公开(公告)号：US11753645B2

公开(公告)日：2023-09-12

申请号：US17685727

申请日：2022-03-03

Applicant: AEROVIRUS TECHNOLOGIES INC.

Inventor： Norman J Marchand ,  Thomas G Caltagirone ,  Albert Liao

IPC: C12N15/115 ,  C07H21/00 ,  C12Q1/04 ,  A61P31/04 ,  A61K31/713 ,  C07K16/12 ,  C12N15/10 ,  C12Q1/689

CPC classification number: C12N15/115 ,  A61K31/713 ,  A61P31/04 ,  C07H21/00 ,  C07K16/1253 ,  C12N15/1048 ,  C12Q1/04 ,  C12Q1/689 ,  C12N2310/16 ,  G01N2333/30

Abstract: The present disclosure relates to aptamers, polynucleotides, and nuclei acid molecules, which include a polynucleotide sequence capable of specifically binding polypeptides participating in M. hyopneumoniae infection. Also provided are methods of using nucleic acid molecules, polynucleotides and synthetic antibodies directed there against for detection, treating and neutralization of M. hyopneumoniae infection.