electrode, an electronic detection system connectable to the electrodes of the viral detection chamber, and an embedded electronic processing system for processing data from the electronic detection system.
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公开(公告)号:US11001846B2
公开(公告)日:2021-05-11
申请号:US16060001
申请日:2016-12-01
Applicant: AEROVIRUS TECHNOLOGIES INC.
Inventor: Norman Marchand , Thomas Caltagirone , Albert Liao
IPC: C12N15/11 , C12N15/115 , A61K31/711 , C12Q1/70 , C07K16/10 , G01N33/53 , C12Q1/68 , A61K31/7088 , A61P31/14
Abstract: Aptamers, polynucleotides which participate in preventing the Porcine Respiratory and Reproductive Syndrome virus (PRRSV) infection of cells, and nucleic acid molecules, which include a polynucleotide sequence capable of specifically binding the polypeptides domain of the PRRSV that controls infection, constitute the core of the present invention. Also provided are methods of using such nucleic acid molecules, polynucleotides and synthetic antibodies directed against these, for detection, treating and neutralization of PRRSV infection.
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公开(公告)号:US20190242807A1
公开(公告)日:2019-08-08
申请号:US16342191
申请日:2016-11-15
Applicant: AEROVIRUS TECHNOLOGIES INC.
Inventor: Norman MARCHAND , Carmine GRAZIANO
CPC classification number: G01N15/0656 , B01L3/502715 , B01L3/50273 , B01L5/00 , B01L2300/0636 , C12Q1/6804 , C12Q1/70 , G01N15/0255 , G01N15/0266 , G01N15/042 , G01N15/0606 , G01N33/56983 , G01N2015/0065 , G01N2015/0288 , C12Q2525/205 , C12Q2563/116 , C12Q2565/629
Abstract: The invention provides a device and method for the real-time detection of aeropathogens. The device includes an aerosampler having an air inlet and at least one collector tube, a microfluidic system which includes a container, piping, a micro pump for flowing a liquid and a viral detection chamber. The viral detection chamber has an electrode which may be equipped with functionalized bio sensors, a counter electrode, an electronic detection system connectable to the electrodes of the viral detection chamber, and an embedded electronic processing system for processing data from the electronic detection system.
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公开(公告)号:US11753645B2
公开(公告)日:2023-09-12
申请号:US17685727
申请日:2022-03-03
Applicant: AEROVIRUS TECHNOLOGIES INC.
Inventor: Norman J Marchand , Thomas G Caltagirone , Albert Liao
IPC: C12N15/115 , C07H21/00 , C12Q1/04 , A61P31/04 , A61K31/713 , C07K16/12 , C12N15/10 , C12Q1/689
CPC classification number: C12N15/115 , A61K31/713 , A61P31/04 , C07H21/00 , C07K16/1253 , C12N15/1048 , C12Q1/04 , C12Q1/689 , C12N2310/16 , G01N2333/30
Abstract: The present disclosure relates to aptamers, polynucleotides, and nuclei acid molecules, which include a polynucleotide sequence capable of specifically binding polypeptides participating in M. hyopneumoniae infection. Also provided are methods of using nucleic acid molecules, polynucleotides and synthetic antibodies directed there against for detection, treating and neutralization of M. hyopneumoniae infection.
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公开(公告)号:US11740172B2
公开(公告)日:2023-08-29
申请号:US17580557
申请日:2022-01-20
Applicant: AEROVIRUS TECHNOLOGIES INC.
Inventor: Norman Marchand , Carmine Graziano
IPC: G01N15/06 , G01N15/02 , B01D11/04 , G01N27/00 , B01L9/00 , B01L3/00 , B01L5/00 , G01N33/569 , C12Q1/70 , G01N15/00 , G01N27/447 , G01N15/04 , C12Q1/6804
CPC classification number: G01N15/0656 , B01D11/0496 , B01L3/50273 , B01L3/502715 , B01L5/00 , B01L9/527 , G01N15/0255 , G01N15/0266 , G01N15/042 , G01N15/0606 , G01N27/00 , G01N33/56983 , B01L2300/0636 , C12Q1/6804 , C12Q1/70 , G01N27/44791 , G01N2015/0065 , G01N2015/0288 , C12Q1/6804 , C12Q2525/205 , C12Q2563/116 , C12Q2565/629 , C12Q1/70 , C12Q2525/205 , C12Q2563/116 , C12Q2565/629
Abstract: Disclosed herein are devices and methods for the real-time detection of aeropathogens. The device includes an aerosampler having an air inlet and at least one collector tube, a microfluidic system which includes a container, piping, a micro-pump for flowing a liquid, and a viral detection chamber. The viral detection chamber has an electrode which may be equipped with functionalized biosensors, a counter electrode, an electronic detection system connectable to the electrodes of the viral detection chamber, and an embedded electronic processing system for processing data from the electronic detection system.
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公开(公告)号:US20220186225A1
公开(公告)日:2022-06-16
申请号:US17685727
申请日:2022-03-03
Applicant: AEROVIRUS TECHNOLOGIES INC.
Inventor: Norman J MARCHAND , Thomas G CALTAGIRONE , Albert Liao
IPC: C12N15/115 , C07H21/00 , C12Q1/04 , A61P31/04 , A61K31/713 , C07K16/12 , C12N15/10 , C12Q1/689
Abstract: The present disclosure relates to aptamers, polynucleotides, and nuclei acid molecules, which include a polynucleotide sequence capable of specifically binding polypeptides participating in M. Hyopneumoniae infection. Also provided are methods of using nucleic acid molecules, polynucleotides and synthetic antibodies directed there against for detection, treating and neutralization of M. Hyopneumoniae infection.
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公开(公告)号:US20180371461A1
公开(公告)日:2018-12-27
申请号:US16060001
申请日:2016-12-01
Applicant: AEROVIRUS TECHNOLOGIES INC.
Inventor: Norman MARCHAND , Thomas CALTAGIRONE , Albert LIAO
IPC: C12N15/115 , C07K16/10 , A61K31/711 , C12Q1/70 , G01N33/53 , A61P31/14
Abstract: Aptamers, polynucleotides which participate in preventing the Porcine Respiratory and Reproductive Syndrome virus (PRRSV) infection of cells, and nucleic acid molecules, which include a polynucleotide sequence capable of specifically binding the polypeptides domain of the PRRSV that controls infection, constitute the core of the present invention. Also provided are methods of using such nucleic acid molecules, polynucleotides and synthetic antibodies directed against these, for detection, treating and neutralization of PRRSV infection.
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