-
公开(公告)号：US20180194853A1
公开(公告)日：2018-07-12
申请号：US15908218
申请日：2018-02-28
IPC分类号： C07K16/28 , C07K16/24 , A61K38/20 , C12N5/0783 , A61P35/00
CPC分类号： C07K16/2896 , A61K38/2013 , A61K2039/505 , A61P35/00 , C07K16/246 , C07K16/2866 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/524 , C07K2317/526 , C07K2317/567 , C07K2317/622 , C07K2317/71 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , C12N5/0636 , C12N5/0646
摘要： Anti-CD122 and/or γc antibodies and fragments thereof are disclosed. Also disclosed are compositions comprising such antibodies and fragments, and uses and methods using the same.
-
公开(公告)号：US20210155685A1
公开(公告)日：2021-05-27
申请号：US17150689
申请日：2021-01-15
发明人： Cheng-I WANG , Angeline GOH , Siok Ping YEO , Alessandra Rosa MORTELLARO , Subhra Kumar BISWAS , Florent GINHOUX , Pingyu ZHONG
IPC分类号： C07K16/24 , A61K39/395
摘要： The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
-
公开(公告)号：US20160367664A1
公开(公告)日：2016-12-22
申请号：US15229336
申请日：2016-08-05
IPC分类号： A61K39/395 , C07K16/28
CPC分类号： C07K16/2866 , A61K38/1709 , A61K39/3955 , A61K47/6849 , A61K2039/505 , A61K2039/57 , C07K16/1036 , C07K16/468 , C07K2317/31 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/526 , C07K2317/565 , C07K2317/60 , C07K2317/622 , C07K2317/64 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C07K2319/00
摘要： Anti-CD122 and/or γc antibodies and fragments thereof are disclosed. Also disclosed are compositions comprising such antibodies and fragments, and uses and methods using the same.
摘要翻译： 公开了抗CD122和/或γc抗体及其片段。 还公开了包含这种抗体和片段的组合物，以及使用它们的用途和方法。
-
公开(公告)号：US20210024627A1
公开(公告)日：2021-01-28
申请号：US17061194
申请日：2020-10-01
发明人： Cheng-I WANG , Angeline GOH , Siok Ping YEO , Alessandra Rosa MORTELLARO , Subhra Kumar BISWAS , Florent GINHOUX , Pingyu ZHONG
IPC分类号： C07K16/24 , A61K39/395
摘要： The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
-
公开(公告)号：US20200055935A1
公开(公告)日：2020-02-20
申请号：US16551944
申请日：2019-08-27
IPC分类号： C07K16/28 , A61K39/395
摘要： Anti-TIM-3 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
-
公开(公告)号：US20230080224A1
公开(公告)日：2023-03-16
申请号：US17798025
申请日：2021-02-05
发明人： William SUN , Boon Ooi Patrick TAN , Huajing WANG , Thai Leong YAP , Shin Yee HONG , Cheng-I WANG , Ching-Wen HUANG , Shuet Theng LEE , Kah Fei WAN , Jian Duan Johnathan NG
IPC分类号： C07K16/40 , G01N33/573 , G01N33/574 , A61P35/00
摘要： The invention relates to antigen-binding molecules that specifically binds ALPPL2 and/or ALPP but not ALPL or ALPI. It also relates to a pharmaceutical composition, an immunoconjugate and a chimeric antigen receptor comprising said antigen-binding molecules. The invention also relates to methods for reducing the expression or activity of ALPPL2 in a cancer cell and methods of treating a cancer in a subject.
-
公开(公告)号：US20210155686A1
公开(公告)日：2021-05-27
申请号：US17150691
申请日：2021-01-15
发明人： Cheng-I WANG , Angeline GOH , Siok Ping YEO , Alessandra Rosa MORTELLARO , Subhra Kumar BISWAS , Florent GINHOUX , Pingyu ZHONG
IPC分类号： C07K16/24 , A61K39/395
摘要： The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
-
公开(公告)号：US20180237528A1
公开(公告)日：2018-08-23
申请号：US15750425
申请日：2016-08-05
摘要： Anti-CD122 and/or γc antibodies and fragments thereof are disclosed. Also disclosed are compositions comprising such antibodies and fragments, and uses and methods using the same.
-
公开(公告)号：US20220162335A1
公开(公告)日：2022-05-26
申请号：US17441519
申请日：2020-03-22
发明人： Cheng-I WANG , Bei WANG , Zi Xian Eve NGOH , Wen-Hsin LEE , Ching-Wen HUANG , Yee Chin, Yvonne YEAP
IPC分类号： C07K16/30 , C07K16/28 , C07K14/725 , A61K39/395 , A61K38/17 , A61K47/68 , A61P35/00
摘要： We describe an antibody or antigen-binding fragment thereof comprising a heavy chain variable region (VH) sequence and a light chain variable region (VL) sequence of a clone selected from: 5C4, 4H1, 1D2, 1C4, 2B5, 1F1, 1H1, 4A5, 1D8, 1D3, 2F1, 3C6, 3D12, 3A9, 1F4, 1H10, 3C12, 4G11, 4A12, 1A12, 3G12, 4F9, 4G4 and 1E1 which is capable of specifically binding to glypican-3 (GPC-3) (GenBank Accession Number: NP_004475.1), or a sequence having at least 75%, 80%, 85%, 90%, 95%, 96%, 97%, 98% or 99% sequence identity thereto.
-
公开(公告)号：US20190153097A1
公开(公告)日：2019-05-23
申请号：US16099652
申请日：2017-04-13
发明人： Cheng-I WANG , Eve NGOH , Siok Ping YEO
摘要： Anti-CTLA-4 antibodies are disclosed. Also disclosed are compositions comprising such antibodies, and uses and methods using the same.
-
-
-
-
-
-
-
-
-
搜索结果
13 条记录 (耗时 0.02 秒)
